NUR 529 Exam 2 Set Test Questions and
Revised Correct Answers | Already
Passed|| GRADED A+
Systemic arterial pressure -CORRECTANSWER is the main source of afterload on the
left heart, Left ventricle afterload is increased with narrowing (stenosis) of the aortic
valve
Stages of Hemostasis -CORRECTANSWER Vessel Spasm, formation of the platelet
plug, blood coagulation (clot retraction, clot dissolution)
Vessel Spasm -CORRECTANSWER First stage of hemostasis, constricts the vessel
and reduces blood flow. It is a transient event that usually lasts minutes or hours.
Formation of the platelet plug -CORRECTANSWER Second stage of hemostasis, 1.
platelets are attracted to damaged vessel wall. 2. activation by sub-endothelial tissue. 3.
change from smooth disks to spiny spheres. 4. exposing glycoprotein receptors on their
surfaces. This step requires a protein molecule called von Willebrand factor that leaks
into the injured tissue from the plasma. (adhesion, activation, aggregation)
During Hemostasis, platelets change from ..... -CORRECTANSWER Smooth disks to
spiny spheres
,von Willebrand factor -CORRECTANSWER Formation of the platelet plug requires a
protein molecule called (helps platelets stick together)
Glycoprotein Receptors -CORRECTANSWER Exposed during the formation of the
platelet plug when platelets change from smooth disks to spiny spheres
1.Blood coagulation or development of an insoluble fibrin clot -CORRECTANSWER
Third step of hemostasis: stabilization of the plug occurs as the coagulation pathway is
activated on the platelet surface, and fibrinogen is converted to fibrin.
Thrombocytopenia -CORRECTANSWER Results from a decrease in platelet
production, increased sequestration of platelets in the spleen, or decreased platelet
survival
Drug induced thrombocytopenia -CORRECTANSWER can be from aspirin, atorvastatin,
antibiotics and of course Heparin.
Clot retraction -CORRECTANSWER the consolidation or tightening of the fibrin clot
pulls the edges of the damaged vessel close together, allowing for repair of the vessel
lining.
,Clot dissolution -CORRECTANSWER fibrinolysis occurs through conversion of
plasminogen to plasmin by tissue plasminogen activator (tPA), which is released from
damaged endothelial cells. This conversion results in digestion of fibrin fibers within the
clot and the production of fibrin degradation products.... Clot dissolves.
Immune thrombocytopenia -CORRECTANSWER was formally called idiopathic
thrombocytopenia purpura. ITP is the most common thrombocytopenic disorder among
children and often follows an upper respiratory infection.
Thrombotic Thrombocytopenic -CORRECTANSWER rare and caused by a deficiency
of the gene responsible for severing large von Willebrand factor proteins. The
unchecked platelet aggregation results in microvascular occlusions...end organ failure
Spontaneous bleeding from platelet disorders -CORRECTANSWER Most often involves
small vessels of mucous membranes and skin, common sites are nose, mouth, GI,
uterine
Cutaneous bleeding -CORRECTANSWER seen as pinpoint hemorrhages (petechiae),
or purple areas of bruising (purpura)
Petechiae -CORRECTANSWER Occur almost exclusively in conditions of platelet
deficiency, not dysfunction
, 120 days -CORRECTANSWER RBC lifespan
Spleen -CORRECTANSWER Breaks down RBC
5 years -CORRECTANSWER Almost all bones produce RBCS to maintain growth rate
until this age
Red bone marrow -CORRECTANSWER RBCS produced here after birth
20 years -CORRECTANSWER Age when red cell production takes place mainly in the
membranous bones of the vertebrae, sternum, ribs, and pelvis and red marrow changes
to fatty yellow due to decreased activity
Iron and amino acids -CORRECTANSWER Degradation products recycled when RBCS
are broken down
Hematocrit -CORRECTANSWER Measures the volume of red cell mass in 100 mL of
plasma volume
Transfusion reaction symptoms -CORRECTANSWER •Sensation of heat along the vein
where the blood is being infused
•Flushing of the face
•Urticaria/rash, headache, pain in the lumbar area
Revised Correct Answers | Already
Passed|| GRADED A+
Systemic arterial pressure -CORRECTANSWER is the main source of afterload on the
left heart, Left ventricle afterload is increased with narrowing (stenosis) of the aortic
valve
Stages of Hemostasis -CORRECTANSWER Vessel Spasm, formation of the platelet
plug, blood coagulation (clot retraction, clot dissolution)
Vessel Spasm -CORRECTANSWER First stage of hemostasis, constricts the vessel
and reduces blood flow. It is a transient event that usually lasts minutes or hours.
Formation of the platelet plug -CORRECTANSWER Second stage of hemostasis, 1.
platelets are attracted to damaged vessel wall. 2. activation by sub-endothelial tissue. 3.
change from smooth disks to spiny spheres. 4. exposing glycoprotein receptors on their
surfaces. This step requires a protein molecule called von Willebrand factor that leaks
into the injured tissue from the plasma. (adhesion, activation, aggregation)
During Hemostasis, platelets change from ..... -CORRECTANSWER Smooth disks to
spiny spheres
,von Willebrand factor -CORRECTANSWER Formation of the platelet plug requires a
protein molecule called (helps platelets stick together)
Glycoprotein Receptors -CORRECTANSWER Exposed during the formation of the
platelet plug when platelets change from smooth disks to spiny spheres
1.Blood coagulation or development of an insoluble fibrin clot -CORRECTANSWER
Third step of hemostasis: stabilization of the plug occurs as the coagulation pathway is
activated on the platelet surface, and fibrinogen is converted to fibrin.
Thrombocytopenia -CORRECTANSWER Results from a decrease in platelet
production, increased sequestration of platelets in the spleen, or decreased platelet
survival
Drug induced thrombocytopenia -CORRECTANSWER can be from aspirin, atorvastatin,
antibiotics and of course Heparin.
Clot retraction -CORRECTANSWER the consolidation or tightening of the fibrin clot
pulls the edges of the damaged vessel close together, allowing for repair of the vessel
lining.
,Clot dissolution -CORRECTANSWER fibrinolysis occurs through conversion of
plasminogen to plasmin by tissue plasminogen activator (tPA), which is released from
damaged endothelial cells. This conversion results in digestion of fibrin fibers within the
clot and the production of fibrin degradation products.... Clot dissolves.
Immune thrombocytopenia -CORRECTANSWER was formally called idiopathic
thrombocytopenia purpura. ITP is the most common thrombocytopenic disorder among
children and often follows an upper respiratory infection.
Thrombotic Thrombocytopenic -CORRECTANSWER rare and caused by a deficiency
of the gene responsible for severing large von Willebrand factor proteins. The
unchecked platelet aggregation results in microvascular occlusions...end organ failure
Spontaneous bleeding from platelet disorders -CORRECTANSWER Most often involves
small vessels of mucous membranes and skin, common sites are nose, mouth, GI,
uterine
Cutaneous bleeding -CORRECTANSWER seen as pinpoint hemorrhages (petechiae),
or purple areas of bruising (purpura)
Petechiae -CORRECTANSWER Occur almost exclusively in conditions of platelet
deficiency, not dysfunction
, 120 days -CORRECTANSWER RBC lifespan
Spleen -CORRECTANSWER Breaks down RBC
5 years -CORRECTANSWER Almost all bones produce RBCS to maintain growth rate
until this age
Red bone marrow -CORRECTANSWER RBCS produced here after birth
20 years -CORRECTANSWER Age when red cell production takes place mainly in the
membranous bones of the vertebrae, sternum, ribs, and pelvis and red marrow changes
to fatty yellow due to decreased activity
Iron and amino acids -CORRECTANSWER Degradation products recycled when RBCS
are broken down
Hematocrit -CORRECTANSWER Measures the volume of red cell mass in 100 mL of
plasma volume
Transfusion reaction symptoms -CORRECTANSWER •Sensation of heat along the vein
where the blood is being infused
•Flushing of the face
•Urticaria/rash, headache, pain in the lumbar area
