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The chance of developing colorectal cancer increases markedly
after age _____. Roughly 9 out of 10 people diagnosed with
colorectal cancer are at least ____ years old. - ANSWER-50
Other risk factors for the development of colorectal cancer
include: - ANSWER-Racial and ethnic backgrounds (African
Americans and Jews of Eastern European descent (Ashkenazi
Jews) have highest incidence)
Diet high in red and processed meats
Physical inactivity, obesity
Type 2 diabetes
Family history of colon cancer or inflammatory bowel disease
Inherited familial syndromes (FAP, HNPCC)
Treatment regiment for Colorectal Cancer - ANSWER-FOLFOX6
Oxaliplatin 100mg/m2 and Leucovorin 400 mg/m2 IV over 2-
hours, then
5-fluorouracil (5-FU) 400 mg/m2 IV bolus, followed by
5-FU 3,000 mg/m2 IV by continuous infusion over 46 hours
Which of the following is a unique side effect that occurs with
the agent oxaliplatin? - ANSWER-Cold sensory neuropathy
,Cold sensory neuropathy symptoms - ANSWER-Transient
paresthesia
Dysesthesia and hypoesthesia in the hands, feet, perioral area,
or throat.
Jaw spasm
Abnormal tongue sensation
Dysarthria
Eye pain, and a feeling of chest pressure have also been
observed
Effective treatments for peripheral neuropathy - ANSWER-
Duloxetine
Gabapentin and Opioid Combination
Thinking that this is early mucositis, which of the following
should the nurse instruct Mr. Patterson to do to help his
symptoms? - ANSWER-Per the ONS PEP resources for
mucositis (https://www.ons.org/practice-
resources/pep/mucositis), of the listed answers, oral care
protocol would be what the nurse needs to ensure Mr.
Patterson is doing at home for his early mucositis to prevent it
from worsening.
Which of the following of Mr. Patterson's lifestyle factors put
him at the most risk for developing mucositis? - ANSWER-Risk
factors for mucositis that are not from the agents themselves
include the following: dental disease and poor oral hygiene, ill-
fitting dentures, advanced age and youth age, history of
alcohol and tobacco use, poor nutrition, intake of irritating
, foods (spicy or acidic foods), and dehydration (Information
from the chemo/bio guidelines page 214-215). Mr. P. has both a
poor diet and also uses tobacco (both chewing tobacco and
cigarettes) and alcohol. The use of tobacco products is a big
risk factor for development of mucositis.
Recommended and effective care in mucositis - ANSWER-
Recommended for Practice:
Cryotherapy
Low Level Laser Therapy in Patients Undergoing Hematopoietic
Cell Transplantation
Low Level Laser Therapy in Patients With Head and Neck
Cancer
Oral Care Protocol
Sodium Bicarbonate
Likely to Be Effective:
Benzydamine for Patients Receiving Combination
Chemotherapy and Radiation Therapy
Benzydamine for Radiation-Related Mucositis
Lactobacillus Lozenges
Palifermin for Patients Receiving Chemotherapy and Radiation
for Head and Neck Cancer
Palifermin with High-Dose Chemotherapy and/or Hematopoietic
Cell Transplantation
Which of the following are recommended as standard PPE
when there is any potential exposure for hazardous drugs?