ASCP-Chemistry section Exam with accurate detailed || || || || || ||
solutions
Aldosterone is released by the adrenal cortex upon stimulation by:
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A. Renin
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B. Angiotensinogen
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C. Angiotenisinogen I
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D. Angiotensinogen II - ✔✔D. Angiotensinogen II
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Clinical Assays for tumor markers are most important for:
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A. screening for the presence of cancer
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B. monitoring the course of known cancer
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C. confirming the absence of disease
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D. identifying patients at risk for cancer - ✔✔B. Monitoring the course of known cancer
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Detection of which of the following substances is most useful to monitor the course of a
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patient with testicular cancer?
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A. alpha-fetoprotein
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B. carcinoembryonic antigen
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C. prolactin
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D. testosterone - ✔✔A. alpha-fetoprotein
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Increased concentrations of alpha-fetoprotein (AFP) in adults are most characteristically
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associated with: ||
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A. hepatocellular carcinoma
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B. alcoholic cirrhosis
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C. chronic active hepatitis
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D. multiple myeloma - ✔✔A. hepatocellular carcinoma
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Carcinoembryonic antigen (CEA) is most likely to be produced in a maignancy involving || || || || || || || || || || || || ||
the:
A. Brain
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B. Testes
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C. Bone
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D. Colon - ✔✔D. Colon
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Which of the following is useful in the detection an management of carcinoma of the
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prostate?
A. total prostate-specific antigen
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B. prostatic acid phosphatase
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C. human chorionic gonadotropin
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D. alpha-fetoprotein - ✔✔A. total prostate-specific antigen
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Which of the following statements most correctly describes the utility of clinical laboratory
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assays for tumor markers?
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A. tumor markers are useful to screen asymptomatic patients for tumors
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B. tumor markers are highly specific
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C. tumor markers indicate the likelihood of an individual developing a tumor
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D. tumors are useful in tracking the efficacy of treatment - ✔✔D. tumors are useful in
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tracking the efficacy of treatment|| || || ||
Cancer antigen 125 (CA 125) is a tumor marker associated with:
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A. breast carcinoma
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B. colon cancer
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C. lung cancer
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D. ovarian and endometrial carcinoma - ✔✔D. ovarian and endometrial carcinoma
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In addition to carcinoma of the prostate, elevated prostate-specific antigen (PSA) can occur
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due to: ||
A. aspirin therapy
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B. exogenous steroid use
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C. benign prostatic hyperplasia
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D. statin therapy (cholesterol lowering drugs) - ✔✔C. benign prostatic hyperplasia
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A drug has a half-life of 6 hours. If a dose is given every 6 hours, a steady-state drug level
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would usually be achieved in:
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A. 3-5 hours
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B. 10-12 hours
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C. 24-42 hours
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D. 48-50 hours - ✔✔C. 24-42 hours
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