Advanced Pharmacology Final Exam Review questions with verified || || || || || || || ||
detailed answers ||
Why are nitrate-free periods every 24 hours necessary for the patient on nitroglycerin
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therapy? - ✔✔To inhibit the development of tolerance
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What does a low level of thyroid-stimulating hormone indicate? - ✔✔Hyperthroidism
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What would be the best option to treat a newly diagnosed patient with a low TSH level
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with? - ✔✔Propanolol (Inderal)
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Spironoaldactone (Aldactone) has what mechanism of action (MOA)? - ✔✔Aldosterone || || || || || || || || || ||
antagonist
Heparin exerts its therapeutic action by what? - ✔✔Upregulating the activity of one of the
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body's natural anticoagulant molecules, antithrombin III
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What physiologic action happens when the offending drug is administered during an
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anaphylactic reaction. - ✔✔Mast cells liberate large doses of histamine.
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What are two systemic psoriasis medications? - ✔✔Photo-therapy and topical
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corticosteroids
What is the first choice of drug therapy for the majority of patients with uncomplicated
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stage I hypertension? - ✔✔Thiazide diuretics
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What is the effect of cardiac glycosides? - ✔✔Digitalis glycosides have a negative
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chronotropic effect on the cardiac muscle cells. || || || || || ||
, 2
Amenorrhea is the most common side effect of which birth control medication? -
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✔✔Medroxyprogesterone (Depo-Provera) ||
What is an anti-hypertensive agent which competes with epinephrine for available beta-
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receptor sites? - ✔✔Atenolol (Tenormin)
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What type of action does nitrates have on the body? - ✔✔Reduction in systemic venous
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tone.
What is the recommended level of low-density lipoprotein cholesterol (LDL) for patients
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with known coronary artery disease? - ✔✔100mg/dl or less.
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What is the MOA of group IV anti-dysrhythmia drugs? - ✔✔Depressing phase 4
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depolarization and lengthening phases 1 and 2 repolarization. || || || || || || ||
Which drug therapy should be used to lower the serum concentration of thyroid hormones
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and re-establish eumetabolic state in a patient with Graves' disease? - ✔✔Anti-thyroid
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drugs.
Which type of diuretic would be used for a stage I hypertension in a patient with renal
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insufficiency? - ✔✔Loop diuretic. || || ||
What drug should be considered as first-line therapy for a client with hypertension and
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heart failure? - ✔✔Enalapril (Vasotec)
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Which drug is considered safe for hypertension treatment during pregnancy? -
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✔✔Methyldopa (Aldomet) ||