2
Pharmacotherapeutics Final Exam with verified detailed solutions || || || || || ||
pharmacodynamics - ✔✔study of the mechanisms of action of drugs within the body and || || || || || || || || || || || || || ||
how drugs produce their effects in the body
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pharmacokinetics - ✔✔study of drug actions as they move through the body; the way the
|| || || || || || || || || || || || || || ||
body absorbs, distributes, metabolizes and excretes drugs; mathematical study of drugs
|| || || || || || || || || || ||
based on time and dose
|| || || ||
pharmacology - ✔✔study of biologically active compounds, how they react in the body and
|| || || || || || || || || || || || || ||
how the body reacts to them
|| || || || ||
pharmacotherapeutics - ✔✔study of drugs used to prevent, treat or diagnose disease || || || || || || || || || || ||
Agonists - ✔✔drugs enhance the generation, transmission or receiving of the signal
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partial agonist - ✔✔drugs diminish the generation, transmission or receiving of the signal
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antagonist - ✔✔drugs block the generation, transmission or receiving of the signal
|| || || || || || || || || || ||
affinity - ✔✔attraction between a drug and receptor
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drug potency - ✔✔amount of drug required to produce a therapeutic response
|| || || || || || || || || || ||
enteral - ✔✔enters the body through the GI tract
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, 2
parenteral - ✔✔enters the body through a different means, i.e. injected into the veins,
|| || || || || || || || || || || || || ||
arteries, muscles, spinal cord, inhaled or transdermally through the skin
|| || || || || || || || ||
first pass effect - ✔✔drugs absorbed through the stomach and small intestine must pass
|| || || || || || || || || || || || || ||
through the liver before circulating systemically
|| || || || ||
drug distribution - ✔✔influenced by tissue permeability, blood flow, plasma proteins
|| || || || || || || || || || ||
binding
drug storage sites - ✔✔adipose tissue, bone, muscle, organs
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biotransformation of drugs - ✔✔chemical changes that occur in the drug following || || || || || || || || || || || ||
administration
loop diuretics - ✔✔increase excretion of sodium and water, for control of hypertension and
|| || || || || || || || || || || || || ||
fluid retention (you will pee alot)
|| || || || ||
loop diuretics indications - ✔✔treats edema associated with heart failure, hypertension,
|| || || || || || || || || || ||
renal impairment and hypertensive crisis
|| || || ||
common loop diuretics - ✔✔Bumetanide (Bumex), Furosemide (Lasix), Torsemide
|| || || || || || || || ||
(Demadex)
adverse reactions of loop diuretics - ✔✔metabolic and electrolyte disturbances,
|| || || || || || || || || ||
hypochloremic alkaosis, hyperglycemia, hyperuricemia, hypomagnesemia, ototoxicity,
|| || || || || ||
tinnitus (Diuretic) ||
potassium sparing diuretics - ✔✔less potent than other diuretics, protects against potassium
|| || || || || || || || || || ||
loss
||
Pharmacotherapeutics Final Exam with verified detailed solutions || || || || || ||
pharmacodynamics - ✔✔study of the mechanisms of action of drugs within the body and || || || || || || || || || || || || || ||
how drugs produce their effects in the body
|| || || || || || ||
pharmacokinetics - ✔✔study of drug actions as they move through the body; the way the
|| || || || || || || || || || || || || || ||
body absorbs, distributes, metabolizes and excretes drugs; mathematical study of drugs
|| || || || || || || || || || ||
based on time and dose
|| || || ||
pharmacology - ✔✔study of biologically active compounds, how they react in the body and
|| || || || || || || || || || || || || ||
how the body reacts to them
|| || || || ||
pharmacotherapeutics - ✔✔study of drugs used to prevent, treat or diagnose disease || || || || || || || || || || ||
Agonists - ✔✔drugs enhance the generation, transmission or receiving of the signal
|| || || || || || || || || || ||
partial agonist - ✔✔drugs diminish the generation, transmission or receiving of the signal
|| || || || || || || || || || || ||
antagonist - ✔✔drugs block the generation, transmission or receiving of the signal
|| || || || || || || || || || ||
affinity - ✔✔attraction between a drug and receptor
|| || || || || || ||
drug potency - ✔✔amount of drug required to produce a therapeutic response
|| || || || || || || || || || ||
enteral - ✔✔enters the body through the GI tract
|| || || || || || || ||
, 2
parenteral - ✔✔enters the body through a different means, i.e. injected into the veins,
|| || || || || || || || || || || || || ||
arteries, muscles, spinal cord, inhaled or transdermally through the skin
|| || || || || || || || ||
first pass effect - ✔✔drugs absorbed through the stomach and small intestine must pass
|| || || || || || || || || || || || || ||
through the liver before circulating systemically
|| || || || ||
drug distribution - ✔✔influenced by tissue permeability, blood flow, plasma proteins
|| || || || || || || || || || ||
binding
drug storage sites - ✔✔adipose tissue, bone, muscle, organs
|| || || || || || || ||
biotransformation of drugs - ✔✔chemical changes that occur in the drug following || || || || || || || || || || || ||
administration
loop diuretics - ✔✔increase excretion of sodium and water, for control of hypertension and
|| || || || || || || || || || || || || ||
fluid retention (you will pee alot)
|| || || || ||
loop diuretics indications - ✔✔treats edema associated with heart failure, hypertension,
|| || || || || || || || || || ||
renal impairment and hypertensive crisis
|| || || ||
common loop diuretics - ✔✔Bumetanide (Bumex), Furosemide (Lasix), Torsemide
|| || || || || || || || ||
(Demadex)
adverse reactions of loop diuretics - ✔✔metabolic and electrolyte disturbances,
|| || || || || || || || || ||
hypochloremic alkaosis, hyperglycemia, hyperuricemia, hypomagnesemia, ototoxicity,
|| || || || || ||
tinnitus (Diuretic) ||
potassium sparing diuretics - ✔✔less potent than other diuretics, protects against potassium
|| || || || || || || || || || ||
loss
||