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Pharmacotherapeutics Final Exam with verified detailed solutions

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Pharmacotherapeutics Final Exam with verified detailed solutions

Institution
Pharmacotherapeutics
Course
Pharmacotherapeutics

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2



Pharmacotherapeutics Final Exam with verified detailed solutions || || || || || ||




pharmacodynamics - ✔✔study of the mechanisms of action of drugs within the body and || || || || || || || || || || || || || ||




how drugs produce their effects in the body
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pharmacokinetics - ✔✔study of drug actions as they move through the body; the way the
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body absorbs, distributes, metabolizes and excretes drugs; mathematical study of drugs
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based on time and dose
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pharmacology - ✔✔study of biologically active compounds, how they react in the body and
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how the body reacts to them
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pharmacotherapeutics - ✔✔study of drugs used to prevent, treat or diagnose disease || || || || || || || || || || ||




Agonists - ✔✔drugs enhance the generation, transmission or receiving of the signal
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partial agonist - ✔✔drugs diminish the generation, transmission or receiving of the signal
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antagonist - ✔✔drugs block the generation, transmission or receiving of the signal
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affinity - ✔✔attraction between a drug and receptor
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drug potency - ✔✔amount of drug required to produce a therapeutic response
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enteral - ✔✔enters the body through the GI tract
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, 2


parenteral - ✔✔enters the body through a different means, i.e. injected into the veins,
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arteries, muscles, spinal cord, inhaled or transdermally through the skin
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first pass effect - ✔✔drugs absorbed through the stomach and small intestine must pass
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through the liver before circulating systemically
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drug distribution - ✔✔influenced by tissue permeability, blood flow, plasma proteins
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binding



drug storage sites - ✔✔adipose tissue, bone, muscle, organs
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biotransformation of drugs - ✔✔chemical changes that occur in the drug following || || || || || || || || || || || ||




administration



loop diuretics - ✔✔increase excretion of sodium and water, for control of hypertension and
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fluid retention (you will pee alot)
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loop diuretics indications - ✔✔treats edema associated with heart failure, hypertension,
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renal impairment and hypertensive crisis
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common loop diuretics - ✔✔Bumetanide (Bumex), Furosemide (Lasix), Torsemide
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(Demadex)



adverse reactions of loop diuretics - ✔✔metabolic and electrolyte disturbances,
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hypochloremic alkaosis, hyperglycemia, hyperuricemia, hypomagnesemia, ototoxicity,
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tinnitus (Diuretic) ||




potassium sparing diuretics - ✔✔less potent than other diuretics, protects against potassium
|| || || || || || || || || || ||




loss
||

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Institution
Pharmacotherapeutics
Course
Pharmacotherapeutics

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