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Pharmacotherapeutics Exam 3 with verified detailed solutions

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Pharmacotherapeutics Exam 3 with verified detailed solutions

Institution
Pharmacotherapeutics
Course
Pharmacotherapeutics

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2



Pharmacotherapeutics Exam 3 with verified detailed solutions || || || || || ||




A patient with systemic lupus erythematosus is prescribed
|| || || || || || ||




prednisone. It is most important for the nurse to monitor the patient for what?
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A. Hypotension
||




B. Elevated potassium levels
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C. Neck and back pain
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D. Hypoglycemia - ✔✔Answer: C
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Rationale: Neck and back pain from a vertebral compression fracture may occur because of
|| || || || || || || || || || || || || ||




the development of osteoporosis as a result of glucocorticoid therapy. Other possible adverse
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effects of prednisone include hypertension, hypokalemia, and hyperglycemia.
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*Reference Ch. 72 - Gluocorticoids* || || || ||




A patient has been prescribed pharmacologic doses of glucocorticoids. It is most important
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for the nurse to teach the patient to do what?
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A. Increase intake of dietary sodium.
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B. Take antibiotics to prevent infection.
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C. Never abruptly withdraw therapy.
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D. Have an eye examination every year. - ✔✔Answer: C
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Rationale: Abrupt withdrawal of glucocorticoids may cause adrenal insufficiency or an
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adrenal crisis. Infection should be prevented, but the use of antibiotics without a known
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infection is inappropriate. Sodium intake should be restricted while the patient is taking
|| || || || || || || || || || || || ||




glucocorticoids. Eye examinations are recommended every 6 months for patients on || || || || || || || || || || ||




glucocorticoid therapy. ||

,2




*Reference Ch. 72 - Glucocorticoids* || || || ||




A patient has been receiving long-term prednisone therapy for treatment of rheumatoid
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arthritis. The chart indicates that the patient has developed Cushing's syndrome. When
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performing a physical assessment, the nurse anticipates finding all but which manifestation
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of Cushing's syndrome?
|| ||




A. Hypoglycemia
||




B. Muscle weakness
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C. Glucosuria
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D. "Buffalo hump" - ✔✔Answer: A
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Rationale: Cushing's syndrome is manifested by hyperglycemia, glycosuria, fluid and
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electrolyte disturbances, osteoporosis, muscle weakness, cutaneous striations, and lowered
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resistance to infection. Redistribution of fat produces a "potbelly," "moon face," and "buffalo
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hump."



*Reference Ch. 72 - Glucocorticoids* || || || ||




A patient with rheumatoid arthritis has been taking high-dose aspirin and complains of
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gastric upset and pain. What does the nurse anticipate will be prescribed for this patient?
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A. Taking a lower dose of aspirin
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B. Biweekly injections of methotrexate [Rheumatrex]
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C. Obtaining a prescription for celecoxib [Celebrex]
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D. Daily drug therapy with prednisone - ✔✔Answer: C
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Rationale: If aspirin causes gastrointestinal upset or pain, a cyclooxygenase-2 (COX-2)
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inhibitor (celecoxib) should be considered. Methotrexate is administered once a week. Daily
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, 2


prednisone therapy is not indicated; prednisone is usually administered for exacerbations
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and as short-term therapy.
|| || ||




*Reference Ch. 73 - Rheumatoid Arthritis* || || || || ||




A patient with rheumatoid arthritis is prescribed methotrexate [Rheumatrex]. The nurse
|| || || || || || || || || || ||




will expect to observe therapeutic effects with this drug in which time period?
|| || || || || || || || || || || ||




A. 3 to 7 days
|| || || ||




B. 3 to 6 weeks
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C. 3 to 4 months
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D. 1 to 2 years - ✔✔Answer: B
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Rationale: Methotrexate acts faster than all other disease-modifying antirheumatic drugs.
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Therapeutic effects may develop in 3 to 6 weeks. || || || || || || || ||




*Reference Ch. 73 - Rheumatoid Arthritis* || || || || ||




A patient with acute gouty arthritis requests information on the preferred drug to take to
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treat a painful flare-up. The nurse should recommend which medication?
|| || || || || || || || ||




A. Allopurinol
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B. Febuxostat
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C. Probenecid
||




D. Naproxen - ✔✔Answer: D
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Rationale: NSAIDs and glucocorticoids are preferred drugs for treating acute gouty attacks.
|| || || || || || || || || || || ||




Benefits derive mainly from anti-inflammatory actions. Four drugs—allopurinol,
|| || || || || || || ||




febuxostat, probenecid, and pegloticase—are used long term to prevent gouty attacks.
|| || || || || || || || || || ||




Benefits derive from lowering plasma uric acid levels. These drugs lack anti-inflammatory
|| || || || || || || || || || || ||

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Institution
Pharmacotherapeutics
Course
Pharmacotherapeutics

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