NSG 533 Advanced Pharmacology Test 1 Week 4
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Which of the following is a dangerous combination?
A. MAOI-lorazepam
B. MAOI-acetaminophen
C. MAOI-meperidine
D. MAOI-ziprasidone - Answer-C
A 23-year-old married white woman comes to the
outpatient psychiatric clinic
complaining of decreased sleep, decreased appetite,
decreased concentration, depressed
mood, thoughts of death, and lack of interest in activities
for 6 weeks' duration. She has
no history of psychiatric illness and takes no medications
except for Ortho-Tri Cyclen Lo
daily. Based upon the patients symptoms, choose the best
medication to treat this patient.
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A. Nefazodone 100 mg po twice daily
B. Paroxetine 20 mg po daily
C. St. John's wort 300 mg po three times daily
D. Amitriptyline 25 mg at bedtime - Answer-B
A 36-year-old man is admitted to the hospital for a severe
methicillin-resistant Staphylococcus aureus diabetic foot
infection and is started on linezolid 600 mg IV every 12
hours. His medication profile includes paroxetine 40 mg
every morning, trazodone 100 mg at bedtime as needed
for sleep, and metformin 1000 mg po twice daily. After 3
days on these medications, the patient becomes agitated,
confused, and diaphoretic and develops myoclonic jerks.
Which of the following is the most likely diagnosis?
A. Overdose of metformin
B. Bacterial meningitis
C. Neuroleptic malignant syndrome
D. Serotonin syndrome - Answer-D
A 46-year-old woman presents to the psychiatric
outpatient clinic for follow-up treatment of major
depression. She is currently on paroxetine 10 mg at
bedtime, which she started taking 2 months ago when
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admitted to the psychiatric hospital for suicidal ideation.
During the interview, she says that she does not think the
medication is working because she is just as depressed as
she was before taking the medication and has recently
started drinking eight to 10 beers daily to alleviate the
depression. Before this episode, she was
sober for 4 years. Which of the following treatment
strategies would be the appropriate choice for this patient?
A. Stop the paroxetine and start nefazodone 100 mg po
twice daily
B. Increase the dose of paroxetine to 20 mg po at bedtime
C. Stop the paroxetine and start duloxetine 20 mg/day
D. Continue the paroxetine at them same dose for a
longer period of time to evaluate
whether she will res - Answer-B
Which of the following SSRIs requires up to a 5-week
washout period because of the
long half-life of its potent active metabolite?
A. Escitalopram
B. Fluvoxamine
C. Fluoxetine