NCLEX UWORLD PHARMACOLOGY EXAM
STUDY GUIDE QUESTIONS WITH ANSWERS
LATEST UPDATE
Lithium --ANSWER---prescribed for bipolar disorder
-if kidney issues are present (including dehydration) question prescription
LITHIUM TOXICITY
-n/v, diarrhea, confusion, agitation
SE
-drowsiness
-weight gain
-dry mouth
-avoid sodium depletion
-eat regular diet
-adequate fluids
-avoid NSAIDs
-takes up to 3 weeks to be effective
Page 1 of 24
,THERAPEUTIC RANGE
-0.6-1.2
Tricyclic Antidepressants --ANSWER--TYLINE/PRAMINE
Amitriptyline, nortriptyline, imipramine, desipramine, clomipramine, doxepin,
amoxapine.
SE
-constipation
-restlessness
-dizziness
MAOIs --ANSWER--isocarboazid, phenelyzene, tranylcpromine
-avoid tyramine containing foods (aged cheeses, cured meats, beers, overripe
fruit)
SSRIs --ANSWER--XETINE/PRAM/ALINE
fluoxetine, paroxetine, sertaline, citalopram
Page 2 of 24
, SEROTONIN SYNDROME
-agitation
-confusion
-tachycardia
-diaphoresis
-tremors
-hyperreflexia
-insomnia
-sexual dysfunction
SE
-weight gain (long term use)
-increased suicide risk at beginning of therapy (if reporting increase in energy
and no change in depression further assessment is needed)
-sexual dysfunction
-serotonin syndrome
*SE should subside in 3 months
Antidepressant General Info --ANSWER---do not immediately stop
medications
-takes weeks to take effect
-do not take these drugs together
Page 3 of 24
STUDY GUIDE QUESTIONS WITH ANSWERS
LATEST UPDATE
Lithium --ANSWER---prescribed for bipolar disorder
-if kidney issues are present (including dehydration) question prescription
LITHIUM TOXICITY
-n/v, diarrhea, confusion, agitation
SE
-drowsiness
-weight gain
-dry mouth
-avoid sodium depletion
-eat regular diet
-adequate fluids
-avoid NSAIDs
-takes up to 3 weeks to be effective
Page 1 of 24
,THERAPEUTIC RANGE
-0.6-1.2
Tricyclic Antidepressants --ANSWER--TYLINE/PRAMINE
Amitriptyline, nortriptyline, imipramine, desipramine, clomipramine, doxepin,
amoxapine.
SE
-constipation
-restlessness
-dizziness
MAOIs --ANSWER--isocarboazid, phenelyzene, tranylcpromine
-avoid tyramine containing foods (aged cheeses, cured meats, beers, overripe
fruit)
SSRIs --ANSWER--XETINE/PRAM/ALINE
fluoxetine, paroxetine, sertaline, citalopram
Page 2 of 24
, SEROTONIN SYNDROME
-agitation
-confusion
-tachycardia
-diaphoresis
-tremors
-hyperreflexia
-insomnia
-sexual dysfunction
SE
-weight gain (long term use)
-increased suicide risk at beginning of therapy (if reporting increase in energy
and no change in depression further assessment is needed)
-sexual dysfunction
-serotonin syndrome
*SE should subside in 3 months
Antidepressant General Info --ANSWER---do not immediately stop
medications
-takes weeks to take effect
-do not take these drugs together
Page 3 of 24
