ONS ONCC CHEMO RENEWAL EXAM
2026 QUESTIONS AND ANSWERS
GRADED A+ 100% VERIFIED
When receiving chemotherapy in the home (in Mr. Patterson..'s case he is getting
continuous 5-FU) it is recommended to send the patient home with and instruct
them on the use of a spill kit (see Figure 13 from the Guidelines). Other important
things to include in your education is that everyone, not just caregivers, should
wear gloves when touching the chemotherapy or anything soiled by
chemotherapy. Visitors are welcome and encouraged when patients are going
through chemotherapy. Hugging and kissing are safe post chemotherapy. Sexual
activity is usually considered safe as well with the use of barrier protection.
However, it is recommended that patients discuss this issue with their physician or
nurse first to discuss specific precautions that may be necessary. - Correct Answer
-Which of the following is of utmost importance to include in your education to
Mr. Patterson since he will be receiving HDs at home (continuous 5-FU)?
Serum Creatinine
The estimated glomerular filtration rate (eGFR) is required for the carboplatin
dose calculation. Serum creatinine is used to determine the eGFR. The eGFR is
needed to calculate the carboplatin dose. To determine the eGFR the following is
needed: age of patient, weight, gender, and serum creatinine. The most
commonly used formula to calculate the GFR in the United States is the Cockcroft-
Gault formula . A 24-hour urine can also be used to determine GFR if the patient
,has one. - Correct Answer -Which of the following lab results must you have to
review the dose calculation of Mrs. Kearns's carboplatin?
Paclitaxel is mixed in a mineral-oil like solvent that can cause infusion related
hypersensitivity reactions. Premedication should be given to prevent this from
occurring. All patients should be pretreated with corticosteroids,
diphenhydramine, and H2 antagonists. Paclitaxel is an irritant and potential
vesicant. Therefore it is very important for patient to receive education about
symptoms to report (i.e. pain, erythema, redness). To prevent severe
myelosuppression, paclitaxel should always be given prior to platinum-containing
medications. Paclitaxel should be administered via a 0.3 micron in-line filter using
a glass bottle or non-PVC bag and tubing. - Correct Answer -Mrs. Kearns's orders
seem appropriate and correct according to you and the other RNs calculations.
She is a little nervous but ready to begin her first cycle of chemotherapy.
Which of the following is true related to paclitaxel treatment?
Although hypersensitivity and infusion reactions can occur at any time and
potentially with any chemotherapy agent, there are certain agents that have a
higher risk of causing a reaction. For some agents, the reaction is more likely to
occur after they have received a few doses and have already been exposed to the
same agent. On the other hand, there are agents where the hypersensitivity
reactions can occur almost immediately on exposure. Reactions to platinum drugs
(e.g., carboplatin, cisplatin, oxaliplatin) usually occur after multiple treatments.
However, reactions caused by taxanes (e.g., paclitaxel, docetaxel) usually occur
within the first hour of the first or second treatment. Reactions to monoclonal
antibodies like rituximab and cetuximab usually occur with the first treatment as
, well. (Information from Zetka article) - Correct Answer -Which of the following
agents would you anticipate a hypersensitivity reaction more often occurring after
the patient has already received several doses?
Carboplatin's elimination by the kidneys occurs in a reliable manner that makes
AUC the optimal method for dosing the drug. Basically, AUC is a method of
expressing the intended exposure to the drug over time. Verification of
carboplatin doses can be daunting if institutional policies are not clear regarding
which formula to use under what conditions. In the absence of clear institutional
direction, documentation in the orders and plan of care must state the process
used to determine the intended dose. - Correct Answer -Why use AUC instead of
BSA for carboplatin dosing?
a. Stop the paclitaxel infusion - Correct Answer -Mrs. Kearns is receiving her first
dose of paclitaxel and about 20 minutes into the infusion, you notice that she
begins to start clearing her throat a lot. She also states that she is having some
lower back pain. You decide that you will take another set of vital signs. While you
are waiting for the monitor to reveal her blood pressure, she begins to breathe
heavier and appears short of breath.
What is the first/immediate thing you need to do for Mrs. Kearns?
Mr. Rylan is receiving doxorubicin as part of his chemotherapy regimen. The
patient's ejection fraction should be tested prior to starting doxorubicin. Periodic
monitoring is also suggested in addition to testing ejection fraction one year post
2026 QUESTIONS AND ANSWERS
GRADED A+ 100% VERIFIED
When receiving chemotherapy in the home (in Mr. Patterson..'s case he is getting
continuous 5-FU) it is recommended to send the patient home with and instruct
them on the use of a spill kit (see Figure 13 from the Guidelines). Other important
things to include in your education is that everyone, not just caregivers, should
wear gloves when touching the chemotherapy or anything soiled by
chemotherapy. Visitors are welcome and encouraged when patients are going
through chemotherapy. Hugging and kissing are safe post chemotherapy. Sexual
activity is usually considered safe as well with the use of barrier protection.
However, it is recommended that patients discuss this issue with their physician or
nurse first to discuss specific precautions that may be necessary. - Correct Answer
-Which of the following is of utmost importance to include in your education to
Mr. Patterson since he will be receiving HDs at home (continuous 5-FU)?
Serum Creatinine
The estimated glomerular filtration rate (eGFR) is required for the carboplatin
dose calculation. Serum creatinine is used to determine the eGFR. The eGFR is
needed to calculate the carboplatin dose. To determine the eGFR the following is
needed: age of patient, weight, gender, and serum creatinine. The most
commonly used formula to calculate the GFR in the United States is the Cockcroft-
Gault formula . A 24-hour urine can also be used to determine GFR if the patient
,has one. - Correct Answer -Which of the following lab results must you have to
review the dose calculation of Mrs. Kearns's carboplatin?
Paclitaxel is mixed in a mineral-oil like solvent that can cause infusion related
hypersensitivity reactions. Premedication should be given to prevent this from
occurring. All patients should be pretreated with corticosteroids,
diphenhydramine, and H2 antagonists. Paclitaxel is an irritant and potential
vesicant. Therefore it is very important for patient to receive education about
symptoms to report (i.e. pain, erythema, redness). To prevent severe
myelosuppression, paclitaxel should always be given prior to platinum-containing
medications. Paclitaxel should be administered via a 0.3 micron in-line filter using
a glass bottle or non-PVC bag and tubing. - Correct Answer -Mrs. Kearns's orders
seem appropriate and correct according to you and the other RNs calculations.
She is a little nervous but ready to begin her first cycle of chemotherapy.
Which of the following is true related to paclitaxel treatment?
Although hypersensitivity and infusion reactions can occur at any time and
potentially with any chemotherapy agent, there are certain agents that have a
higher risk of causing a reaction. For some agents, the reaction is more likely to
occur after they have received a few doses and have already been exposed to the
same agent. On the other hand, there are agents where the hypersensitivity
reactions can occur almost immediately on exposure. Reactions to platinum drugs
(e.g., carboplatin, cisplatin, oxaliplatin) usually occur after multiple treatments.
However, reactions caused by taxanes (e.g., paclitaxel, docetaxel) usually occur
within the first hour of the first or second treatment. Reactions to monoclonal
antibodies like rituximab and cetuximab usually occur with the first treatment as
, well. (Information from Zetka article) - Correct Answer -Which of the following
agents would you anticipate a hypersensitivity reaction more often occurring after
the patient has already received several doses?
Carboplatin's elimination by the kidneys occurs in a reliable manner that makes
AUC the optimal method for dosing the drug. Basically, AUC is a method of
expressing the intended exposure to the drug over time. Verification of
carboplatin doses can be daunting if institutional policies are not clear regarding
which formula to use under what conditions. In the absence of clear institutional
direction, documentation in the orders and plan of care must state the process
used to determine the intended dose. - Correct Answer -Why use AUC instead of
BSA for carboplatin dosing?
a. Stop the paclitaxel infusion - Correct Answer -Mrs. Kearns is receiving her first
dose of paclitaxel and about 20 minutes into the infusion, you notice that she
begins to start clearing her throat a lot. She also states that she is having some
lower back pain. You decide that you will take another set of vital signs. While you
are waiting for the monitor to reveal her blood pressure, she begins to breathe
heavier and appears short of breath.
What is the first/immediate thing you need to do for Mrs. Kearns?
Mr. Rylan is receiving doxorubicin as part of his chemotherapy regimen. The
patient's ejection fraction should be tested prior to starting doxorubicin. Periodic
monitoring is also suggested in addition to testing ejection fraction one year post
