Page 1 of 44
UWORLD STEP 2 SELF ASSESMENT 1 EXAM
NEWEST 2026 ACTUAL EXAM QUESTIONS AND
CORRECT DETAILED ANSWERS (VERIFIED
ANSWERS) ALL ANSWERED {190 Q & A}
ALREADY GRADED A+ | BRAND NEW! | 100%
GUARANTEED PASS
What is the treatment of primary hyperaldosteronism if teh
cause is bilateral adrenal hyperplasia? - ✔✔✔ correct answer >
aldonsterone antagonist
- spironolactone
- epleronone
If someone is suspicious for epithelial ovarian carcinoma and you
see pleural effusions and nodularity of the rectovaginal septum,
what are you thinking? - ✔✔✔ correct answer > Metastatic spread
in hypercalcemia of malignancy (small cell carcinoma) the
calcium levels can rise very fast, what are the consequences of
this compared to primary hyperparathyroidism? - ✔✔✔ correct
answer > Hypercalcemia of malignancy causes a very rapid rise in
calcium to a very high level (>12). This causes neurologic
symptoms such as lethargy, coma, delerium, and confusion
,Page 2 of 44
Hypercalcemia of primary hyperparathyroidism causes a rise in
calcium but not >12 usually and does not cause as pronounced
neurological symptoms
what are some early and late complications of Roux-en-Y gastric
bypass surgery? - ✔✔✔ correct answer > Early
- Anastomotic leak (sepsis)
- Bowel ischemia (diffuse abdominal pain)
LAte
- Anastomotic stricture (dysphagia, bowel obstruction
- CHOLECYSTITIS
- Dumping syndrome (Diarrhea,vomiting, crampy abdominal pain,
flushing, palpitations)
why do people who under go Roux-en-Y gastric bypass surgery
get gallstones and cholecystitis? - ✔✔✔ correct answer > because
they lose a lot of weight fast. which causes the gallstones
why do people who under go roux-en-Y gastric bypass surgery
get dumping syndrome? - ✔✔✔ correct answer > because of rapid
gastric emptying
,Page 3 of 44
Which drugs can cause acute interstitial nephritis? - ✔✔✔ correct
answer > NSAIDS, PPI,
What will a urine microscopy show in acute interstitial nephritis?
- ✔✔✔ correct answer > eosinophils
What drugs cause acute tubular necrosis? - ✔✔✔ correct answer >
Aminoglycosides and cisplatin
what will you see on urine microscopy in acute tubular necrosis?
- ✔✔✔ correct answer > granular brown muddy casts
glomerular hematuria vs non glomerular hematuria, what will
you see on urinalysis? - ✔✔✔ correct answer > Glomerular hematuria
- blood & protein
- RBC casts, dysmorphic RBC's
Non-glomerular hematuria
- blood but no protein
- normal appearing RBC's
, Page 4 of 44
in chronic renal disease, why is there decreased calcium and
increased phosphorus? - ✔✔✔ correct answer > GFR decreases
causing an increase in phosphorous
Vitamin D production decreases, which causes a decrease in the
absorption of calcium as well as the phosphorous binding up the
calcium and decreasing serum calcium
explain the pathophysiology of renal osteodystrophy? - ✔✔✔ correct
answer > chronic kidney disease causes a decrease in the serum
calcium and an increase in the serum phosphorous.
this causes an increase in PTH synthesis (secondary
hyperparathyroidism)
This leads to increased bone resporption (osteitis fibrosa cystica)
which leads to bone pain
What happens to the parathyroid glands in secondary
hyperparathyroidism? - ✔✔✔ correct answer > hyperplasia
what happens to the parathyroid glands if secondary
hyperparathyroidism goes untreated? - ✔✔✔ correct answer >
UWORLD STEP 2 SELF ASSESMENT 1 EXAM
NEWEST 2026 ACTUAL EXAM QUESTIONS AND
CORRECT DETAILED ANSWERS (VERIFIED
ANSWERS) ALL ANSWERED {190 Q & A}
ALREADY GRADED A+ | BRAND NEW! | 100%
GUARANTEED PASS
What is the treatment of primary hyperaldosteronism if teh
cause is bilateral adrenal hyperplasia? - ✔✔✔ correct answer >
aldonsterone antagonist
- spironolactone
- epleronone
If someone is suspicious for epithelial ovarian carcinoma and you
see pleural effusions and nodularity of the rectovaginal septum,
what are you thinking? - ✔✔✔ correct answer > Metastatic spread
in hypercalcemia of malignancy (small cell carcinoma) the
calcium levels can rise very fast, what are the consequences of
this compared to primary hyperparathyroidism? - ✔✔✔ correct
answer > Hypercalcemia of malignancy causes a very rapid rise in
calcium to a very high level (>12). This causes neurologic
symptoms such as lethargy, coma, delerium, and confusion
,Page 2 of 44
Hypercalcemia of primary hyperparathyroidism causes a rise in
calcium but not >12 usually and does not cause as pronounced
neurological symptoms
what are some early and late complications of Roux-en-Y gastric
bypass surgery? - ✔✔✔ correct answer > Early
- Anastomotic leak (sepsis)
- Bowel ischemia (diffuse abdominal pain)
LAte
- Anastomotic stricture (dysphagia, bowel obstruction
- CHOLECYSTITIS
- Dumping syndrome (Diarrhea,vomiting, crampy abdominal pain,
flushing, palpitations)
why do people who under go Roux-en-Y gastric bypass surgery
get gallstones and cholecystitis? - ✔✔✔ correct answer > because
they lose a lot of weight fast. which causes the gallstones
why do people who under go roux-en-Y gastric bypass surgery
get dumping syndrome? - ✔✔✔ correct answer > because of rapid
gastric emptying
,Page 3 of 44
Which drugs can cause acute interstitial nephritis? - ✔✔✔ correct
answer > NSAIDS, PPI,
What will a urine microscopy show in acute interstitial nephritis?
- ✔✔✔ correct answer > eosinophils
What drugs cause acute tubular necrosis? - ✔✔✔ correct answer >
Aminoglycosides and cisplatin
what will you see on urine microscopy in acute tubular necrosis?
- ✔✔✔ correct answer > granular brown muddy casts
glomerular hematuria vs non glomerular hematuria, what will
you see on urinalysis? - ✔✔✔ correct answer > Glomerular hematuria
- blood & protein
- RBC casts, dysmorphic RBC's
Non-glomerular hematuria
- blood but no protein
- normal appearing RBC's
, Page 4 of 44
in chronic renal disease, why is there decreased calcium and
increased phosphorus? - ✔✔✔ correct answer > GFR decreases
causing an increase in phosphorous
Vitamin D production decreases, which causes a decrease in the
absorption of calcium as well as the phosphorous binding up the
calcium and decreasing serum calcium
explain the pathophysiology of renal osteodystrophy? - ✔✔✔ correct
answer > chronic kidney disease causes a decrease in the serum
calcium and an increase in the serum phosphorous.
this causes an increase in PTH synthesis (secondary
hyperparathyroidism)
This leads to increased bone resporption (osteitis fibrosa cystica)
which leads to bone pain
What happens to the parathyroid glands in secondary
hyperparathyroidism? - ✔✔✔ correct answer > hyperplasia
what happens to the parathyroid glands if secondary
hyperparathyroidism goes untreated? - ✔✔✔ correct answer >
