2-3 - answerHow many symptoms for mild substance disorder?
4-5 - answerHow many symptoms for moderate substance disorder?
6+ - answerHow many symptoms for severe substance disorder?
Severe alcohol intoxication - answerWhat diagnosis do they have? Nervous system
depression (sleepiness, coma, lethargy, and decreased response to pain).
Withdrawal accompanied by pain
Digestive problems that include vomiting, bleeding, and dehydration
Slow or absent breathing
Grand mal seizures
Delirium tremens (DTs)
Disturbances of vision, mental confusion, and muscular incoordination
Disinterested behavior and loss of memory
Can cause alcoholic ketoacidosis, alcoholic hypoglycemia, fluid and electrolyte
imbalance, Wernicke's encephalopathy, acute effects on heart, acute GI effects, acute
alcoholic myopathy, trauma, and associated other substance poisoning.
Misuse - answerPatient is prescribed Norco to take one pill every four hours but he
takes 10 pills every hour. Patient is displaying?
guidelines - answerThe use of prescription drugs in a manner other than directed by
medical _____________ is misuse
Abuse - answerA maladaptive pattern of substance use leading to clinically significant
impairment or distress
Abuse of Medication - answerDysfunction; Using the drug beyond the way it's
prescribed for
1, 12 - answerAbuse is manifested by: ____ or more of the following occurring over a
____ month period:
Recurrent substance use resulting in a failure to fulfill major obligations at work, school,
or home
Recurrent substance use in situations in which it is physically hazardous
Recurrent substance related legal problems
Continued substance use despite persistent or recurrent social or interpersonal
problems.
,failure to fulfill, hazardous - answerManifested by one or more of the following occurring
over a 12 month period:
-Recurrent substance use resulting in a _________ ______ __________ major
obligations at work, school, or home
-Recurrent substance use in situations in which it is physically ___________.
-Recurrent substance related legal problems
-Continued substance use despite persistent or recurrent social or interpersonal
problems.
craving, withdrawal - answer3 major features of abuse: compulsive intake,
_____________, and ______________.
What is cross-tolerance? - answerThe ability of one drug to be substituted for another
drug that produces the same physiological and psychological effects
Which substances can exhibit cross-tolerance? - answerValium, barbiturates, alcohol
since they act on similar receptors of the brain
Detoxification - answerAbrupt cessation of alcohol intake for an individual that has had
dependence.
Often coupled with a substitution of drugs that have a similar effect.
If stop opioids, take buprenorphine.
If stop taking alcohol, take campral.
It's taking the toxins out of the body.
Many facilities have protocols for this
acute - answerDetox helps manage _________ withdrawal symptoms
Consequences - answerIn dependence, The dosage and frequency not the
issue..._________________ are the issue
Dependence - answerAdaptation and deterioration are hallmarks
Campral - answerArtificial alcohol drug
immediately - answerAdminister Campral ______________ following acute withdrawal
reduces - answerCampral _______________ glutamate and increases GABA
renal - answerCampral is contraindicated in ____________ impairment
abdominal cramping - answerCommon side effect of Campral
opioid partial agonist - answerBuprenorphine (Subutex) MOA:
, Subutex - answerDon't really want to use ______________ because you can get high
off of it. Sells on the street for 80 dollars per pill.
Can also give it IV.
pregnant - answerYou should only prescribe buprenorphine (Subutex) if the patient is
____________ or they have an allergy to Suboxone.
Suboxone - answer_______________ is a combination of Buprenorphine and
naltrexone
naltrexone - answerIn Suboxone, If you take too much Buprenorphone, the
_________________ will counteract the effects and helps block out/stop the opiate's
effect if they take too much.
7, 14 - answerWhen to start Wellbutrin on someone who smokes? _____ to ____ days
before they stop smoking.
150 - answerWellbutrin: In the first 6 days, one _________mg tablet is to be taken each
morning.
From the 7th day onwards, 2 tablets are to be taken daily, 1 first thing in the morning
and 1 in the afternoon (at least 8 hours after the first)
7, 9 weeks - answertreatment of wellbutrin for nicotine us should last around ____ to
_____ __________.
seizures - answerWellbutrin is contraindicated if pt has
Librium - answerUse during withdrawal of alcohol to prevent seizure. Has long half life.
opioid withdrawal - answerClonidine (Catapres): Can give this when going through
___________ ____________ symptoms.
locus, abate - answerClonidine is helpful because it decreases sympathetic activity from
the _________ coeruleus and is thought to _________ opioid withdrawal symptoms.
Clonidine decreases BP, heart rate, sweating, palpitations.
OH - answerSE of Clonidine
Rebound tachycardia and hypertension - answerIf stop clonidine abruptly it can cause a
rebound effect:
alcohol abstinence - answerDisulfiram (Antabuse): FDA approved for
acetaldehyde - answerAntabuse: Accumulation of ______________ in the blood
produces unpleasant symptoms