Nurs 498 Questions Midterm 1
questions with complete solutions
2025/2026
Which potential problem is of most concern for a patient receiving immunosuppressant drugs?
a. Increased susceptibility to infections
b. Orthostatic hypotension
c. Neurotoxicity
d. Confusion - CORRECT ANSWER ✔✔a. Increased susceptibility to infections
Rationale: Neurotoxicity and confusion may be a problem with some immunosuppressants but
a heightened susceptibility to opportunistic infections is a major risk factor for
immunosuppressed patients.
A patient with active HIV has been taking zidovudine (Retrovir®). Which potential adverse effect
may limit the length of time this medication can be taken?
a. hepatomegaly
b. Bone marrow suppression
c. Lactic acidosis
d. fatigue - CORRECT ANSWER ✔✔b. Bone marrow suppression
The nurse working in an HIV testing and treatment clinic plans teaching about antiretroviral
therapy for which of the following clients?
, a. A client with persistent generalized lymphadenopathy who was exposed to HIV 2 years
previously
b. A client who tested positive for HIV 3 years ago and has developed tuberculosis
c. A client who was infected with HIV 10 years ago and has a CD4+ T-cell count of 650/μL
d. A male health care worker who is HIV negative but has unprotected sex with men - CORRECT
ANSWER ✔✔b. A client who tested positive for HIV 3 years ago and has developed tuberculosis
Before administering methitrexate to a patient, what is most important for the nurse to assess?
a. Latent tuberculosis
b. Allergy to eggs
c. Congestive heart failure
d. hypothyroidism - CORRECT ANSWER ✔✔a. Latent tuberculosis
A female patient has started azathioprine (Imuran®) therapy in preparation for her kidney
transplant surgery. Which expected adverse effect of azathioprine therapy should the nurse tell
the patient about?
a. Fluid retention
b. Leukopenia
c. Diarrhea
d. Tremors - CORRECT ANSWER ✔✔b. Leukopenia
Rationale: Leukopenia is an expected adverse effect of azathioprine therapy.
Which statement is true in regard to cyclosporine?
questions with complete solutions
2025/2026
Which potential problem is of most concern for a patient receiving immunosuppressant drugs?
a. Increased susceptibility to infections
b. Orthostatic hypotension
c. Neurotoxicity
d. Confusion - CORRECT ANSWER ✔✔a. Increased susceptibility to infections
Rationale: Neurotoxicity and confusion may be a problem with some immunosuppressants but
a heightened susceptibility to opportunistic infections is a major risk factor for
immunosuppressed patients.
A patient with active HIV has been taking zidovudine (Retrovir®). Which potential adverse effect
may limit the length of time this medication can be taken?
a. hepatomegaly
b. Bone marrow suppression
c. Lactic acidosis
d. fatigue - CORRECT ANSWER ✔✔b. Bone marrow suppression
The nurse working in an HIV testing and treatment clinic plans teaching about antiretroviral
therapy for which of the following clients?
, a. A client with persistent generalized lymphadenopathy who was exposed to HIV 2 years
previously
b. A client who tested positive for HIV 3 years ago and has developed tuberculosis
c. A client who was infected with HIV 10 years ago and has a CD4+ T-cell count of 650/μL
d. A male health care worker who is HIV negative but has unprotected sex with men - CORRECT
ANSWER ✔✔b. A client who tested positive for HIV 3 years ago and has developed tuberculosis
Before administering methitrexate to a patient, what is most important for the nurse to assess?
a. Latent tuberculosis
b. Allergy to eggs
c. Congestive heart failure
d. hypothyroidism - CORRECT ANSWER ✔✔a. Latent tuberculosis
A female patient has started azathioprine (Imuran®) therapy in preparation for her kidney
transplant surgery. Which expected adverse effect of azathioprine therapy should the nurse tell
the patient about?
a. Fluid retention
b. Leukopenia
c. Diarrhea
d. Tremors - CORRECT ANSWER ✔✔b. Leukopenia
Rationale: Leukopenia is an expected adverse effect of azathioprine therapy.
Which statement is true in regard to cyclosporine?
