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Test Bank for Porth's Essentials of Pathophysiology 5th Edition by Tommie L Norris

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This test bank accompanies Porth's Essentials of Pathophysiology, 5th Edition by Tommie L. Norris. It provides comprehensive coverage of core pathophysiology concepts with a complete answers key to support exam preparation and self-study. The material covers the pathophysiology of major body systems, disease mechanisms, clinical manifestations, and progression of illnesses. Ideal for nursing students, pre-nursing programs, ADN and BSN courses, and healthcare professionals seeking to strengthen foundational knowledge in disease processes. This resource is perfect for practice exams, quizzes, assignments, and self-study, helping students master pathophysiologic principles and apply them in clinical practice.

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Test Bank for
Porth's Essentials of Pathophysiology 5th edition
by Tommie L Norris

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1. Chapter 1

Although the basic structure of the cell plasma membrane is formed by a lipid bilayer, most of
the specific membrane functions are carried out by:

A) Bound and transmembrane proteins

B) Complex, long carbohydrate chains

C) Surface antigens and hormone receptors

D) A gating system of selective ion channels

Ans: A

Feedback:

The functions of plasma membrane depend on the presence of proteins that are bound in the lipid
bilayer and some that have the ability to pass freely into and out of the cell.

Carbohydrate chains form a cell coat that surrounds the membrane and that contain surface
antigens and surface hormone receptors. Some ion channels are gated and open only when the
membrane potential changes significantly.

2. Which describes the function of the nucleus?

A) It is basically the site of protein synthesis in the body.

B) It contains the genetic code for the individual.

C) It is the transformer of cellular energy.

D) It initiates the process of aerobic metabolism.

Ans: B

Feedback:

The nucleus contains DNA, which contains the genetic code that contains the information that
controls cells. Ribosomes synthesize protein. Mitochondria transform organic compounds into
cellular energy. Mitochondria require oxygen for aerobic metabolism, using hydrogen and
carbon combined with oxygen molecules to form carbon dioxide and water as energy is released.

3. Which of the following aspects of the function of the nucleus is performed by ribosomal
RNA (rRNA)?

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A) Copying and carrying DNA instructions for protein synthesis

B) Carrying amino acids to the site of protein synthesis

C) Providing the site where protein synthesis occurs

D) Regulating and controlling protein synthesis

Ans: C

Feedback:

There are three types of ribonucleic acid (messenger RNA, ribosomal RNA, and transfer RNA)
that move to the cytoplasm and carry out the actual synthesis of proteins.

Messenger RNA (mRNA) copies and carries the DNA instructions for protein synthesis to the
cytoplasm; ribosomal RNA (rRNA) is the site of protein synthesis; and transfer RNA (tRNA)
transports amino acids to the site of protein synthesis for incorporation into the protein being
synthesized.

4. Which accurately explains the functions of the organelles lysosomes? They:

A) Are sacs filled with enzymes that breakdown and remove foreign substances and worn-
out cell parts

B) Function in association with the endoplasmic reticulum to modify protein end products
and package them into secretory granules or vesicles

C) Are small particles of nucleoproteins that are involved in the synthesis of proteins that
remain in the cell as cytoplasmic structural or functional elements

D) Are a dynamic system of interconnected membranous tubes that functions as a tubular
communication system for transporting various substances from one part of the cell to another

Ans: A

Feedback:

Lysosomes are sacs that are filled with hydrolytic enzymes that aid in the processing and
removal of unwanted substances within the cytoplasm. The Golgi apparatus functions in
association with the endoplasmic reticulum to modify and package substances in preparation for
secretion, whereas ribosomes are small particles of nucleoproteins that are involved in the
synthesis of proteins. The ER is a tubular communication system for transporting various
substances from one part of the cell to another.

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5. Impairment in the function of peroxisomes would result in:

A) Inadequate sites for protein synthesis

B) An inability to transport cellular products across the cell membrane

C) Insufficient energy production within a cell

D) Accumulation of free radicals in the cytoplasm

Ans: D

Feedback:

Peroxisomes function in the control of free radicals; unless degraded, these highly unstable
chemical compounds damage other cytoplasmic molecules. Peroxisomes do not directly
contribute to energy production, protein synthesis, or transport of cellular secretions.

6. Although energy is not made in mitochondria, they are known as the “power plants” of
the cell because they:

A) Contain RNA for protein synthesis

B) Utilize glycolysis for oxidative energy

C) Extract energy from organic compounds

D) Store calcium bonds for muscle contractions

Ans: C

Feedback:

Mitochondria contain the enzymes needed for transforming organic compounds into energy that
is easily accessible to the cell. Mitochondria contain their own DNA. Glycolysis is anaerobic
metabolism and unrelated to oxidative energy. Mitochondria store phosphate bonds (such as in
ATP) to power cellular functions.

7. Semen analysis indicates that the client's sperm have decreased motility. Which of the
following cellular components may be defective within the client's sperm?

A) Ribosomes

B) Microtubules

C) Mitochondria

D) Microfilaments

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