1
TEST BANK FOR GENETICS FROM
GENES TO GENOMES 6TH EDITION
BY HARTWELL
GeneticsFromGenesToGenomes6thEdition H
j j j j j j j
artwell Test Bank j j
Hartwell
Chapterj1j Genetics:jThejStudyjofjBiologicaljInformation
1) HowjdoesjDNAjstructurejrelatejtojitsjfunction?
- ThejorderjofjnucleotidesjinjajDNAjstrandjspecifiesjthejorderjofjaminojacidsjinjaIpr
otein.
2) WhatjisjajdifferencejbetweenjthejstructurejofjDNAjandjproteins?
- DNAjisjcomposedjofjnucleotidesjandjproteinsjarejcomposedjofjaminojacids.
3) Ajgenomejcanjbejbestjdescribedjas
- thejDNAjinjalljchromosomesjinjajcell.
4) WhatjisjthejdifferencejbetweenjthejfunctionjofjDNAjandjthejfunctionjofjproteins?
- DNAjstoresjgeneticjinformationjandjproteinsjperformjmostjcellularjfunctions.
5) Whichjstatementjsupportsjthejtheoryjthatjalljorganismsjarejrelated?
- Thejgeneticjcodejisjalmostjuniversal.
6) Newjgenesjarejthoughtjtojarisejbyjwhichjmechanism?
- Genejduplicationjfollowedjbyjdivergencejduejtojmutation.
7) Whatjisjthejmostjlikelyjwayjajmutationjinjonejgenejcanjconvertjonejbodyjpartjto
TEST BANK FOR GENETICS FROM GENES TO GENOMES 6TH EDITION BY HARTWELL
, 2
another?
- Thejmutatedjgenejencodesjajproteinjthatjaffectsjthejexpressionjofjmanyjother
genes.
8) Ajrecentjtechnicaljadvancementjthatjhasjacceleratedjthejstudyjofjgenomesjisjthejabi
lityto
- sequencejlargejcomplexjgenomesjrapidlyjandjinexpensively.
9) Whatjisjthejdifferencejbetweenjgeneticjdissectionjandjgenomejsequencing?
- Geneticjdissectionjrevealsjinformationjaboutjonejgenejatjajtimejandjgeno
mesequencingjrevealsjinformationjaboutjalljthejgenesjinjajgenomejatjonce.
10) Currently,jwhatjinformationjcanjbejobtainedjfromjsequencingjanjindividual'sjgenome?
- Informationjaboutjgenejvariantsjthatjpredisposejajpersonjtojajdisease,jsuchjasI
cancer.
11) Whichjisjnotjajpotentialjproblemjofjallowingjthejgenomicjsequencesjofjindividualsjto
becomejwidelyjavailable?
- Advancesjleadingjtojhealthierjlivesjforjsomejpeople.
TEST BANK FOR GENETICS FROM GENES TO GENOMES 6TH EDITION BY HARTWELL
, 3
12) OnejstrandjofjDNAjhasjthejsequencej5′jGGTCTAj3′.jWhatjisjthejsequencejofjthejotherstra
nd?
- 5′jTAGACCj3′
13) WhichjstatementjisjtruejaboutjthejstructurejofjDNA?
- ThejtwojstrandsjofjajDNAjmoleculejarejheldjtogetherjbyjbasejpairing.
14) Thejsizejofjthejmousej(M.jmusculus)jgenomejisj2700jmegabasesj(Mb)j andj itj containsjab
outj25,000jgenesjarrangedjonj40jchromosomes.jIfjthejgenesjarejevenlyjdistributedjonjchro
mosomesjinjthejmouse,jwhatjisjthejaveragejnumberjofjgenesjperjchromosome?
-j625
15) Whichjstatementjaboutjthejstructurejofjproteinsjisjfalse?
- Mostjproteinsjconsistjofjtwojaminojacidjpolymersjattachedjtogetherjbyjhydrogenjbo
nding.
16) WhichjisjajstructuraljfeaturejsharedjbyjDNA,jRNA,jandjproteins?
- Thejorderjofjmonomersjisjimportantjforjfunction.
17) AjsegmentjofjajproteinjhasjthejaminojacidjsequencejSer—Gly—
Leu.jIsjitjpossiblejtoinferjthejsequencejofjthejRNAjthatjencodesjthisjaminojacidjsequence?
No;jmorejthanjonejtypejofjRNAj(morejthanjonejbasejsequence)jcouldjencodejthisjaminoacidjse
quence.
TEST BANK FOR GENETICS FROM GENES TO GENOMES 6TH EDITION BY HARTWELL
, 4
18) AjsequencejofjbasesjinjthejmiddlejofjanjRNAjusedjtojencodejajpolypeptidejhasjthejsequen
cejUUA—AUG—
CGU.jIsjitjpossiblejtojinferjthejsequencejofjthejaminojacidsjencodedjbyjthisjRNA?
- Yes,jthejsequencejisjLeu—Met—Arg.
19) Mutationjofjajmousejgenejresultsjinjmicejthatjlackjheartjmuscle.jWhatjcharacteristicjwo
uldjyoujexpectjtojfindjinjajhumanjgenejthatjhasjajcommonjoriginjwithjthisjmousejgene?
- Thejhumanjandjmousejgenesjwilljspecifyjproteinsjwithjsimilarjaminojac
idsequences.
20) Ajmousejgenejwasjidentifiedjandjdeterminedjtojbejrequiredjforjformationjofjheartjmu
scle.jAjgenejwithjajsimilarjsequencejwasjidentifiedjinjthejhumanjgenome.jWhatjexperime
ntjcouldjscientistsjdojtojdeterminejifjthejmousejandjhumanjgenesjhavejsimilarfunctions?
- Thejscientistjcouldjplacejthejnormaljhumanjgenejintojmutantjmicejtojseejifjhe
artmusclejformsjinjthejmouse.
TEST BANK FOR GENETICS FROM GENES TO GENOMES 6TH EDITION BY HARTWELL
TEST BANK FOR GENETICS FROM
GENES TO GENOMES 6TH EDITION
BY HARTWELL
GeneticsFromGenesToGenomes6thEdition H
j j j j j j j
artwell Test Bank j j
Hartwell
Chapterj1j Genetics:jThejStudyjofjBiologicaljInformation
1) HowjdoesjDNAjstructurejrelatejtojitsjfunction?
- ThejorderjofjnucleotidesjinjajDNAjstrandjspecifiesjthejorderjofjaminojacidsjinjaIpr
otein.
2) WhatjisjajdifferencejbetweenjthejstructurejofjDNAjandjproteins?
- DNAjisjcomposedjofjnucleotidesjandjproteinsjarejcomposedjofjaminojacids.
3) Ajgenomejcanjbejbestjdescribedjas
- thejDNAjinjalljchromosomesjinjajcell.
4) WhatjisjthejdifferencejbetweenjthejfunctionjofjDNAjandjthejfunctionjofjproteins?
- DNAjstoresjgeneticjinformationjandjproteinsjperformjmostjcellularjfunctions.
5) Whichjstatementjsupportsjthejtheoryjthatjalljorganismsjarejrelated?
- Thejgeneticjcodejisjalmostjuniversal.
6) Newjgenesjarejthoughtjtojarisejbyjwhichjmechanism?
- Genejduplicationjfollowedjbyjdivergencejduejtojmutation.
7) Whatjisjthejmostjlikelyjwayjajmutationjinjonejgenejcanjconvertjonejbodyjpartjto
TEST BANK FOR GENETICS FROM GENES TO GENOMES 6TH EDITION BY HARTWELL
, 2
another?
- Thejmutatedjgenejencodesjajproteinjthatjaffectsjthejexpressionjofjmanyjother
genes.
8) Ajrecentjtechnicaljadvancementjthatjhasjacceleratedjthejstudyjofjgenomesjisjthejabi
lityto
- sequencejlargejcomplexjgenomesjrapidlyjandjinexpensively.
9) Whatjisjthejdifferencejbetweenjgeneticjdissectionjandjgenomejsequencing?
- Geneticjdissectionjrevealsjinformationjaboutjonejgenejatjajtimejandjgeno
mesequencingjrevealsjinformationjaboutjalljthejgenesjinjajgenomejatjonce.
10) Currently,jwhatjinformationjcanjbejobtainedjfromjsequencingjanjindividual'sjgenome?
- Informationjaboutjgenejvariantsjthatjpredisposejajpersonjtojajdisease,jsuchjasI
cancer.
11) Whichjisjnotjajpotentialjproblemjofjallowingjthejgenomicjsequencesjofjindividualsjto
becomejwidelyjavailable?
- Advancesjleadingjtojhealthierjlivesjforjsomejpeople.
TEST BANK FOR GENETICS FROM GENES TO GENOMES 6TH EDITION BY HARTWELL
, 3
12) OnejstrandjofjDNAjhasjthejsequencej5′jGGTCTAj3′.jWhatjisjthejsequencejofjthejotherstra
nd?
- 5′jTAGACCj3′
13) WhichjstatementjisjtruejaboutjthejstructurejofjDNA?
- ThejtwojstrandsjofjajDNAjmoleculejarejheldjtogetherjbyjbasejpairing.
14) Thejsizejofjthejmousej(M.jmusculus)jgenomejisj2700jmegabasesj(Mb)j andj itj containsjab
outj25,000jgenesjarrangedjonj40jchromosomes.jIfjthejgenesjarejevenlyjdistributedjonjchro
mosomesjinjthejmouse,jwhatjisjthejaveragejnumberjofjgenesjperjchromosome?
-j625
15) Whichjstatementjaboutjthejstructurejofjproteinsjisjfalse?
- Mostjproteinsjconsistjofjtwojaminojacidjpolymersjattachedjtogetherjbyjhydrogenjbo
nding.
16) WhichjisjajstructuraljfeaturejsharedjbyjDNA,jRNA,jandjproteins?
- Thejorderjofjmonomersjisjimportantjforjfunction.
17) AjsegmentjofjajproteinjhasjthejaminojacidjsequencejSer—Gly—
Leu.jIsjitjpossiblejtoinferjthejsequencejofjthejRNAjthatjencodesjthisjaminojacidjsequence?
No;jmorejthanjonejtypejofjRNAj(morejthanjonejbasejsequence)jcouldjencodejthisjaminoacidjse
quence.
TEST BANK FOR GENETICS FROM GENES TO GENOMES 6TH EDITION BY HARTWELL
, 4
18) AjsequencejofjbasesjinjthejmiddlejofjanjRNAjusedjtojencodejajpolypeptidejhasjthejsequen
cejUUA—AUG—
CGU.jIsjitjpossiblejtojinferjthejsequencejofjthejaminojacidsjencodedjbyjthisjRNA?
- Yes,jthejsequencejisjLeu—Met—Arg.
19) Mutationjofjajmousejgenejresultsjinjmicejthatjlackjheartjmuscle.jWhatjcharacteristicjwo
uldjyoujexpectjtojfindjinjajhumanjgenejthatjhasjajcommonjoriginjwithjthisjmousejgene?
- Thejhumanjandjmousejgenesjwilljspecifyjproteinsjwithjsimilarjaminojac
idsequences.
20) Ajmousejgenejwasjidentifiedjandjdeterminedjtojbejrequiredjforjformationjofjheartjmu
scle.jAjgenejwithjajsimilarjsequencejwasjidentifiedjinjthejhumanjgenome.jWhatjexperime
ntjcouldjscientistsjdojtojdeterminejifjthejmousejandjhumanjgenesjhavejsimilarfunctions?
- Thejscientistjcouldjplacejthejnormaljhumanjgenejintojmutantjmicejtojseejifjhe
artmusclejformsjinjthejmouse.
TEST BANK FOR GENETICS FROM GENES TO GENOMES 6TH EDITION BY HARTWELL
