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NUR 376 Medical-Surgical Nursing | Exam 1 (2026) | 140 Questions with Answers | ABGs, Electrolytes, COPD, TB, Acid-Base

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This expert-verified resource for NUR 376 – Medical-Surgical Nursing includes 140 comprehensive practice questions and answers tailored for Exam 1 of the 2026 academic year. Structured in a high-yield Q&A format, it offers a deep and clinically relevant review of essential topics in adult health nursing. Major areas covered include arterial blood gases (ABGs) and acid-base imbalances (metabolic/respiratory acidosis and alkalosis), with causes, symptoms, and compensatory mechanisms. It provides detailed normal ranges and interpretation strategies, including the ROME method. The document thoroughly reviews fluid and electrolyte imbalances, including sodium, potassium, calcium, magnesium, phosphorus, and chloride. Each section includes clinical manifestations, priority nursing interventions, and treatments—such as when to use IV fluids, dietary changes, or pharmacologic agents. Also featured are respiratory conditions and interventions, including pneumonia, COPD, asthma, tuberculosis (TB), atelectasis, and related nursing management strategies (e.g., oxygen therapy, tracheostomy care, suctioning, and chest physiotherapy). Key pharmacological therapies for asthma and COPD are included, such as bronchodilators, corticosteroids, mucolytics, and emergency respiratory interventions. Who is this document for? BSN (Bachelor of Science in Nursing) students ADN (Associate Degree in Nursing) students Students enrolled in Medical-Surgical, Adult Health, or Respiratory Nursing courses NCLEX-RN candidates focusing on acute care and clinical readiness With a focus on lab interpretation, clinical decision-making, and nursing priorities, this study guide is an essential tool for excelling in exams and clinical performance in med-surg nursing. Keywords: medical surgical nursing, NUR 376, ABG interpretation, acid base imbalance, electrolytes, respiratory nursing, COPD, asthma, pneumonia, tuberculosis, oxygen therapy, NCLEX prep, nursing pharmacology, tracheostomy care, fluid and electrolyte management

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NUR 376 Exam 1 2026 Expert
Verified | Ace the Test



Arterial blood gas (ABG) - 🧠 ANSWER ✔✔blood test from an artery instead

of the vein to see o2 and co2 levels


normal pH - 🧠 ANSWER ✔✔7.35 - 7.45


normal PaCO2 - 🧠 ANSWER ✔✔35-45 mmHG


Normal HCO3 (bicarbonate) - 🧠 ANSWER ✔✔22-26 mEq/L


normal PaO2 - 🧠 ANSWER ✔✔80-100 mmHg


normal O2 stat - 🧠 ANSWER ✔✔>94%


Metabolic Acidosis - 🧠 ANSWER ✔✔low pH <7.35

,low bicarb <22 mEq/L




commonly due to kidney injury


Metabolic Acidosis Causes (8) - 🧠 ANSWER ✔✔- DKA (diabetes)


- Hyperkalemia

- Starvation

- Shock

- Renal Failure

- Aspirin overdose

- Tricyclic antidepressant overdose

- Diarrhea (acidosis out the ass)


Metabolic Acidosis s/s (6) - 🧠 ANSWER ✔✔- Headache


- Decreased BP, Muscle tone, reflexes

- Hyperkalemia

- Muscle Twitching

- Warm skin

, - Kussmaul Respirations


Kussmaul respirations - 🧠 ANSWER ✔✔very deep and rapid respirations


Metabolic Alkalosis - 🧠 ANSWER ✔✔High pH >7.45


High bicarb > 26 mEq/L




commonly due to medication or long term diuretic use


Metabolic Alkalosis Cause (6) - 🧠 ANSWER ✔✔- Large blood transfusions


- Prolonged vomiting (bulimia too)

- Significant NG output

- Diuretic overuse

- Hypokalemia

- Mineralcorticoid excess


Metabolic Alkalosis s/s - 🧠 ANSWER ✔✔- restlessness w/ lethargy


- dysrhythmias

- hypoventilation

- confusion

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