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NUR 377 Medical-Surgical & Critical Care Nursing | Exam 3 (2026) | 115 Questions with Answers | DKA, HHS, Renal Failure, Endocrine Crisis, Neuro Trauma

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This expert-verified study resource for NUR 377 – Medical-Surgical and Critical Care Nursing contains 115 high-yield questions with answers, tailored to Exam 3 of the 2026 curriculum. It provides comprehensive coverage of endocrine, renal, and neurological disorders, using a clinically focused Q&A format ideal for NCLEX-style preparation. Key topics include: Diabetic Ketoacidosis (DKA) & HHS: Pathophysiology, symptoms (Kussmaul respirations, fruity breath, altered mental status), insulin therapy protocols (IV regular insulin, glucose monitoring, potassium replacement), and distinguishing features between DKA (acidic, T1DM) and HHS (no acidosis, T2DM). Hypoglycemia & Hyperglycemia: Early and late signs, treatment algorithms (15/15/15 rule, glucagon, D50), and nursing interventions for prevention and management across mild to severe presentations. Endocrine Crises: Diabetes Insipidus (DI): Types (central, nephrogenic), lab values, and drug management with desmopressin or thiazides. SIADH: Fluid retention, hyponatremia, and emergency use of hypertonic saline. Myxedema Coma: Hypothyroid crisis symptoms and treatment (levothyroxine, steroids, airway management). Thyroid Storm: Hyperthyroid emergency with high fever, tachycardia, and management (PTU, beta blockers, iodine, avoid NSAIDs). Addison's Disease & Cushing’s Syndrome: Hormonal imbalances, skin changes, lab monitoring, and pharmacologic management. Renal Failure (AKI & CKD): Chronic Kidney Disease (CKD): Staging (GFR-based), s/s (uremic frost, electrolyte imbalance), dietary restrictions, anemia, and dialysis timing. Acute Kidney Injury (AKI): Prerenal, intrarenal, postrenal causes, lab trends (BUN, creatinine, electrolytes), and fluid management across the oliguric, diuretic, and recovery phases. Dialysis (HD & PD): Hemodialysis vs. peritoneal dialysis mechanisms, access management (fistula care, bruit/thrill), complications (disequilibrium syndrome, peritonitis), and dietary needs. Electrolyte Emergencies & Interventions: Hyperkalemia: “C BIG K Drop” mnemonic – Calcium gluconate, Beta agonists, Insulin + Glucose, Kayexalate, Dialysis. Sodium/osmolality issues in SIADH/DI, and fluid shifts in renal/endocrine failure. Neuro Trauma & ICP Management: Increased ICP: Causes, symptoms (Cushing's Triad), management with mannitol/hypertonic saline, and nursing care (HOB elevation, neuro checks). Basilar Skull Fractures & CSF Leaks: Assessment signs (Battle’s sign, raccoon eyes), CSF testing, and precautions. Seizures & Status Epilepticus: Safety measures, pharmacologic interventions (benzodiazepines, phenytoin, fosphenytoin), and postictal care. Who is this document for? BSN and ADN nursing students Students enrolled in Advanced Medical-Surgical, Critical Care, or Endocrine/Neuro/Renal-focused nursing modules NCLEX-RN candidates preparing for high-stakes patient care and emergency nursing This resource supports deep clinical reasoning, rapid prioritization, and integrated systems thinking across high-acuity care topics—making it an essential tool for exam readiness and future practice. Keywords: NUR 377, medical surgical nursing, critical care nursing, DKA, HHS, diabetes insipidus, SIADH, myxedema coma, thyroid storm, Addison’s disease, Cushing’s syndrome, AKI, CKD, dialysis, hyperkalemia, C BIG K Drop, increased ICP, CSF leak, seizures, NCLEX prep

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NUR 377 Exam 3 2026 Expert
Verified | Ace the Test



Diabetic Ketoacidosis - 🧠 ANSWER ✔✔Body doesn't have insulin to allow

blood sugar into cells for use of energy, liver breaks down fats for energy

creating lots of ketones (common in T1DM)




- acidosis (pH < 7.35)

- hyperglycemia

- dehydration

- electrolyte loss

,Osmotic Diuresis - 🧠 ANSWER ✔✔sugar levels exceed the ability of

kidneys to reabsorb, glucose overflows into the urine taking water and

electrolytes with it (dehydration and electrolyte problems ensue)


DKA s/s - 🧠 ANSWER ✔✔- Dry body (dehydrated)


- high sugar (250-500 mg/dL)

- Ketones (fruity breath)

- Kussmaul respirations

- Abdominal pain

- Metabolic acidosis


DKA Causes - 🧠 ANSWER ✔✔Sepsis/infection


Sickness (vomiting/diarrhea)

Stress (surgery)

Skiping insulin


DKA tx - 🧠 ANSWER ✔✔1. REHYDRATE -> NS initially is the priority


2. Killing sugar slowly, so insulin bolus and then drip ALWAYS REGULAR

insulin, BG checks q1h

,3. Once BG <250 or ketones resolved, subq insulin and dextrose to the IV,

BG checks q2h

4. Add potassium to IV fluids (or by self) during IV insulin (if K+ is on lower

end of normal or below)


Potassium and insulin - 🧠 ANSWER ✔✔insulin pushes potassium into the

cells -> lowers serum potassium


Hyperglycemic Hyperosmolar Syndrome (HHS) - 🧠 ANSWER ✔✔a

metabolic disorder of T2DM resulting from a relative insulin deficiency

caused by an illness that raises the demand for insulin, BG > 600 mg/dL


HHS s/s - 🧠 ANSWER ✔✔- mental status changes (DKA doesn't have)


- PROFOUND dehydration

- normal pH (no acidosis)

- no ketones

- shallow breaths

- slow onset

- greater osmolality


HHS tx - 🧠 ANSWER ✔✔- Hydration first

COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
PRIVACY STATEMENT. ALL RIGHTS RESERVED

, - Stabilize blood sugar with insulin IV and then convert to subq when <200

- Reassess hydration and BG q1h

- decreased GFR so NO K+ replacement preventatively


HHS Assessments - 🧠 ANSWER ✔✔q1h:


- vital signs

- UOP

- labs

- neuro checks

- cardio assessment

- pulmonary assessment

- renal assessment

- whole body system


Hypoglycemia - 🧠 ANSWER ✔✔BG < 70


severe < 40


Mild Hypoglycemia s/s - 🧠 ANSWER ✔✔- sweating


- tremors

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