Test Bank for Lehne's Pharmacology for Nursing Care,
12th Edition | 2026 Update | A+ Graded
By Jacqueline Rosenjack Burchum, and Laura D. Rosenthal
,Table of Contents
UNIT I: INTRODUCTION............................................................................................................................ 7
Chapter 1: Orientation to Pharmacology .......................................................................................... 7
Chapter 2: Application of Pharmacology in Nursing Practice .......................................................... 25
Chapter 3: Drug Regulation, Development, Names, and Information ............................................. 42
UNIT II: BASIC PRINCIPLES OF PHARMACOLOGY .................................................................................... 56
Chapter 4. Pharmacokinetics ......................................................................................................... 56
Chapter 5: Pharmacodynamics....................................................................................................... 71
Chapter 6: Drug Interactions .......................................................................................................... 86
Chapter 7: Adverse Drug Reactions and Medication Errors .......................................................... 101
Chapter 8: Individual Variation in Drug Responses ....................................................................... 115
Chapter 9: Genetic and Genomic Considerations ......................................................................... 128
Chapter 10. Introduction to Immunomodulators.......................................................................... 140
UNIT III: DRUG THERAPY ACROSS THE LIFE SPAN ................................................................................. 154
Chapter 11: Drug Therapy During Pregnancy and Breastfeeding .................................................. 154
Chapter 12: Drug Therapy in Pediatric Patients ............................................................................ 167
Chapter 13: Drug Therapy in Older Adults .................................................................................... 180
UNIT IV: PERIPHERAL NERVOUS SYSTEM DRUGS .................................................................................. 193
SECTION 1: Introduction .................................................................................................................. 193
Chapter 14: Basic Principles of Neuropharmacology .................................................................... 193
Chapter 15: Physiology of the Peripheral Nervous System............................................................ 207
SECTION 2: Cholinergic Drugs .......................................................................................................... 221
Chapter 16: Muscarinic Agonists .................................................................................................. 221
Chapter 17: Muscarinic Antagonists ............................................................................................. 234
Chapter 18: Cholinesterase Inhibitors – Myasthenia Gravis .......................................................... 251
Chapter 19: Drugs that Block Nicotinic Cholinergic Transmission.................................................. 265
SECTION 3: Adrenergic Drugs ........................................................................................................... 280
Chapter 20: Adrenergic Agonists .................................................................................................. 280
Chapter 21: Adrenergic Antagonists ............................................................................................. 294
Chapter 22: Indirect-Acting Antiadrenergic Agents....................................................................... 310
UNIT V: CENTRAL NERVOUS SYSTEM DRUGS ....................................................................................... 324
SECTION 4: Introduction .................................................................................................................. 324
Chapter 23: Introduction to Central Nervous System Pharmacology ............................................ 324
, SECTION 5: Drugs for Neurodegenerative Disorders......................................................................... 341
Chapter 24: Drugs for Parkinson Disease ...................................................................................... 341
Chapter 25: Drugs for Alzheimer Disease ..................................................................................... 358
Chapter 26: Drugs for Multiple Sclerosis (MS) .............................................................................. 375
SECTION 6: Neurologic Drugs ........................................................................................................... 391
Chapter 27: Drugs for Seizure Disorders ....................................................................................... 391
Chapter 28: Drugs for Muscle Spasm and Spasticity ..................................................................... 407
SECTION 7: Drugs for Pain ................................................................................................................ 424
Chapter 29: Local Anesthetics ...................................................................................................... 424
Chapter 30: General Anesthetics .................................................................................................. 439
Chapter 31. Opioid Analgesics, Opioid Antagonists, and Nonopioid Centrally Acting Analgesics ... 455
Chapter 32. Pain Management in Patients with Cancer ................................................................ 473
Chapter 33. Drugs for Headaches ................................................................................................. 488
SECTION 8: Psychotherapeutic Drugs ............................................................................................... 504
Chapter 34: Antipsychotic Agents and Their Use in Schizophrenia ................................................ 504
Chapter 35: Antidepressants ........................................................................................................ 522
Chapter 36: Drugs for Bipolar Disorder ........................................................................................ 540
Chapter 37: Sedative-Hypnotic Drugs ........................................................................................... 557
Chapter 38: Management of Anxiety Disorder ............................................................................. 574
Chapter 39: Central Nervous System Stimulants and Attention-Deficit/Hyperactivity Disorder
(ADHD) ........................................................................................................................................ 591
SECTION 9: Substance Use Disorders ............................................................................................... 609
Chapter 40: Substance Use Disorders I: Basic Considerations ....................................................... 609
Chapter 41: Substance Use Disorders II: Alcohol .......................................................................... 626
Chapter 42: Substance Use Disorders III: Nicotine ........................................................................ 643
Chapter 43: Substance Use Disorders IV – Major Drugs of Abuse Other Than Alcohol and Nicotine
.................................................................................................................................................... 660
UNIT VI: DRUGS THAT AFFECT FLUID AND ELECTROLYTE BALANCE ...................................................... 678
Chapter 44: Diuretics ................................................................................................................... 678
Chapter 45: Agents Affecting the Volume and Ion Content of Body Fluids .................................... 696
UNIT VII: DRUGS THAT AFFECT THE HEART, BLOOD VESSELS, AND BLOOD ........................................... 714
Chapter 46: Review of Hemodynamics ......................................................................................... 714
Chapter 47: Drugs Acting on the Renin-Angiotensin-Aldosterone System (RAAS) ......................... 732
Chapter 48: Calcium Channel Blockers ......................................................................................... 749
, Chapter 49: Vasodilators .............................................................................................................. 766
Chapter 50: Drugs for Hypertension ............................................................................................. 783
Chapter 51: Drugs for Heart Failure ............................................................................................. 800
Chapter 52: Antidysrhythmic Drugs.............................................................................................. 817
Chapter 53: Drugs That Help Normalize Cholesterol and Triglyceride Levels ................................. 834
Chapter 54: Drugs for Angina Pectoris ......................................................................................... 851
Chapter 55: Anticoagulant, Antiplatelet, and Thrombolytic Drugs ................................................ 868
Chapter 56: Management of ST-Elevation Myocardial Infarction (STEMI) ..................................... 885
Chapter 57: Drugs for Hemophilia ................................................................................................ 902
Chapter 58: Drugs for Deficiency Anemias ................................................................................... 919
Chapter 59: Hematopoietic Agents .............................................................................................. 936
UNIT VIII: DRUGS FOR ENDOCRINE DISORDERS .................................................................................... 954
Chapter 60: Drugs for Diabetes Mellitus....................................................................................... 954
Chapter 61. Drugs for Thyroid Disorders ...................................................................................... 971
Chapter 62: Drugs Related to Hypothalamic and Pituitary Function ............................................. 988
Chapter 63: Drugs for Disorders of the Adrenal Cortex ............................................................... 1005
UNIT IX: REPRODUCTIVE HEALTH ....................................................................................................... 1021
Chapter 64: Estrogens and Progestins: Basic Pharmacology and Noncontraceptive Applications 1021
Chapter 65: Birth Control ........................................................................................................... 1035
Chapter 66: Drug Therapy of Infertility ....................................................................................... 1049
Chapter 67: Drugs That Affect Uterine Function ......................................................................... 1063
Chapter 68: Androgens .............................................................................................................. 1077
Chapter 69: Drugs for Erectile Dysfunction and Benign Prostatic Hyperplasia ............................. 1091
Chapter 70: Transgender Health ................................................................................................ 1104
UNIT X: ANTI-INFLAMMATORY, ANTIALLERGIC, AND IMMUNOLOGIC DRUGS .................................... 1122
Chapter 71. Review of the Immune System ................................................................................ 1122
Chapter 72: Childhood Immunization ......................................................................................... 1140
Chapter 73: Immunosuppressants ............................................................................................. 1157
Chapter 74: Antihistamines ........................................................................................................ 1174
Chapter 75: Cyclooxygenase Inhibitors – Nonsteroidal Anti-inflammatory Drugs (NSAIDs) and
Acetaminophen ......................................................................................................................... 1191
Chapter 76: Glucocorticoids in Nonendocrine Disorders ............................................................ 1208
UNIT XI: DRUGS FOR BONE AND JOINT DISORDERS ............................................................................ 1229
12th Edition | 2026 Update | A+ Graded
By Jacqueline Rosenjack Burchum, and Laura D. Rosenthal
,Table of Contents
UNIT I: INTRODUCTION............................................................................................................................ 7
Chapter 1: Orientation to Pharmacology .......................................................................................... 7
Chapter 2: Application of Pharmacology in Nursing Practice .......................................................... 25
Chapter 3: Drug Regulation, Development, Names, and Information ............................................. 42
UNIT II: BASIC PRINCIPLES OF PHARMACOLOGY .................................................................................... 56
Chapter 4. Pharmacokinetics ......................................................................................................... 56
Chapter 5: Pharmacodynamics....................................................................................................... 71
Chapter 6: Drug Interactions .......................................................................................................... 86
Chapter 7: Adverse Drug Reactions and Medication Errors .......................................................... 101
Chapter 8: Individual Variation in Drug Responses ....................................................................... 115
Chapter 9: Genetic and Genomic Considerations ......................................................................... 128
Chapter 10. Introduction to Immunomodulators.......................................................................... 140
UNIT III: DRUG THERAPY ACROSS THE LIFE SPAN ................................................................................. 154
Chapter 11: Drug Therapy During Pregnancy and Breastfeeding .................................................. 154
Chapter 12: Drug Therapy in Pediatric Patients ............................................................................ 167
Chapter 13: Drug Therapy in Older Adults .................................................................................... 180
UNIT IV: PERIPHERAL NERVOUS SYSTEM DRUGS .................................................................................. 193
SECTION 1: Introduction .................................................................................................................. 193
Chapter 14: Basic Principles of Neuropharmacology .................................................................... 193
Chapter 15: Physiology of the Peripheral Nervous System............................................................ 207
SECTION 2: Cholinergic Drugs .......................................................................................................... 221
Chapter 16: Muscarinic Agonists .................................................................................................. 221
Chapter 17: Muscarinic Antagonists ............................................................................................. 234
Chapter 18: Cholinesterase Inhibitors – Myasthenia Gravis .......................................................... 251
Chapter 19: Drugs that Block Nicotinic Cholinergic Transmission.................................................. 265
SECTION 3: Adrenergic Drugs ........................................................................................................... 280
Chapter 20: Adrenergic Agonists .................................................................................................. 280
Chapter 21: Adrenergic Antagonists ............................................................................................. 294
Chapter 22: Indirect-Acting Antiadrenergic Agents....................................................................... 310
UNIT V: CENTRAL NERVOUS SYSTEM DRUGS ....................................................................................... 324
SECTION 4: Introduction .................................................................................................................. 324
Chapter 23: Introduction to Central Nervous System Pharmacology ............................................ 324
, SECTION 5: Drugs for Neurodegenerative Disorders......................................................................... 341
Chapter 24: Drugs for Parkinson Disease ...................................................................................... 341
Chapter 25: Drugs for Alzheimer Disease ..................................................................................... 358
Chapter 26: Drugs for Multiple Sclerosis (MS) .............................................................................. 375
SECTION 6: Neurologic Drugs ........................................................................................................... 391
Chapter 27: Drugs for Seizure Disorders ....................................................................................... 391
Chapter 28: Drugs for Muscle Spasm and Spasticity ..................................................................... 407
SECTION 7: Drugs for Pain ................................................................................................................ 424
Chapter 29: Local Anesthetics ...................................................................................................... 424
Chapter 30: General Anesthetics .................................................................................................. 439
Chapter 31. Opioid Analgesics, Opioid Antagonists, and Nonopioid Centrally Acting Analgesics ... 455
Chapter 32. Pain Management in Patients with Cancer ................................................................ 473
Chapter 33. Drugs for Headaches ................................................................................................. 488
SECTION 8: Psychotherapeutic Drugs ............................................................................................... 504
Chapter 34: Antipsychotic Agents and Their Use in Schizophrenia ................................................ 504
Chapter 35: Antidepressants ........................................................................................................ 522
Chapter 36: Drugs for Bipolar Disorder ........................................................................................ 540
Chapter 37: Sedative-Hypnotic Drugs ........................................................................................... 557
Chapter 38: Management of Anxiety Disorder ............................................................................. 574
Chapter 39: Central Nervous System Stimulants and Attention-Deficit/Hyperactivity Disorder
(ADHD) ........................................................................................................................................ 591
SECTION 9: Substance Use Disorders ............................................................................................... 609
Chapter 40: Substance Use Disorders I: Basic Considerations ....................................................... 609
Chapter 41: Substance Use Disorders II: Alcohol .......................................................................... 626
Chapter 42: Substance Use Disorders III: Nicotine ........................................................................ 643
Chapter 43: Substance Use Disorders IV – Major Drugs of Abuse Other Than Alcohol and Nicotine
.................................................................................................................................................... 660
UNIT VI: DRUGS THAT AFFECT FLUID AND ELECTROLYTE BALANCE ...................................................... 678
Chapter 44: Diuretics ................................................................................................................... 678
Chapter 45: Agents Affecting the Volume and Ion Content of Body Fluids .................................... 696
UNIT VII: DRUGS THAT AFFECT THE HEART, BLOOD VESSELS, AND BLOOD ........................................... 714
Chapter 46: Review of Hemodynamics ......................................................................................... 714
Chapter 47: Drugs Acting on the Renin-Angiotensin-Aldosterone System (RAAS) ......................... 732
Chapter 48: Calcium Channel Blockers ......................................................................................... 749
, Chapter 49: Vasodilators .............................................................................................................. 766
Chapter 50: Drugs for Hypertension ............................................................................................. 783
Chapter 51: Drugs for Heart Failure ............................................................................................. 800
Chapter 52: Antidysrhythmic Drugs.............................................................................................. 817
Chapter 53: Drugs That Help Normalize Cholesterol and Triglyceride Levels ................................. 834
Chapter 54: Drugs for Angina Pectoris ......................................................................................... 851
Chapter 55: Anticoagulant, Antiplatelet, and Thrombolytic Drugs ................................................ 868
Chapter 56: Management of ST-Elevation Myocardial Infarction (STEMI) ..................................... 885
Chapter 57: Drugs for Hemophilia ................................................................................................ 902
Chapter 58: Drugs for Deficiency Anemias ................................................................................... 919
Chapter 59: Hematopoietic Agents .............................................................................................. 936
UNIT VIII: DRUGS FOR ENDOCRINE DISORDERS .................................................................................... 954
Chapter 60: Drugs for Diabetes Mellitus....................................................................................... 954
Chapter 61. Drugs for Thyroid Disorders ...................................................................................... 971
Chapter 62: Drugs Related to Hypothalamic and Pituitary Function ............................................. 988
Chapter 63: Drugs for Disorders of the Adrenal Cortex ............................................................... 1005
UNIT IX: REPRODUCTIVE HEALTH ....................................................................................................... 1021
Chapter 64: Estrogens and Progestins: Basic Pharmacology and Noncontraceptive Applications 1021
Chapter 65: Birth Control ........................................................................................................... 1035
Chapter 66: Drug Therapy of Infertility ....................................................................................... 1049
Chapter 67: Drugs That Affect Uterine Function ......................................................................... 1063
Chapter 68: Androgens .............................................................................................................. 1077
Chapter 69: Drugs for Erectile Dysfunction and Benign Prostatic Hyperplasia ............................. 1091
Chapter 70: Transgender Health ................................................................................................ 1104
UNIT X: ANTI-INFLAMMATORY, ANTIALLERGIC, AND IMMUNOLOGIC DRUGS .................................... 1122
Chapter 71. Review of the Immune System ................................................................................ 1122
Chapter 72: Childhood Immunization ......................................................................................... 1140
Chapter 73: Immunosuppressants ............................................................................................. 1157
Chapter 74: Antihistamines ........................................................................................................ 1174
Chapter 75: Cyclooxygenase Inhibitors – Nonsteroidal Anti-inflammatory Drugs (NSAIDs) and
Acetaminophen ......................................................................................................................... 1191
Chapter 76: Glucocorticoids in Nonendocrine Disorders ............................................................ 1208
UNIT XI: DRUGS FOR BONE AND JOINT DISORDERS ............................................................................ 1229
