WGU D116 ADVANCED PHARMACOLOGY OBJECTIVE
ASSESSMENT ACTUAL Comprehensive Resource To Help
You Ace 2026-2027 Includes Frequently Tested Questions
With ELABORATED 100% Correct COMPLETE SOLUTIONS
Guaranteed Pass First Attempt!!
Current Update!!
1. What does neuropharmacology study?
How drugs affect the nervous system to modify behavior, cognition, and
physiological function.
2. What is molecular neuropharmacology?
Drug interactions at the receptor and intracellular signaling level.
3. What is behavioral neuropharmacology?
The effects of drugs on behavior and mental states.
4. What is the role of acetylcholine (ACh)?
Memory, attention, and autonomic regulation.
5. What is the role of dopamine (DA)?
Reward, motivation, and motor control.
,6. What is the role of serotonin (5-HT)?
Mood regulation, sleep, pain modulation, and GI function.
7. What is the role of norepinephrine (NE)?
Arousal, stress response, attention, and blood pressure regulation.
8. What is the role of GABA?
Primary inhibitory neurotransmitter; seizure control.
9. What is the role of glutamate?
Learning, memory, and excitatory neurotransmission (excitotoxicity).
10.What are cholinergic drugs?
Drugs that affect acetylcholine receptors (agonists, anticholinesterases,
anticholinergics).
11.What are dopaminergic agents?
Drugs that modify dopamine pathways (agonists, antagonists, reuptake
inhibitors).
12.What are serotonergic agents?
Drugs that alter serotonin levels (SSRIs, SNRIs, agonists, antagonists).
,13.What are GABAergic agents?
Drugs that enhance GABA activity (GABA-A agonists, GABA analogs).
14.What are glutamatergic modulators?
Drugs that affect glutamate receptors (NMDA antagonists, AMPA
modulators).
15.What neurotransmitter deficit causes Parkinson’s disease?
Decreased dopamine in the substantia nigra.
Treatment: Levodopa, dopamine agonists.
16.What neurotransmitter deficit causes Alzheimer’s disease?
Decreased acetylcholine with amyloid plaques and tau tangles.
Treatment: Cholinesterase inhibitors.
17.What is the pathophysiology of epilepsy?
Excess neuronal firing.
Treatment: GABA enhancers, sodium channel blockers.
18.What causes depression neurochemically?
Decreased monoamines (serotonin, norepinephrine, dopamine).
Treatment: SSRIs, SNRIs.
19.What causes anxiety disorders?
, Hyperactivity of the limbic system.
Treatment: SSRIs, benzodiazepines.
20.What neurotransmitter abnormality occurs in schizophrenia?
Increased dopamine in the mesolimbic pathway.
Treatment: D2 receptor antagonists.
21.What is the neurochemical basis of migraine?
Serotonin and vascular dysregulation.
Treatment: Triptans, beta blockers.
22.What causes multiple sclerosis?
Autoimmune demyelination of CNS neurons.
Treatment: Immunomodulators, corticosteroids.
23.What should be monitored with antipsychotics?
Extrapyramidal symptoms, QT prolongation, hyperprolactinemia.
24.What are major side effects of SSRIs/SNRIs?
Sexual dysfunction, serotonin syndrome.
25.What dietary interaction is dangerous with MAOIs?
Tyramine → hypertensive crisis.
ASSESSMENT ACTUAL Comprehensive Resource To Help
You Ace 2026-2027 Includes Frequently Tested Questions
With ELABORATED 100% Correct COMPLETE SOLUTIONS
Guaranteed Pass First Attempt!!
Current Update!!
1. What does neuropharmacology study?
How drugs affect the nervous system to modify behavior, cognition, and
physiological function.
2. What is molecular neuropharmacology?
Drug interactions at the receptor and intracellular signaling level.
3. What is behavioral neuropharmacology?
The effects of drugs on behavior and mental states.
4. What is the role of acetylcholine (ACh)?
Memory, attention, and autonomic regulation.
5. What is the role of dopamine (DA)?
Reward, motivation, and motor control.
,6. What is the role of serotonin (5-HT)?
Mood regulation, sleep, pain modulation, and GI function.
7. What is the role of norepinephrine (NE)?
Arousal, stress response, attention, and blood pressure regulation.
8. What is the role of GABA?
Primary inhibitory neurotransmitter; seizure control.
9. What is the role of glutamate?
Learning, memory, and excitatory neurotransmission (excitotoxicity).
10.What are cholinergic drugs?
Drugs that affect acetylcholine receptors (agonists, anticholinesterases,
anticholinergics).
11.What are dopaminergic agents?
Drugs that modify dopamine pathways (agonists, antagonists, reuptake
inhibitors).
12.What are serotonergic agents?
Drugs that alter serotonin levels (SSRIs, SNRIs, agonists, antagonists).
,13.What are GABAergic agents?
Drugs that enhance GABA activity (GABA-A agonists, GABA analogs).
14.What are glutamatergic modulators?
Drugs that affect glutamate receptors (NMDA antagonists, AMPA
modulators).
15.What neurotransmitter deficit causes Parkinson’s disease?
Decreased dopamine in the substantia nigra.
Treatment: Levodopa, dopamine agonists.
16.What neurotransmitter deficit causes Alzheimer’s disease?
Decreased acetylcholine with amyloid plaques and tau tangles.
Treatment: Cholinesterase inhibitors.
17.What is the pathophysiology of epilepsy?
Excess neuronal firing.
Treatment: GABA enhancers, sodium channel blockers.
18.What causes depression neurochemically?
Decreased monoamines (serotonin, norepinephrine, dopamine).
Treatment: SSRIs, SNRIs.
19.What causes anxiety disorders?
, Hyperactivity of the limbic system.
Treatment: SSRIs, benzodiazepines.
20.What neurotransmitter abnormality occurs in schizophrenia?
Increased dopamine in the mesolimbic pathway.
Treatment: D2 receptor antagonists.
21.What is the neurochemical basis of migraine?
Serotonin and vascular dysregulation.
Treatment: Triptans, beta blockers.
22.What causes multiple sclerosis?
Autoimmune demyelination of CNS neurons.
Treatment: Immunomodulators, corticosteroids.
23.What should be monitored with antipsychotics?
Extrapyramidal symptoms, QT prolongation, hyperprolactinemia.
24.What are major side effects of SSRIs/SNRIs?
Sexual dysfunction, serotonin syndrome.
25.What dietary interaction is dangerous with MAOIs?
Tyramine → hypertensive crisis.
