WGU D116 ADVANCED PHARMACOLOGY OBJECTIVE
ASSESSMENT ACTUAL Comprehensive Resource To
Help You Ace 2026-2027 Includes Frequently Tested
Questions With ELABORATED 100% Correct
COMPLETE SOLUTIONS
Guaranteed Pass First Attempt!!
Current Update!!
1. How does Narcan work?
Correct Answer: -Preventing activation of opioid receptors through antagonist
actions
-blocking the action of opioids at opioid receptors.
2. The nurse is preparing to administer penicillin G intramuscularly to a child.
The child's parents ask why the drug cannot be given in an oral liquid form.
What is the nurse's reply?
Correct Answer: "This drug would be inactivated by enzymes in the stomach."
3. A patient taking three medications for hypertension is diagnosed with
chronic obstructive pulmonary disease (COPD).
Which action should be taken prior to prescribing medications to treat
COPD?
Correct Answer: Obtain a complete medication history
, 4. A patient with chronic pain calls the provider's office to request a refill for
oxycodone.
Which action is most appropriate?
Correct Answer: Schedule an appointment with the patient
5. Are schedule 2 medications eligible for refills?
Correct Answer: No!
* Prescriptions must be in a hard script; therefore, the patient must be evaluated
in person.
6. A patient is using a metered-dose inhaler containing albuterol for asthma.
The medication label instructs the patient to administer "two puffs every 4
hours as needed for coughing or wheezing."
The patient reports feeling jittery sometimes when taking the medication,
and she does not feel that the medication is always effective.
Which action is most appropriate?
Correct Answer: Auscultating the patient's lung sounds and obtaining vital signs
7. Ipratropium bromide is a quaternary ammonium derivative of the prototype
drug atropine. It is used for bronchodilation.
Why would a medicinal chemist want to alter this prototype?
Correct Answer: To allow for higher doses to be delivered
8. How does Ipratropium bromine cause greater bronchodilation?
Correct Answer: -higher doses can be achieved with less systemic absorption and
less permeation across the blood-brain barrier.
-resulting in greater bronchodilation with less toxicity from systemic absorption
,9. Which drugs are classified as PDE5 inhibitors?
Correct Answer: -fil denotes it is in the PDE5 family of drugs
ex. Sildenafil, Tadalafil
10. Explain the blood-brain barrier
Correct Answer: prevents highly ionized and protein-bound drugs from crossing
into the CNS and allows lipid-soluble drugs and those that can cross via specific
transport systems to enter.
11. A group of nursing students asks a nurse to explain the blood-brain barrier.
The nurse would be correct to say that the blood-brain barrier does what?
Correct Answer: prevents some potentially toxic substances from crossing into the
central nervous system
12. What is different about infants and their blood-brain barriers compared to
adults?
Correct Answer: he blood-brain barrier in infants is not fully developed, so infants
are more sensitive to CNS drugs and often require lower doses
13. A pregnant patient is in premature labor.
Which class of drug will she be given?
Correct Answer: Beta2 agonist
14. How do Beta2 agonists work?
, Correct Answer: cause relaxation of uterine muscles, slowing or stopping the
contractions that precipitate labor.
15. A nurse is explaining the activation of beta-2 receptors to nursing students
during a clinical rotation at the hospital.
Which statement by a student demonstrates a need for further teaching?
Correct Answer: "Beta-2 activation results in contraction of the uterine muscle."
16. A provider is teaching a patient about a medication that alters the sympathetic
nervous system functions. To evaluate understanding, the provider asks the
patient to describe which functions the sympathetic nervous system regulates.
Which answer indicates the need for further teaching?
Correct Answer: The digestive functions of the body
17. A patient is experiencing toxic side effects from atropine, including delirium
and hallucinations.
Which medication will the provider ask the nurse to administer?
Correct Answer: Physostigmine
18. A patient who has myasthenia gravis will be taking neostigmine.
What should the nurse emphasize when teaching this patient about the
medication?
Correct Answer: "Take a supplementary dose before exercise."
19. You have ordered pilocarpine. You understand that the drug stimulates
muscarinic receptors.
Which action would you expect the drug to have?
ASSESSMENT ACTUAL Comprehensive Resource To
Help You Ace 2026-2027 Includes Frequently Tested
Questions With ELABORATED 100% Correct
COMPLETE SOLUTIONS
Guaranteed Pass First Attempt!!
Current Update!!
1. How does Narcan work?
Correct Answer: -Preventing activation of opioid receptors through antagonist
actions
-blocking the action of opioids at opioid receptors.
2. The nurse is preparing to administer penicillin G intramuscularly to a child.
The child's parents ask why the drug cannot be given in an oral liquid form.
What is the nurse's reply?
Correct Answer: "This drug would be inactivated by enzymes in the stomach."
3. A patient taking three medications for hypertension is diagnosed with
chronic obstructive pulmonary disease (COPD).
Which action should be taken prior to prescribing medications to treat
COPD?
Correct Answer: Obtain a complete medication history
, 4. A patient with chronic pain calls the provider's office to request a refill for
oxycodone.
Which action is most appropriate?
Correct Answer: Schedule an appointment with the patient
5. Are schedule 2 medications eligible for refills?
Correct Answer: No!
* Prescriptions must be in a hard script; therefore, the patient must be evaluated
in person.
6. A patient is using a metered-dose inhaler containing albuterol for asthma.
The medication label instructs the patient to administer "two puffs every 4
hours as needed for coughing or wheezing."
The patient reports feeling jittery sometimes when taking the medication,
and she does not feel that the medication is always effective.
Which action is most appropriate?
Correct Answer: Auscultating the patient's lung sounds and obtaining vital signs
7. Ipratropium bromide is a quaternary ammonium derivative of the prototype
drug atropine. It is used for bronchodilation.
Why would a medicinal chemist want to alter this prototype?
Correct Answer: To allow for higher doses to be delivered
8. How does Ipratropium bromine cause greater bronchodilation?
Correct Answer: -higher doses can be achieved with less systemic absorption and
less permeation across the blood-brain barrier.
-resulting in greater bronchodilation with less toxicity from systemic absorption
,9. Which drugs are classified as PDE5 inhibitors?
Correct Answer: -fil denotes it is in the PDE5 family of drugs
ex. Sildenafil, Tadalafil
10. Explain the blood-brain barrier
Correct Answer: prevents highly ionized and protein-bound drugs from crossing
into the CNS and allows lipid-soluble drugs and those that can cross via specific
transport systems to enter.
11. A group of nursing students asks a nurse to explain the blood-brain barrier.
The nurse would be correct to say that the blood-brain barrier does what?
Correct Answer: prevents some potentially toxic substances from crossing into the
central nervous system
12. What is different about infants and their blood-brain barriers compared to
adults?
Correct Answer: he blood-brain barrier in infants is not fully developed, so infants
are more sensitive to CNS drugs and often require lower doses
13. A pregnant patient is in premature labor.
Which class of drug will she be given?
Correct Answer: Beta2 agonist
14. How do Beta2 agonists work?
, Correct Answer: cause relaxation of uterine muscles, slowing or stopping the
contractions that precipitate labor.
15. A nurse is explaining the activation of beta-2 receptors to nursing students
during a clinical rotation at the hospital.
Which statement by a student demonstrates a need for further teaching?
Correct Answer: "Beta-2 activation results in contraction of the uterine muscle."
16. A provider is teaching a patient about a medication that alters the sympathetic
nervous system functions. To evaluate understanding, the provider asks the
patient to describe which functions the sympathetic nervous system regulates.
Which answer indicates the need for further teaching?
Correct Answer: The digestive functions of the body
17. A patient is experiencing toxic side effects from atropine, including delirium
and hallucinations.
Which medication will the provider ask the nurse to administer?
Correct Answer: Physostigmine
18. A patient who has myasthenia gravis will be taking neostigmine.
What should the nurse emphasize when teaching this patient about the
medication?
Correct Answer: "Take a supplementary dose before exercise."
19. You have ordered pilocarpine. You understand that the drug stimulates
muscarinic receptors.
Which action would you expect the drug to have?
