ATI PN
PHARMACOLOGY
VERSION 1, 2 & 3 EXAM
(NGN-STYLE QUESTIONS & CASE “SCENARIO”)
Actual Qs & Ans to Pass the Exam
This ATI test contains:
, Passing Score Guarantee
Each Exam has 70 PHARMACOLOGY nursing questions
multiple-choice format (A, B, C, D) with correct answers
structured rationales.
incorporate Next Generation NCLEX (NGN)-style.
Some questions feature brief “scenario” elements and rationales.
Table of Contents
ATI PN PHARMACOLOGY EXAM V1..........................................................................................2
ATI PN PHARMACOLOGY EXAM V2........................................................................................30
ATI PN PHARMACOLOGY EXAM V3........................................................................................64
ATI PN PHARMACOLOGY EXAM V1
1. A nurse is reinforcing teaching with a client who has a new prescription for omeprazole oral
capsules. Which of the following instructions should the nurse include?
a. Chew the medication thoroughly before swallowing
b. Swallow the medication whole
,c. Crush the capsules and mix with food
d. Take the medication with an antacid
Answer: b. Swallow the medication whole
Expert Rationale: The nurse should instruct the client to swallow omeprazole capsules whole as it is
available in delayed-release form. Chewing or crushing the medication can destroy the coating and reduce
effectiveness. Omeprazole is a proton pump inhibitor that blocks gastric acid secretion and must be
absorbed intact.
---
2. A nurse is reinforcing teaching about comfort measures with the guardian of a 10-year-old child
who has a viral infection. The nurse should plan to tell the parent that aspirin is contraindicated
because of the risk for which of the following conditions?
a. Hemophilia
b. Reye syndrome
c. Appendicitis
d. Anaphylaxis
Answer: b. Reye syndrome
Expert Rationale: Aspirin is contraindicated in children and adolescents with viral infections due to the
increased risk of Reye syndrome, a rare but potentially fatal condition causing encephalopathy and liver
damage.
---
3. A nurse is caring for a client who has a prescription for an IM injection of penicillin G benzathine.
The client asks why the injection must be given IM instead of through the IV line. Which of the
following responses should the nurse make?
a. "IV administration causes an allergic reaction."
b. "Your medication can't be given IV because it is not water-soluble."
c. "IV doses are usually lower than IM doses."
, d. "IM provides faster absorption than IV."
Answer: b. "Your medication can't be given IV because it is not water-soluble."
Expert Rationale: Penicillin G benzathine is poorly water-soluble; administering it IV can cause serious
reactions such as embolism. It is formulated for slow absorption from the IM site.
---
4. A nurse is planning to reinforce teaching about newborn immunizations with a client who is 24 hr
postpartum. Which of the following information should the nurse plan to include?
a. "Your baby will receive the first hepatitis B vaccine before discharge."
b. "Your baby will receive the MMR vaccine before discharge."
c. "Your baby will receive the varicella vaccine before discharge."
d. "Your baby will receive the flu vaccine before discharge."
Answer: a. "Your baby will receive the first hepatitis B vaccine before discharge."
Expert Rationale: The newborn should receive the first dose of the hepatitis B vaccine within 24 hours of
birth to provide early immunity against hepatitis B infection.
---
5. A client comes to an urgent care clinic and announces with great enthusiasm, "I am an expert at
all things medical as they apply to me, and I require zolpidem." The client's pupils are dilated, along
with an elevated heart rate and blood pressure level. The nurse should suspect intoxication with
which of the following substances?
a. Alcohol
b. Heroin
c. Cocaine
d. Benzodiazepines
Answer: c. Cocaine
PHARMACOLOGY
VERSION 1, 2 & 3 EXAM
(NGN-STYLE QUESTIONS & CASE “SCENARIO”)
Actual Qs & Ans to Pass the Exam
This ATI test contains:
, Passing Score Guarantee
Each Exam has 70 PHARMACOLOGY nursing questions
multiple-choice format (A, B, C, D) with correct answers
structured rationales.
incorporate Next Generation NCLEX (NGN)-style.
Some questions feature brief “scenario” elements and rationales.
Table of Contents
ATI PN PHARMACOLOGY EXAM V1..........................................................................................2
ATI PN PHARMACOLOGY EXAM V2........................................................................................30
ATI PN PHARMACOLOGY EXAM V3........................................................................................64
ATI PN PHARMACOLOGY EXAM V1
1. A nurse is reinforcing teaching with a client who has a new prescription for omeprazole oral
capsules. Which of the following instructions should the nurse include?
a. Chew the medication thoroughly before swallowing
b. Swallow the medication whole
,c. Crush the capsules and mix with food
d. Take the medication with an antacid
Answer: b. Swallow the medication whole
Expert Rationale: The nurse should instruct the client to swallow omeprazole capsules whole as it is
available in delayed-release form. Chewing or crushing the medication can destroy the coating and reduce
effectiveness. Omeprazole is a proton pump inhibitor that blocks gastric acid secretion and must be
absorbed intact.
---
2. A nurse is reinforcing teaching about comfort measures with the guardian of a 10-year-old child
who has a viral infection. The nurse should plan to tell the parent that aspirin is contraindicated
because of the risk for which of the following conditions?
a. Hemophilia
b. Reye syndrome
c. Appendicitis
d. Anaphylaxis
Answer: b. Reye syndrome
Expert Rationale: Aspirin is contraindicated in children and adolescents with viral infections due to the
increased risk of Reye syndrome, a rare but potentially fatal condition causing encephalopathy and liver
damage.
---
3. A nurse is caring for a client who has a prescription for an IM injection of penicillin G benzathine.
The client asks why the injection must be given IM instead of through the IV line. Which of the
following responses should the nurse make?
a. "IV administration causes an allergic reaction."
b. "Your medication can't be given IV because it is not water-soluble."
c. "IV doses are usually lower than IM doses."
, d. "IM provides faster absorption than IV."
Answer: b. "Your medication can't be given IV because it is not water-soluble."
Expert Rationale: Penicillin G benzathine is poorly water-soluble; administering it IV can cause serious
reactions such as embolism. It is formulated for slow absorption from the IM site.
---
4. A nurse is planning to reinforce teaching about newborn immunizations with a client who is 24 hr
postpartum. Which of the following information should the nurse plan to include?
a. "Your baby will receive the first hepatitis B vaccine before discharge."
b. "Your baby will receive the MMR vaccine before discharge."
c. "Your baby will receive the varicella vaccine before discharge."
d. "Your baby will receive the flu vaccine before discharge."
Answer: a. "Your baby will receive the first hepatitis B vaccine before discharge."
Expert Rationale: The newborn should receive the first dose of the hepatitis B vaccine within 24 hours of
birth to provide early immunity against hepatitis B infection.
---
5. A client comes to an urgent care clinic and announces with great enthusiasm, "I am an expert at
all things medical as they apply to me, and I require zolpidem." The client's pupils are dilated, along
with an elevated heart rate and blood pressure level. The nurse should suspect intoxication with
which of the following substances?
a. Alcohol
b. Heroin
c. Cocaine
d. Benzodiazepines
Answer: c. Cocaine
