HESI RN AdvANcEd PHARmAcology ExAm Study
guIdE 2026 – comPlEtE PRActIcE QuEStIoNS,
vERIfIEd RAtIoNAlES, dRug clASS BREAkdowN,
NuRSINg PHARmAcology REvIEw & HESI RN tESt
SuccESS mAtERIAlS
HESI RN Advanced Pharmacology Exam
Question 1:
Which class of medications is primarily used to lower blood pressure by inhibiting the
angiotensin-converting enzyme (ACE)?
• A) Beta-Blockers
• B) ACE Inhibitors
• C) Calcium Channel Blockers
• D) Diuretics
Correct Option: B (ACE Inhibitors)
Rationale:
ACE inhibitors lower blood pressure by preventing the conversion of angiotensin I to
angiotensin II, which causes vasodilation and decreases blood volume, leading to reduced blood
pressure.
Question 2:
What is the primary action of tPA (tissue Plasminogen Activator) in a patient experiencing an
acute ischemic stroke?
• A) Anticoagulation
• B) Thrombolysis
• C) Platelet aggregation
• D) Vasoconstriction
Correct Option: B (Thrombolysis)
Rationale:
tPA is a thrombolytic agent that dissolves blood clots by converting plasminogen to plasmin, thus
restoring blood flow to the affected area.
, Question 3:
Which of the following medications is contraindicated in patients with a history of asthma?
• A) Metoprolol
• B) Lisinopril
• C) Propranolol
• D) Diltiazem
Correct Option: C (Propranolol)
Rationale:
Propranolol is a non-selective beta-blocker that can cause bronchoconstriction and is therefore
contraindicated in patients with asthma.
Question 4:
What lab value must be monitored regularly in patients taking warfarin?
• A) Potassium levels
• B) Liver function tests
• C) INR (International Normalized Ratio)
• D) CBC (Complete Blood Count)
Correct Option: C (INR)
Rationale:
The INR is crucial to monitor the effectiveness of warfarin therapy and ensures that the level of
anticoagulation is within the safe and therapeutic range.
Question 5:
What is the primary purpose of administering an antibiotic such as ciprofloxacin?
• A) Pain relief
• B) Reducing inflammation
• C) Treating bacterial infections
• D) Preventing viral infections
Correct Option: C (Treating bacterial infections)
guIdE 2026 – comPlEtE PRActIcE QuEStIoNS,
vERIfIEd RAtIoNAlES, dRug clASS BREAkdowN,
NuRSINg PHARmAcology REvIEw & HESI RN tESt
SuccESS mAtERIAlS
HESI RN Advanced Pharmacology Exam
Question 1:
Which class of medications is primarily used to lower blood pressure by inhibiting the
angiotensin-converting enzyme (ACE)?
• A) Beta-Blockers
• B) ACE Inhibitors
• C) Calcium Channel Blockers
• D) Diuretics
Correct Option: B (ACE Inhibitors)
Rationale:
ACE inhibitors lower blood pressure by preventing the conversion of angiotensin I to
angiotensin II, which causes vasodilation and decreases blood volume, leading to reduced blood
pressure.
Question 2:
What is the primary action of tPA (tissue Plasminogen Activator) in a patient experiencing an
acute ischemic stroke?
• A) Anticoagulation
• B) Thrombolysis
• C) Platelet aggregation
• D) Vasoconstriction
Correct Option: B (Thrombolysis)
Rationale:
tPA is a thrombolytic agent that dissolves blood clots by converting plasminogen to plasmin, thus
restoring blood flow to the affected area.
, Question 3:
Which of the following medications is contraindicated in patients with a history of asthma?
• A) Metoprolol
• B) Lisinopril
• C) Propranolol
• D) Diltiazem
Correct Option: C (Propranolol)
Rationale:
Propranolol is a non-selective beta-blocker that can cause bronchoconstriction and is therefore
contraindicated in patients with asthma.
Question 4:
What lab value must be monitored regularly in patients taking warfarin?
• A) Potassium levels
• B) Liver function tests
• C) INR (International Normalized Ratio)
• D) CBC (Complete Blood Count)
Correct Option: C (INR)
Rationale:
The INR is crucial to monitor the effectiveness of warfarin therapy and ensures that the level of
anticoagulation is within the safe and therapeutic range.
Question 5:
What is the primary purpose of administering an antibiotic such as ciprofloxacin?
• A) Pain relief
• B) Reducing inflammation
• C) Treating bacterial infections
• D) Preventing viral infections
Correct Option: C (Treating bacterial infections)
