VERIFIED ANSWERS
What is the maturation and life cycle of enterocytes (crypts, villi, sloughing etc.) - correct answer The crypts
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which located in the pits of villi contain stem cells that can differentiate to enterocytes, and the enterocytes
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mature as they migrate up. The life cycle of enterocytes is 72 hours. Once enterocytes have reached the top of
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villi, they are sloughed off, and are either digested or excreted in feces.
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Uptake - correct answer compounds being transported into enterocytes
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Absorption - correct answer compounds being transported from enterocytes into circulation/lymph
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Passive Transport - correct answer does not require energy from ATP, and moves with concentration gradient
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1. Simple diffusion - solutes move from an area of higher concentration to an area of lower concentration
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without the aid of proteins in membrane
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2. Facilitated diffusion - solutes move from an area of higher concentration to an area of lower concentration
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with assistance of membrane proteins
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3. Osmosis - water moves from an area of lower concentration to an area of higher concentration
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Active transport - correct answer requires energy in the form of ATP, and moves against concentration
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gradient
1. Active carrier transport - solutes move from an area of lower concentration to an area of higher
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concentration, use carrier/transport protein to help compounds get across membrane a a a a a a a a a
, Endocytosis - correct answer substances are taken up into cell in vesicles formed from the cell membrane
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Type 1 Diabetes - correct answer the beta cells in pancreas are not capable of producing enough insulin, so it
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doesn't bind to the insulin receptors and thus does not activate GLUT 4 to move to the surface of muscle and
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adipose cells. This means limited glucose is taken up by GLUT 4.
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Type 2 Diabetes - correct answer enough insulin is produced by pancreatic beta cells and binds to the insulin
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receptor, GLUT4 does not move to the surface of muscle and adipose cells due to the insulin-resistance, as a
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result, little glucose is taken up into cell
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Glycemic Index - correct answer the relative change in blood glucose after consumption of 50g of
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carbohydrates in a test food compared to 50g of carbohydrates of reference food (white bread or glucose)
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Glycemic Load - correct answer incorporates serving size, use if you are measuring a whole food that takes
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into account serving size
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How Carbs are taken up into enterocytes, altered or repackaged, and absorbed - correct answer
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Monosaccharides are taken up through transporters a a a a a
How Proteins are taken up into enterocytes, altered or repackaged, and absorbed - correct answer Dipeptides
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and tripeptides are transported through a transporter, and amino acids are taken up through a variety of
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transporters. Inside the enterocytes, peptides are cleaved to amino acids by peptidases. Then all amino acids
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are transported from enterocytes into capillaries
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How Lipids are taken up into enterocytes, altered or repackaged, and absorbed - correct answer Mixed
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Micelles make it to the brush border, components make it into the enterocyte. SCFA and MCFAs are not
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reesterfied and are diffused into the capillaries and bind to the protein Albumin. Long Chain Fatty Acids are
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reesterified into phosphatidylcholine, triglycerides, and cholesterol ester and are packaged into
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chylomicrons and absorbed through the lacteal because they are too large for capillaries.
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How Carbs are transported to the liver after absorption - correct answer Monosaccharides are transported to
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the liver through the portal vein.
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