Exam 5-NUR 3420- Pharmacology
Study Guide Exam with Actual
Detailed Answers 2025-2026 Edition.
A nurse is planning care for a client who is receiving chemotherapy and has a new prescription
for ondansetron. Which of the following actions should the nurse plan to take (Select All that
apply)
A) Infuse the drug 30 min prior to chemotherapy
B) Administer the drug when the client reports nausea
C) Infuse the drug slowly over 15 min
D) Administer the drug immediately following chemotherapy
E) Repeat the dose 4 hr after chemotherapy. - Answer A) Infuse the drug 30 min prior to
chemotherapy
The nurse should administer IV ondansetron, a serotonin antagonist, 30 min prior to
chemotherapy to prevent chemotherapy-induced nausea and vomiting. When treating
radiation-induced nausea and vomiting, the nurse should give the drug orally 1 to 2 hours prior
to radiation therapy and again every 8 hr.
C) Infuse the drug slowly over 15 min
The nurse should infuse ondansetron slowly over 15 min to prevent chemotherapy-induced
nausea
E) Repeat the dose 4 hr after chemotherapy
For maximum effectiveness, the nurse should administer ondansetron 4 hr after chemotherapy,
and again 8 hr after chemotherapy. When treating anesthesia-induced nausea and vomiting the
nurse can give the drug 1 hr before anesthesia induction
A nurse is caring for a client who has a new prescription for alosetron to treat irritable bowel
syndrome. The nurse should instruct the client to report which of the following adverse effects
of the drug?
A) Headache
B) Drowsiness
,C)Abdominal Pain
D) Sore Throat - Answer C)Abdominal Pain
Alosetron, a serotonin 5-HT3 receptor antagonist, can cause ischemic colitis. The nurse should
tell the client to report abdominal pain, bloody diarrhea, or rectal bleeding, and stop taking the
drug if these manifestation occur.
A nurse is caring for an older adult client who has kidney disease and a new prescription for
cimetidine. The nurse should instruct the client to report which of the following manifestations?
A) Lethargy
B) Cellulitis
C) Dry mouth
D) Myalgia - Answer A) Lethargy
Cimetidine is a histamine2 receptor antagonist, which can potentially cross the blood-brain
barrier. Older adults who have kidney impairments are at risk for central nervous system (CNS)
effects such as lethargy, depression, confusion, and seizures. The nurse should instruct the
client to report these manifestations to their provider
Which of the following drugs has protocols that require clients to meet specific risk-
management criteria and sign a treatment agreement before the nurse can administer the
drug?
A) Lubiprostone
B) Azathioprine
C) Sulfasalazine
D) Alosetron - Answer D) Alosetron
Clients who take alosteron, a serotonin 5-HT3 receptor antagonist, can develop severe
constipation that can lead to impaction, bowel obstruction, perforation, and potentially fatal
ischemic colitis. Because of these risks, nurses must inform clients of the benefits and risks oft
eh drug therapy, and clients must sign a treatment agreement
A nurse is teaching a client who has a new prescription for methotrexate. The nurse should
instruct the client to monitor for manifestations of which of the following conditions?
A) Gout
B) Constipation
, C) Insomnia
D) Hursutism - Answer A) Gout
An adverse effect of methotrexate is hyperuricemia, which causes gout, The nurse should
instruct the client to drink plenty of fluids to minimize this effect, and to report edema or pain
the joints.
A nurse is teaching a client who has a new prescription for sulfasalazine. Which of the following
statements should the nurse make?
A) "Use sunscreen and protective clothing while taking sulfasalazine to prevent sunburn."
B) "The medication can stain your contact lenses green."
C) "The medication can color your urine dark brown"
D) "Take an iron supplement when you take sulfasalazine to prevent anemia" - Answer A)
"Use sunscreen and protective clothing while taking sulfasalazine to prevent sunburn."
Photosensitivity is a possible adverse effect of sulfasalazine that makes the skin sensitive to
light. The nurse should instruct the client to wear sunscreen and protective clothing when
outdoors to prevent burning
A nurse is teaching a client who recently had a myocardial infarction and has a new prescription
for docusate sodium. The nurse should inform the client that docusate sodium has which of the
following therapeutic effects?
A) Reduces inflammation
B) Reduces gastric acid
C) Prevent diarrhea
D) Prevents straining - Answer D) Prevents straining
Docusate sodium, a stool softener, prevents straining during defection and prevents the
elevation in blood pressure that can result from straining. It also helps relieve constipation and
reduces the painful elimination of hard stools
A nurse is caring for a client who has a new prescription for famotidine to treat GERD. The nurse
should instruct the client to wait at least 1 hr between taking famotidine and which of the
following over-the-counter drugs?
A) Ginkgo biloba
B) Antidiarrheals
Study Guide Exam with Actual
Detailed Answers 2025-2026 Edition.
A nurse is planning care for a client who is receiving chemotherapy and has a new prescription
for ondansetron. Which of the following actions should the nurse plan to take (Select All that
apply)
A) Infuse the drug 30 min prior to chemotherapy
B) Administer the drug when the client reports nausea
C) Infuse the drug slowly over 15 min
D) Administer the drug immediately following chemotherapy
E) Repeat the dose 4 hr after chemotherapy. - Answer A) Infuse the drug 30 min prior to
chemotherapy
The nurse should administer IV ondansetron, a serotonin antagonist, 30 min prior to
chemotherapy to prevent chemotherapy-induced nausea and vomiting. When treating
radiation-induced nausea and vomiting, the nurse should give the drug orally 1 to 2 hours prior
to radiation therapy and again every 8 hr.
C) Infuse the drug slowly over 15 min
The nurse should infuse ondansetron slowly over 15 min to prevent chemotherapy-induced
nausea
E) Repeat the dose 4 hr after chemotherapy
For maximum effectiveness, the nurse should administer ondansetron 4 hr after chemotherapy,
and again 8 hr after chemotherapy. When treating anesthesia-induced nausea and vomiting the
nurse can give the drug 1 hr before anesthesia induction
A nurse is caring for a client who has a new prescription for alosetron to treat irritable bowel
syndrome. The nurse should instruct the client to report which of the following adverse effects
of the drug?
A) Headache
B) Drowsiness
,C)Abdominal Pain
D) Sore Throat - Answer C)Abdominal Pain
Alosetron, a serotonin 5-HT3 receptor antagonist, can cause ischemic colitis. The nurse should
tell the client to report abdominal pain, bloody diarrhea, or rectal bleeding, and stop taking the
drug if these manifestation occur.
A nurse is caring for an older adult client who has kidney disease and a new prescription for
cimetidine. The nurse should instruct the client to report which of the following manifestations?
A) Lethargy
B) Cellulitis
C) Dry mouth
D) Myalgia - Answer A) Lethargy
Cimetidine is a histamine2 receptor antagonist, which can potentially cross the blood-brain
barrier. Older adults who have kidney impairments are at risk for central nervous system (CNS)
effects such as lethargy, depression, confusion, and seizures. The nurse should instruct the
client to report these manifestations to their provider
Which of the following drugs has protocols that require clients to meet specific risk-
management criteria and sign a treatment agreement before the nurse can administer the
drug?
A) Lubiprostone
B) Azathioprine
C) Sulfasalazine
D) Alosetron - Answer D) Alosetron
Clients who take alosteron, a serotonin 5-HT3 receptor antagonist, can develop severe
constipation that can lead to impaction, bowel obstruction, perforation, and potentially fatal
ischemic colitis. Because of these risks, nurses must inform clients of the benefits and risks oft
eh drug therapy, and clients must sign a treatment agreement
A nurse is teaching a client who has a new prescription for methotrexate. The nurse should
instruct the client to monitor for manifestations of which of the following conditions?
A) Gout
B) Constipation
, C) Insomnia
D) Hursutism - Answer A) Gout
An adverse effect of methotrexate is hyperuricemia, which causes gout, The nurse should
instruct the client to drink plenty of fluids to minimize this effect, and to report edema or pain
the joints.
A nurse is teaching a client who has a new prescription for sulfasalazine. Which of the following
statements should the nurse make?
A) "Use sunscreen and protective clothing while taking sulfasalazine to prevent sunburn."
B) "The medication can stain your contact lenses green."
C) "The medication can color your urine dark brown"
D) "Take an iron supplement when you take sulfasalazine to prevent anemia" - Answer A)
"Use sunscreen and protective clothing while taking sulfasalazine to prevent sunburn."
Photosensitivity is a possible adverse effect of sulfasalazine that makes the skin sensitive to
light. The nurse should instruct the client to wear sunscreen and protective clothing when
outdoors to prevent burning
A nurse is teaching a client who recently had a myocardial infarction and has a new prescription
for docusate sodium. The nurse should inform the client that docusate sodium has which of the
following therapeutic effects?
A) Reduces inflammation
B) Reduces gastric acid
C) Prevent diarrhea
D) Prevents straining - Answer D) Prevents straining
Docusate sodium, a stool softener, prevents straining during defection and prevents the
elevation in blood pressure that can result from straining. It also helps relieve constipation and
reduces the painful elimination of hard stools
A nurse is caring for a client who has a new prescription for famotidine to treat GERD. The nurse
should instruct the client to wait at least 1 hr between taking famotidine and which of the
following over-the-counter drugs?
A) Ginkgo biloba
B) Antidiarrheals
