PHARMACOLOGY- NUR 3420 Exam 1
Test Questions Fully Solved 2025-2026
Updated.
Penicillins MOA - Answer Effects bacterial cell wall (bactericidal)
Penicillinase MOA - Answer Disrupt beta-lactam ring
Beta-lactamase Inhibitors - Answer Clavulanate, sulbactam, taxobactam
Aminopenicillins - Answer ampicillin broad spectrum
ampicillin-sulbactam
amoxicillin
amoxicillin-clavulanic acid
Anti-pseudomonals - Answer ticarcillin-clavulanate
Piperacillin-tazobactum
Penicillin side effects - Answer hypersensitivity, resistance, and GI distress
Cephalosporin MOA - Answer Disrupt cell wall synthesis (bactericidal)
Cephalosporin 1rst Generation - Answer cefazolin (Ancef, Kefzol) Gram positive
cephalexin (Keflex)
NO CSF
Cephalosporin 1rst Generation MOA - Answer Effective against gram positive and low activity
against gram negative
Cephalosporin 2nd Generation - Answer cefuroxime (Ceftin) Gram Negative
cefoxitin (Mefoxin)
cefaclor (Ceclor)
MINIMAL CSF
Cephalosporin 2nd Generation MOA - Answer Enhanced ability for gram negative bacteria
, Less effective on gram positive
Cephalosporin 3rd Generation - Answer cefdinir (Omnicef) Gram negative
cefotaxime (Claforan)
ceftazidime (Fortaz)
cefixime (Suprax)
ceftriaxone (Rocephin) (Eliminated in the liver)
PENETRATE CSF
Cephalosporin 3rd Generation MOA - Answer Some have activity against P.aeruginoisa
Highly active against gram-negative
Weak against gram positive. CAN penetrate CSF
Cephalosporin 4th Generation - Answer cefepime (Maxipime) Gram positive and negative
GOOD CSF ability
Cephalosporin 4th Generation MOA - Answer Pseudomonas Aeruginosa
Active against both gram-positive and gram-negative organisms
Cephalosporin 4th and 5th Generation - Answer ceftolozane-tazobactam (Zerbexa)
Cephalosporin 4th and 5th Generation MOA - Answer pseudomonas, specifically
Carbapenem-resistant pseudomonas
Cephalosporin side effects - Answer Hypersensitivity- allergic reaction
Nephrotoxicity (most are excreted by the kidneys)
Inhibit platelet function (monitor CBC)
Pseudo membranous colitis (caused by CDIF)
Neurotoxicity
Vancomycin MOA - Answer Inhibits cell wall synthesis and promotes bacterial lysis and death
Active only against gram positive
TREATS: C. diff, MRSA
Vancomycin Side Effects - Answer Nephrotoxicity
Test Questions Fully Solved 2025-2026
Updated.
Penicillins MOA - Answer Effects bacterial cell wall (bactericidal)
Penicillinase MOA - Answer Disrupt beta-lactam ring
Beta-lactamase Inhibitors - Answer Clavulanate, sulbactam, taxobactam
Aminopenicillins - Answer ampicillin broad spectrum
ampicillin-sulbactam
amoxicillin
amoxicillin-clavulanic acid
Anti-pseudomonals - Answer ticarcillin-clavulanate
Piperacillin-tazobactum
Penicillin side effects - Answer hypersensitivity, resistance, and GI distress
Cephalosporin MOA - Answer Disrupt cell wall synthesis (bactericidal)
Cephalosporin 1rst Generation - Answer cefazolin (Ancef, Kefzol) Gram positive
cephalexin (Keflex)
NO CSF
Cephalosporin 1rst Generation MOA - Answer Effective against gram positive and low activity
against gram negative
Cephalosporin 2nd Generation - Answer cefuroxime (Ceftin) Gram Negative
cefoxitin (Mefoxin)
cefaclor (Ceclor)
MINIMAL CSF
Cephalosporin 2nd Generation MOA - Answer Enhanced ability for gram negative bacteria
, Less effective on gram positive
Cephalosporin 3rd Generation - Answer cefdinir (Omnicef) Gram negative
cefotaxime (Claforan)
ceftazidime (Fortaz)
cefixime (Suprax)
ceftriaxone (Rocephin) (Eliminated in the liver)
PENETRATE CSF
Cephalosporin 3rd Generation MOA - Answer Some have activity against P.aeruginoisa
Highly active against gram-negative
Weak against gram positive. CAN penetrate CSF
Cephalosporin 4th Generation - Answer cefepime (Maxipime) Gram positive and negative
GOOD CSF ability
Cephalosporin 4th Generation MOA - Answer Pseudomonas Aeruginosa
Active against both gram-positive and gram-negative organisms
Cephalosporin 4th and 5th Generation - Answer ceftolozane-tazobactam (Zerbexa)
Cephalosporin 4th and 5th Generation MOA - Answer pseudomonas, specifically
Carbapenem-resistant pseudomonas
Cephalosporin side effects - Answer Hypersensitivity- allergic reaction
Nephrotoxicity (most are excreted by the kidneys)
Inhibit platelet function (monitor CBC)
Pseudo membranous colitis (caused by CDIF)
Neurotoxicity
Vancomycin MOA - Answer Inhibits cell wall synthesis and promotes bacterial lysis and death
Active only against gram positive
TREATS: C. diff, MRSA
Vancomycin Side Effects - Answer Nephrotoxicity
