ABOG Reproductive Endocrinology & Infertility
(REI) Certification Fundamentals Practice EXAM
QUESTIONS AND CORRECT ANSWERS (VERIFIED
ANSWERS) Q&A 2026|INSTANT DOWNLOAD PDF
1. Which hormone primarily stimulates follicular development
in the ovary?
A. LH
B. FSH
C. Progesterone
D. Prolactin
Rationale: FSH promotes granulosa cell proliferation and follicle
growth.
Correct Answer: B
2. The two-cell, two-gonadotropin theory explains estrogen
synthesis involving which cells?
A. Granulosa only
B. Theca only
C. Theca and granulosa
D. Stromal cells
Rationale: Theca cells produce androgens; granulosa cells
aromatize them to estrogen.
Correct Answer: C
3. Which hormone surge triggers ovulation?
A. FSH
B. Estrogen
,C. Progesterone
D. LH
Rationale: The LH surge induces follicular rupture.
Correct Answer: D
4. Anti-Müllerian hormone (AMH) is secreted by which cells?
A. Theca cells
B. Granulosa cells of small follicles
C. Luteal cells
D. Oocytes
Rationale: AMH reflects ovarian reserve via small antral
follicles.
Correct Answer: B
5. A normal mid-luteal progesterone level indicates:
A. Adequate ovulation
B. Follicular phase
C. Menstrual phase
D. Ovarian failure
Rationale: Progesterone rises after ovulation.
Correct Answer: A
6. Which structure secretes progesterone after ovulation?
A. Follicle
B. Corpus albicans
C. Corpus luteum
D. Endometrium
Rationale: Corpus luteum forms post-ovulation.
Correct Answer: C
, 7. Primary infertility is defined as failure to conceive after:
A. 6 months
B. 12 months
C. 18 months
D. 24 months
Rationale: Standard definition is 12 months of unprotected
intercourse.
Correct Answer: B
8. Secondary infertility refers to:
A. Infertility in nulliparous women
B. Infertility after prior conception
C. Male factor infertility
D. Tubal factor only
Rationale: Secondary follows at least one prior pregnancy.
Correct Answer: B
9. Most common cause of female infertility worldwide:
A. Endometriosis
B. Ovulatory dysfunction
C. Tubal disease
D. Uterine anomalies
Rationale: Ovulatory disorders are most common overall.
Correct Answer: B
10. PCOS diagnostic criteria (Rotterdam) require two of the
following except:
A. Hyperandrogenism
B. Polycystic ovaries
(REI) Certification Fundamentals Practice EXAM
QUESTIONS AND CORRECT ANSWERS (VERIFIED
ANSWERS) Q&A 2026|INSTANT DOWNLOAD PDF
1. Which hormone primarily stimulates follicular development
in the ovary?
A. LH
B. FSH
C. Progesterone
D. Prolactin
Rationale: FSH promotes granulosa cell proliferation and follicle
growth.
Correct Answer: B
2. The two-cell, two-gonadotropin theory explains estrogen
synthesis involving which cells?
A. Granulosa only
B. Theca only
C. Theca and granulosa
D. Stromal cells
Rationale: Theca cells produce androgens; granulosa cells
aromatize them to estrogen.
Correct Answer: C
3. Which hormone surge triggers ovulation?
A. FSH
B. Estrogen
,C. Progesterone
D. LH
Rationale: The LH surge induces follicular rupture.
Correct Answer: D
4. Anti-Müllerian hormone (AMH) is secreted by which cells?
A. Theca cells
B. Granulosa cells of small follicles
C. Luteal cells
D. Oocytes
Rationale: AMH reflects ovarian reserve via small antral
follicles.
Correct Answer: B
5. A normal mid-luteal progesterone level indicates:
A. Adequate ovulation
B. Follicular phase
C. Menstrual phase
D. Ovarian failure
Rationale: Progesterone rises after ovulation.
Correct Answer: A
6. Which structure secretes progesterone after ovulation?
A. Follicle
B. Corpus albicans
C. Corpus luteum
D. Endometrium
Rationale: Corpus luteum forms post-ovulation.
Correct Answer: C
, 7. Primary infertility is defined as failure to conceive after:
A. 6 months
B. 12 months
C. 18 months
D. 24 months
Rationale: Standard definition is 12 months of unprotected
intercourse.
Correct Answer: B
8. Secondary infertility refers to:
A. Infertility in nulliparous women
B. Infertility after prior conception
C. Male factor infertility
D. Tubal factor only
Rationale: Secondary follows at least one prior pregnancy.
Correct Answer: B
9. Most common cause of female infertility worldwide:
A. Endometriosis
B. Ovulatory dysfunction
C. Tubal disease
D. Uterine anomalies
Rationale: Ovulatory disorders are most common overall.
Correct Answer: B
10. PCOS diagnostic criteria (Rotterdam) require two of the
following except:
A. Hyperandrogenism
B. Polycystic ovaries
