TEST BANK
Basic and Clinical Pharmacology
BY BERTRAM KATZUNG
14th Edition
, Test bank for Basic and Clinical Pharmacology 14th Edition by Katzung
Basic and Clinical Pharmacology 14th Edition Katzung Trevor
Test Bank
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
1. A nurse working in radiology administers iodine to a patient who is
having a computed tomography (CT) scan. The nurse working on
the oncology unit administers chemotherapy to patients who have
cancer. At the Public Health Department, a nurse administers a
measles-mumps-rubella (MMR) vaccine to a 14-month-old child as
a routine immunization. Which branch of pharmacology best
describes the actions of all three nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals.
Nurses are involved with clinical pharmacology or
pharmacotherapeutics, which is a branch of pharmacology that
deals with the uses of drugs to treat, prevent, and diagnose
disease. The radiology nurse is administering a drug to help
diagnose a disease. The oncology nurse is administe1ing a drug to
help treat a disease. Pharmacoeconomics includes any costs
involved in drug therapy.
Pharmacodynamics involves how a drug affects the body and
pharmacokinetics is how the body acts on the body.
2. A physician has ordered intramuscular (IM) injections of
morphine, a narcotic, every 4 hours as needed for pain in a motor
vehicle accident victim. The nurse is aware this drug has a high
abuse potential. Under what category would morphine be
classified?
A) Schedule I
B) Schedule II
, Test bank for Basic and Clinical Pharmacology 14th Edition by Katzung
C) Schedule III
D) Schedule IV
Ans: B
Feedback:
Narcotics with a high abuse potential are classified as Schedule II
drugs because of severe dependence liability. Schedule I drugs
have high abuse potential and no accepted medical use. Schedule
III drugs have a lesser abuse potential than II and an accepted
medical use. Schedule IV drugs have low abuse potential and
limited dependence liability.
3. When involved in phase III drug evaluation studies, what
responsibilities would the nurse have?
A) Working with animals who are given experimental drugs
B) Choosing appropriate patients to be involved in the drug study
C) Monitoring and observing patients closely for adverse effects
D) Conducting research to determine effectiveness of
the drug Ans: C
Feedback:
Phase III studies involve use of a drug in a vast clinical population
in which patients are asked to record any symptoms they
experience while taking the drugs. Nurses may be responsible for
helping collect and analyze the information to be shared with the
Food and Drug Administration (FDA) but would not conduct
research independently because nurses do not prescribe
medications. Use of animals in drug testing is done in the
preclinical trials. Select patients who are involved in phase II
studies to participate in studies where the participants have the
disease the drug is intended to treat. These patients are
monitored closely for drug action and adverse effects. Phase I
studies involve healthy human volunteers who are usually paid for
their participation. Nurses may observe for adverse effects and
toxicity.
4. What concept is considered when generic drugs are substituted
for brand name drugs?
A) Bioavailability
, Test bank for Basic and Clinical Pharmacology 14th Edition by Katzung
B) Ctitical concentration
C) Distribution
D) Half-life
Ans: A
Feedback:
Bioavailability is the portion of a dose of a drug that reaches the
systemic circulation and is available to act on body cells. Binders
used in a generic drug may not be the same as those used in the
brand name drug. Therefore, the way the body breaks down and
uses the drug may differ, which may eliminate a generic drug
substitution. Critical concentration is the amount of a drug that is
needed to cause a therapeutic effect and should not differ
between generic and brand name medications. Distribution is the
phase of pharmacokinetics, which involves the movement of a
drug to the bodys tissues and is the same in generic and brand
name drugs. A drugs half-life is the time it takes for the amount of
drug to decrease to half the peak level, which should not change
when substituting a generic medication.
5. A nurse is assessing the patients home medication use. After
listening to the patient list current medications, the nurse asks
what priority question?
A) Do you take any generic medications?
B) Are any of these medications orphan drugs?
C) Are these medications safe to take during pregnancy?
D) Do you take any over-the-counter medications?
Ans: D
Feedback:
It is important for the nurse to specifically question use of over-
the-counter medications because patients may not consider them
important. The patient is unlikely to know the meaning of orphan
drugs unless they too are health care providers. Safety during
pregnancy, use of a generic medication, or classification of orphan
drugs are things the patient would be unable to answer but could
be found in reference books if the nurse wishes to research them.
Basic and Clinical Pharmacology
BY BERTRAM KATZUNG
14th Edition
, Test bank for Basic and Clinical Pharmacology 14th Edition by Katzung
Basic and Clinical Pharmacology 14th Edition Katzung Trevor
Test Bank
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
1. A nurse working in radiology administers iodine to a patient who is
having a computed tomography (CT) scan. The nurse working on
the oncology unit administers chemotherapy to patients who have
cancer. At the Public Health Department, a nurse administers a
measles-mumps-rubella (MMR) vaccine to a 14-month-old child as
a routine immunization. Which branch of pharmacology best
describes the actions of all three nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals.
Nurses are involved with clinical pharmacology or
pharmacotherapeutics, which is a branch of pharmacology that
deals with the uses of drugs to treat, prevent, and diagnose
disease. The radiology nurse is administering a drug to help
diagnose a disease. The oncology nurse is administe1ing a drug to
help treat a disease. Pharmacoeconomics includes any costs
involved in drug therapy.
Pharmacodynamics involves how a drug affects the body and
pharmacokinetics is how the body acts on the body.
2. A physician has ordered intramuscular (IM) injections of
morphine, a narcotic, every 4 hours as needed for pain in a motor
vehicle accident victim. The nurse is aware this drug has a high
abuse potential. Under what category would morphine be
classified?
A) Schedule I
B) Schedule II
, Test bank for Basic and Clinical Pharmacology 14th Edition by Katzung
C) Schedule III
D) Schedule IV
Ans: B
Feedback:
Narcotics with a high abuse potential are classified as Schedule II
drugs because of severe dependence liability. Schedule I drugs
have high abuse potential and no accepted medical use. Schedule
III drugs have a lesser abuse potential than II and an accepted
medical use. Schedule IV drugs have low abuse potential and
limited dependence liability.
3. When involved in phase III drug evaluation studies, what
responsibilities would the nurse have?
A) Working with animals who are given experimental drugs
B) Choosing appropriate patients to be involved in the drug study
C) Monitoring and observing patients closely for adverse effects
D) Conducting research to determine effectiveness of
the drug Ans: C
Feedback:
Phase III studies involve use of a drug in a vast clinical population
in which patients are asked to record any symptoms they
experience while taking the drugs. Nurses may be responsible for
helping collect and analyze the information to be shared with the
Food and Drug Administration (FDA) but would not conduct
research independently because nurses do not prescribe
medications. Use of animals in drug testing is done in the
preclinical trials. Select patients who are involved in phase II
studies to participate in studies where the participants have the
disease the drug is intended to treat. These patients are
monitored closely for drug action and adverse effects. Phase I
studies involve healthy human volunteers who are usually paid for
their participation. Nurses may observe for adverse effects and
toxicity.
4. What concept is considered when generic drugs are substituted
for brand name drugs?
A) Bioavailability
, Test bank for Basic and Clinical Pharmacology 14th Edition by Katzung
B) Ctitical concentration
C) Distribution
D) Half-life
Ans: A
Feedback:
Bioavailability is the portion of a dose of a drug that reaches the
systemic circulation and is available to act on body cells. Binders
used in a generic drug may not be the same as those used in the
brand name drug. Therefore, the way the body breaks down and
uses the drug may differ, which may eliminate a generic drug
substitution. Critical concentration is the amount of a drug that is
needed to cause a therapeutic effect and should not differ
between generic and brand name medications. Distribution is the
phase of pharmacokinetics, which involves the movement of a
drug to the bodys tissues and is the same in generic and brand
name drugs. A drugs half-life is the time it takes for the amount of
drug to decrease to half the peak level, which should not change
when substituting a generic medication.
5. A nurse is assessing the patients home medication use. After
listening to the patient list current medications, the nurse asks
what priority question?
A) Do you take any generic medications?
B) Are any of these medications orphan drugs?
C) Are these medications safe to take during pregnancy?
D) Do you take any over-the-counter medications?
Ans: D
Feedback:
It is important for the nurse to specifically question use of over-
the-counter medications because patients may not consider them
important. The patient is unlikely to know the meaning of orphan
drugs unless they too are health care providers. Safety during
pregnancy, use of a generic medication, or classification of orphan
drugs are things the patient would be unable to answer but could
be found in reference books if the nurse wishes to research them.
