Correct Answers || ||
the endocrine system is dependent on
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negative feedback systems || ||
negative feedback system || ||
A reaction that causes a decrease in function in response
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to some kind of stimulus.
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negative feedback system: example 1|| || || ||
a HIGH blood level of a circulating hormone (a hormone is
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basically a chemicalmessenger) will
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automaticallysuppress the gland that secreted it and/or || || || || || || ||
otherglands in the feedback loop, thusdecreasing || || || || || ||
secretion of that hormone || || ||
negative feedback system: example 2|| || || ||
a LOW blood level of a circulating hormone will
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automatically stimulate the glandthat secreted it and/or || || || || || || ||
,other glands in the feedback loop.. the result is that
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therewill be MORE of the hormone in circulation
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pituitary gland ||
AKA hypophysis AKA master gland located in brain near
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base of skull|| ||
pituitary gland secretes || ||
1. antidiuretic hormone (ADH)
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2. thyroid-stimulating hormone (TSH)
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3. adrenocorticotropic hormone (ACTH)
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ADH normally released when..
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process that the body uses tocompensate for ("fix") low
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fluid volume: when the pituitary detects that circulating
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fluid volume is low, (the body has a high osmolality or
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high blood concentration) it secretes ADH > ADH "tells"
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kidneys to "hang onto" water by decreasing urine output
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> fluids are conserved and fluid volume in the body goes
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up.
,normal ADH process:
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low volume/high osmolality alerts pituitary > ADH
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released from the pituitary > ADH tells kidney to hang on
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to water > ADH released from pituitary > kidneys sense
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low fluid volume, low BP, and high blood concentration >
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kidneys secrete renin (RAAS activated) > angiotensin I >
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angiotensin II > peripheral vasoconstriction and || || || || || ||
aldosterone release from adrenal gland || || || ||
diabetes insipidus (DI) (ADH problem)
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undersecretion; means “to pass too much urine;” || || || || || || ||
insipidus means “flavorless” (refers to the fact that the
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urine has no color because it is very dilute)
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two causes for diabetes insipidus (DI)
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renal or CNS problems
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, renal problems (diabetes insipidus)
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"sick" kidneys often have adecreased response of renal
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tubules to ADH || ||
CNS problems (diabetes insipidus)
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1. a lesion such as a pituitary tumor causes the gland
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todiminishits secretion of ADH || || ||
2. acute abnormality in the brain such as head injury
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orother causes of cerebral edema & IICP in the brain
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canput pressure on the pituitary gland & cause it
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todiminish ADH secretion || ||
decrease in ADH due to ____ whereas increase in ADH due
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to ____
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diabetes insipidus; SIADH || ||
decrease in ADH = || || ||
kidneys will allow more H2O in urine (polyuria) > increase
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in UO > decrease in H2O in body > increase in osmolality
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