Detailed Answers
1. Isosorbide dinitrate (Isordil) is prescribed for a patient with chronic stable
angina. This drug is administered twice a daily, but the schedule is 7 AM
and 2 PM because:
Group of answer choices
It is a long- acting drug with potential for toxicity
It must be taken with milk or food
Orthostatic hypotension is a common adverse effect
Nitrate tolerance can develop - ANSWER Nitrate tolerance can develop
2. Charlie is a 65 year old male who has been diagnosed with hypertension and
benign prostatic hyperplasia. Cardura (doxazosin) has been chosen to treat
his hypertension because it also:
Increases peripheral vasoconstriction
Decreases detrusor muscle contractility
Relaxes smooth muscle in the bladder neck - ANSWER relaxes smooth muscle
in the bladder neck
3. Which of the following statements is true regarding the choice of diuretic to
use in treating hypertension:
If diabetes is a comorbid condition, a loop diuretic should be used
A thiazide diuretic should be used for patient with an estimated glomerular
filtration rate higher than the mid-40 mL/min range
Aldosterone antagonists are best for African Americans and older adults
,Higher doses are needed for patients with a presence of hyperlipidemia and an
LDL above 130 mg/dL - ANSWER A thiazide diuretic should be used for
patient with an estimated glomerular filtration rate higher than the mid-40
mL/min range
4. Isosorbide dinitrate (Isordil) is prescribed for a patient with chronic stable
angina. This drug is administered twice a daily, but the schedule is 7 AM
and 2 PM because:
It is a long- acting drug with potential for toxicity
Nitrate tolerance can develop
Orthostatic hypotension is a common adverse effect
It must be taken with milk or food - ANSWER Nitrate tolerance can develop
5. Which of the following is true regarding loop diuretics?
They are short acting and produce substantial initial diuresis
They inhibit sodium reabsorption at the distal renal tubule
They are potassium sparing
Due to their weak effect, they are best combined with thiazide type diuretics -
ANSWER they are short acting and produce substantial initial diuresis
6. Laboratory monitoring for patients on ACEIs or ARBs should include:
White blood cells counts with drug dose increased for elevations above 10,000
Liver function tests with the drug dose stopped for ALT values 2 normal
Serum creatinine levels with the drug dose reduced for value above 2.5 mg/dL
Serum glucose levels with the drug dose increased for levels above 120 mg/dL -
ANSWER Serum creatinine levels with the drug dose reduced for value above
2.5 mg/dL
, 7. Hannah will be traveling to Mexico with her church group over Spring
Break to build houses. She is concerned she may develop traveler's diarrhea.
Advice includes normal food and water precautions as well as:
Group of answer choices
None of the above
A prescription for diphenoxylate with atropine (Lomotil) to use if she gets
diarrhea
Loperamide (Imodium) four times a day throughout the trip
Bismuth subsalicylate (Pepto-Bismol) with each meal and bedtime - ANSWER
Bismuth subsalicylate (Pepto-Bismol) with each meal and bedtime
8. PPIs should be taken with food.
Group of answer choices
True
False - ANSWER false
9. Because of their site of action, bile acid sequestering resins: - ANSWER
Should be administered separate from other drugs by several hours
10.Which medication is most effective at increasing HDL cholesterol? -
ANSWER niacin
11.Lamotrigine (Lamictal) has a black box warning stating that patients should
watch for the development of______.
Congestive heart failure
Life-threatening rashes
Photosensitivity
Anaphylaxis - ANSWER Life-threatening rashes