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NR 566 Midterm Study Guide: Advanced Pharmacology Review – Antibiotics, Weight Loss, Antivirals, & Reproductive Health (Complete Questions & Answers)

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Excel in your NR 566 Midterm with this comprehensive study guide and test bank. This resource provides high-yield practice questions and detailed answers covering the core pillars of advanced pharmacology, including antimicrobial therapy, obesity management, and clinical therapeutics for reproductive health. Key Subject Areas Covered: • Antibiotic Stewardship & Clinical Use: In-depth review of Penicillins, Cephalosporins (and cross-sensitivity), Tetracyclines (contraindications in pregnancy/children), Macrolides (QT prolongation risks), and Aminoglycosides (ototoxicity and nephrotoxicity monitoring). • Obesity & Weight Loss Management: Clinical guidelines for BMI classification and pharmacological interventions including Phentermine/Topiramate (Qsymia), Orlistat (fat-soluble vitamin supplementation), Contrave (naltrexone/bupropion suicide risk), and Liraglutide (Saxenda). • Antiviral & HIV Therapeutics: Management of HSV/VZV with Acyclovir, influenza treatment windows for Oseltamivir, and complex HIV regimens involving NRTIs, NNRTIs, and Protease Inhibitors (monitoring for lactic acidosis and PR interval changes). • Women’s & Men’s Health: Guidelines for Hormone Replacement Therapy (HRT), oral contraceptives (clotting risks and drug interactions), Testosterone therapy (monitoring for virilization and erythropoiesis), and Erectile Dysfunction/BPH treatments like Sildenafil and Finasteride. • STI & Helminthic Infections: First-line treatments for Chlamydia, Gonorrhea, and Syphilis, as well as safety profiles for Anthelmintics like Albendazole and Praziquantel. • Dermatology, Eyes, & Ears: Clinical pearls for acne (Isotretinoin/Benzoyl Peroxide), Otitis Media vs. Externa, and glaucoma treatments such as Latanoprost. This guide emphasizes baseline data collection, patient education, and Black Box Warnings, making it an essential resource for NP students preparing for midterm exams and clinical practice.

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NR 566 Midterm Study Guide | Complete
Pharmacology Review | Antibiotics, Weight Loss,
Antivirals.




Taking Itraconazole with _______ will help enhance absorption
A) Cola
B) Greek yogurt
C) Vitamin C
D) Alcohol - ANSWER-COLA

Which pathogen is highly associated with CAP in the general
population?
A)Haemophilus influenza
B)Pseudomonas Aeruginosa
C)Streptococcus pneumonia
D)None of these are correct - ANSWER-C)Streptococcus pneumonia

Why might a patient being treated with Contrave for obesity not have
therapeutic effects from hydrocodone after dental procedure?
A) It contains bupropion which will interact with hydrocodone
B) Hydrocodone isn't for pain
C) He hasn't been taking the prescribed dose
D) Contrave contains naltrexone - ANSWER-D) Contrave contains
naltrexone

What is the unique adverse effect that Latanoprost can cause?
A) Heart block and bradycardia
B) Heightened brown pigmentation of the iris and eyelid
C) Headache, dry mouth, dry nose, and altered taste

,2|Page


D) Miosis and blurred vision - ANSWER-B) Heightened brown
pigmentation of the iris and eyelid

What is the first line antibiotic for infection caused by animal/human
bites?
A) Amoxicillin
B) Amoxicillin/Clavulanate
C) Cephalexin
D) Clarithromycin - ANSWER-B) Amoxicillin/Clavulanate

Which of the following medications can treat infections of the eyes
AND ears
A) Neomycin
B) Debrox
C) Gentamicin
D) Tobramycin - ANSWER-A) Neomycin

This antibiotic class can be used to treat infection in infants younger
than 8 days old.
A) Cephalosporins
B) Aminoglycosides
C) Macrolides
D) Sulfonamides - ANSWER-B) Aminoglycosides

This antibiotic is used to treat uncomplicated UTIs
A) Vancomycin
B) Flagyl
C) Tetracyclines
D) Sulfamethoxazole/Trimethoprim - ANSWER-D)
Sulfamethoxazole/Trimethoprim

Which antibiotic is NOT recommended for UTIs of the upper urinary
tract?
A) Nitrofurantoin
B) Ampicillin

,3|Page


C) Azithromycin
D) Sulfamethoxazole/Trimethoprim - ANSWER-A) Nitrofurantoin

This pathogen is highly associated with CAP in smokers and those with
COPD
A) Haemophilus influenza (gram +)
B) Streptococcus pneumonia (gram +)
C) Haemophilus influenza (gram -)
D) Streptococcus (gram -) - ANSWER-C) Haemophilus influenza (gram
-)

What is the therapeutic action of Guaifenesin?
A) Expectorant
B) H1 blockers
C) Cough suppressant
D) Mucolytic - ANSWER-A) Expectorant

What compound must be present in organic sunscreen for it to be
effective?
A) Titanium dioxide
B) Zinc oxide
C) Avobenzone
D) Albendazole - ANSWER-C) Avobenzone

What is first-line treatment for severe acne?
A) Doxycycline and Isotretinoin
B) Retinoids
C) Penicillin and cephalosporins
D) Salicyclic acid
E) Both A&B - ANSWER-E) Both A&B

What is first-line treatment for mild acne?
A) Oral antibiotics (e.g., doxycycline, minocycline) and comedolytics
B) Benzyl peroxide
C) Diferin

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D) Oral contraceptives (Ocs) and spironolactone - ANSWER-B) Benzyl
peroxide

What patient education is needed for Isotretinoin?
A) Protect skin from sunlight and avoid sunlamps and tanning beds
B) Pregnancy should be avoided, and two reliable birth-control methods
used
C) Risk for depression and suicide
D) All options are correct
E) A & B only - ANSWER-D) All options are correct

What is the most effective drugs for prevention and treatment of
seasonal and perennial rhinitis?
A) Sympathomimetics
B) Intranasal glucocorticoids
C) Oral steroids
D) Diphenhydramine - ANSWER-B) Intranasal glucocorticoids

Type 2 DM, Gallbladder Disease, Fatty Liver Disease, and Gout are a
few possible complications of __________.
A) Someone with a BMI between 30-40
B) BKAs from Type 2 DM
C) Anyone over the age of 65 with renal disease
D) Long term use of glucocorticoids - ANSWER-A) Someone with a
BMI between 30-40

The new NP knows that which weight loss drug could causes
hypothyroidism in a patient taking levothyroxine.
A) Phentermine
B) Orlistat
C) Contrave
D) Topamax - ANSWER-B) Orlistat

Contrave is a combination of which two medications?
A) Orlistat and naltrexone

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