ACNPC-AG Practice Examination Review with Answers
and Rationales | 100% Pass Guaranteed | Graded A+
1. A 68-year-old with COPD presents with increased dyspnea and
purulent sputum. Which is the most appropriate initial
antibiotic choice?
A. Azithromycin
B. Amoxicillin-clavulanate
C. Doxycycline
D. Ceftriaxone
* * Doxycycline covers common pathogens and is appropriate
for outpatient management of COPD exacerbations in many
cases. * *
2. In sepsis, the most important initial intervention is:
A. Broad-spectrum antibiotics
B. Fluid resuscitation
C. Vasopressor therapy
D. Steroids
* * Restoring intravascular volume improves perfusion and is
first priority in septic shock. * *
3. Which lab result is most indicative of DIC?
A. Elevated ESR
B. Elevated fibrinogen
C. Elevated D-dimer
D. Low PT
* * D-dimer rises in the presence of fibrinolysis, a hallmark of
DIC. * *
4. A 45-year-old with suspected MI should first receive:
A. Beta-blocker
B. Aspirin
C. Nitroglycerin
D. Morphine
, * * Aspirin reduces mortality by inhibiting platelet aggregation
early. * *
5. The best test to distinguish ischemic from hemorrhagic stroke
is:
A. EEG
B. Carotid Doppler
C. CT head without contrast
D. MRI
* * Non-contrast CT quickly identifies hemorrhage in acute
stroke. * *
Pharmacology & Therapeutics
6. What is the antidote for acetaminophen toxicity?
A. Naloxone
B. Flumazenil
C. N-acetylcysteine
D. Vitamin K
* * N-acetylcysteine replenishes glutathione to prevent liver
injury. * *
7. Which medication is first-line for status epilepticus?
A. Phenytoin
B. Valproate
C. Lorazepam
D. Levetiracetam
* * Benzodiazepines rapidly terminate seizures and are first
choice. * *
8. A critically ill patient develops torsades de pointes. The best
treatment is:
A. Amiodarone
B. Lidocaine
, C. Magnesium sulfate
D. Calcium chloride
* * Magnesium stabilizes cardiac membranes in torsades. * *
9. For acute pulmonary edema with hypertension, you should
give:
A. Beta-blocker
B. Nitroglycerin
C. Antibiotics
D. Steroids
* * Nitroglycerin reduces preload and afterload, improving
symptoms. * *
10. Which anticoagulant requires antithrombin III for
activity?
A. Warfarin
B. Heparin
C. Dabigatran
D. Rivaroxaban
* * Heparin potentiates antithrombin III to inhibit clotting
factors. * *
Advanced Assessment & Diagnostics
11. A patient with CHF has an S3 heart sound. This suggests:
A. Pericardial effusion
B. Aortic stenosis
C. Volume overload
D. Pulmonary hypertension
* * S3 is associated with increased filling pressures in CHF. * *
12. Which ECG change suggests myocardial ischemia?
A. Elevated U waves
B. ST depression
and Rationales | 100% Pass Guaranteed | Graded A+
1. A 68-year-old with COPD presents with increased dyspnea and
purulent sputum. Which is the most appropriate initial
antibiotic choice?
A. Azithromycin
B. Amoxicillin-clavulanate
C. Doxycycline
D. Ceftriaxone
* * Doxycycline covers common pathogens and is appropriate
for outpatient management of COPD exacerbations in many
cases. * *
2. In sepsis, the most important initial intervention is:
A. Broad-spectrum antibiotics
B. Fluid resuscitation
C. Vasopressor therapy
D. Steroids
* * Restoring intravascular volume improves perfusion and is
first priority in septic shock. * *
3. Which lab result is most indicative of DIC?
A. Elevated ESR
B. Elevated fibrinogen
C. Elevated D-dimer
D. Low PT
* * D-dimer rises in the presence of fibrinolysis, a hallmark of
DIC. * *
4. A 45-year-old with suspected MI should first receive:
A. Beta-blocker
B. Aspirin
C. Nitroglycerin
D. Morphine
, * * Aspirin reduces mortality by inhibiting platelet aggregation
early. * *
5. The best test to distinguish ischemic from hemorrhagic stroke
is:
A. EEG
B. Carotid Doppler
C. CT head without contrast
D. MRI
* * Non-contrast CT quickly identifies hemorrhage in acute
stroke. * *
Pharmacology & Therapeutics
6. What is the antidote for acetaminophen toxicity?
A. Naloxone
B. Flumazenil
C. N-acetylcysteine
D. Vitamin K
* * N-acetylcysteine replenishes glutathione to prevent liver
injury. * *
7. Which medication is first-line for status epilepticus?
A. Phenytoin
B. Valproate
C. Lorazepam
D. Levetiracetam
* * Benzodiazepines rapidly terminate seizures and are first
choice. * *
8. A critically ill patient develops torsades de pointes. The best
treatment is:
A. Amiodarone
B. Lidocaine
, C. Magnesium sulfate
D. Calcium chloride
* * Magnesium stabilizes cardiac membranes in torsades. * *
9. For acute pulmonary edema with hypertension, you should
give:
A. Beta-blocker
B. Nitroglycerin
C. Antibiotics
D. Steroids
* * Nitroglycerin reduces preload and afterload, improving
symptoms. * *
10. Which anticoagulant requires antithrombin III for
activity?
A. Warfarin
B. Heparin
C. Dabigatran
D. Rivaroxaban
* * Heparin potentiates antithrombin III to inhibit clotting
factors. * *
Advanced Assessment & Diagnostics
11. A patient with CHF has an S3 heart sound. This suggests:
A. Pericardial effusion
B. Aortic stenosis
C. Volume overload
D. Pulmonary hypertension
* * S3 is associated with increased filling pressures in CHF. * *
12. Which ECG change suggests myocardial ischemia?
A. Elevated U waves
B. ST depression
