PHARMACOLOGY 9TH EDITION BY AMY
KARCH CHAPTER 1-59 ISBN 13;978-
1975180409/ISBN 10;1975180402 COMPLETE
GUIDE/ GRADED A+
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Chapter 01- Introduction to Drugs
A nurse working in radiology administers iodine to a patient who is having a
computed tomography(CT) scan. The nurse working on the oncology unit
administers chemotherapy to patients who have cancer. At the Public Health
Department, a nurse administers a measles-mumps-rubella (MMR) vaccine to a
14-month-old child as a routine immunization. Which branch of pharmacology
best describes the actions of all three nurses?
Pharmacoeconomics
Pharmacotherapeutics
Pharmacodynamics
Pharmacokinetics
Ans: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are
involved with clinical pharmacology or pharmacotherapeutics, which is a branch of
pharmacology that deals with the uses of drugs to treat, prevent, and diagnose
disease. The radiology nurse is administering a drug to help diagnose a disease.
The oncology nurse is administering a drug to help treat a disease.
Pharmacoeconomics includes any costs involved in drug therapy. Pharmacodynamics
involves how a drug affects the body and pharmacokinetics is how the body
acts on the body.
A physician has ordered intramuscular (IM) injections of morphine, a narcotic, every 4
hours as neededfor pain in a motor vehicle accident victim. The nurse is
aware this drug has a high abuse potential. Under what category would
morphine be classified?
Schedule I
Schedule II
Schedule
III
Schedule
IV Ans: B
Feedback:
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Narcotics with a high abuse potential are classified as Schedule II drugs because
of severe dependence
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liability. Schedule I drugs have high abuse potential and no accepted medical use.
Schedule III drugs have a lesser abuse potential than II and an accepted medical
use. Schedule IV drugs have low abuse potential and limited dependence liability.
When involved in phase III drug evaluation studies, what responsibilities would
the nurse have? Working with animals who are given experimental drugs
Choosing appropriate patients to be involved in the
drug study Monitoring and observing patients closely
for adverse effects Conducting research to determine
effectiveness of the drugAns: C
Feedback:
Phase III studies involve use of a drug in a vast clinical population in which
patients are asked to record any symptoms they experience while taking the
drugs. Nurses may be responsible for helping collect and analyze the information
to be shared with the Food and Drug Administration (FDA) but would not conduct
research independently because nurses do not prescribe medications. Use of
animals in drug testing is done in the preclinical trials. Select patients who are
involved in phase II studies to participate in studies where the participants
have the disease the drug is intended to treat. These patients are monitored
closely for drug action and adverse effects. Phase I studies involve healthy human
volunteers who are usually paid for their participation. Nurses may observe for
adverse effects and toxicity.
What concept is considered when generic drugs are substituted for brand name
drugs? Bioavailability
Critical
concentration
Distribution
Half-life
Ans: A
Feedback:
Bioavailability is the portion of a dose of a drug that reaches the systemic
circulation and is available to act on body cells. Binders used in a generic drug
may not be the same as those used in the brand name drug. Therefore, the way