1 | Page
1. Chamberlain University-Illinois
2. NR 222
Pathophysiology Exam 1 Questions and
Answers 2026 Latest
An ordered photographic display of a set of chromosomes from a single cell
is a(n):
A) metaphase spread.
B) autosomal spread.
C) karyotype.
D) anaphase spread. Ans: c
An error in which homologous chromosomes fail to separate during meiosis
is termed:
A) aneuploidy.
B) nondisjunction.
C) polyploidy.
D) anaplasia. Ans: b
A somatic cell that does not contain a multiple of 23 chromosomes is called:
A) an aneuploid cell.
B) a euploid cell.
C) a polyploidy cell.
D) a haploid cell. Ans: a
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, 2 | Page
A 20-year-old pregnant female gives birth to a stillborn child. Autopsy
reveals that the fetus has 92 chromosomes. Which of the following
describes this condition?
A) Euploidy
B) Triploidy
C) Tetraploidy
D) Aneuploidy Ans: c
If a person is a chromosomal mosaic, the person may:
A) be a carrier of the genetic disease.
B) have a mild form of the genetic disease.
C) have two genetic diseases.
D) be sterile as a result of the genetic disease. Ans: b
The most common cause of Down syndrome is:
A) paternal nondisjunction.
B) maternal translocations.
C) maternal nondisjunction.
D) paternal translocations. Ans: c
Risk factors for Down syndrome include:
A) fetal exposure to mutagens in the uterus.
B) increased paternal age.
C) family history of Down syndrome.
D) pregnancy in women over age 35. Ans: d
A 13-year-old girl has a karyotype that reveals an absent homologous X
chromosome with only a single X chromosome present. Her condition is
called:
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, 3 | Page
A) Down syndrome.
B) Cri du chat syndrome.
C) Turner syndrome.
D) Edward syndrome Ans: c
A child is diagnosed with cystic fibrosis. History reveals that the child's
parents are first cousins. Cystic fibrosis was most likely the result of:
A) X inactivation.
B) genomic imprinting.
C) consanguinity.
D) obligate carriers. Ans: c
Joey, age 9, is admitted to a pediatric unit with Duchenne muscular
dystrophy. He inherited this condition through a:
A) sex-linked dominant trait.
B) sex-influenced trait.
C) sex-limited trait.
D) sex-linked recessive trait. Ans: d
A 50-year-old male was recently diagnosed with Huntington disease.
Transmission of this disease is associated with:
A) penetrance.
B) recurrence risk.
C) expressivity.
D) delayed age of onset. Ans: d
People who have neurofibromatosis will show varying degrees of the
disease; this is because of the genetic principle of:
A) penetrance.
© 2026 All rights reserved
1. Chamberlain University-Illinois
2. NR 222
Pathophysiology Exam 1 Questions and
Answers 2026 Latest
An ordered photographic display of a set of chromosomes from a single cell
is a(n):
A) metaphase spread.
B) autosomal spread.
C) karyotype.
D) anaphase spread. Ans: c
An error in which homologous chromosomes fail to separate during meiosis
is termed:
A) aneuploidy.
B) nondisjunction.
C) polyploidy.
D) anaplasia. Ans: b
A somatic cell that does not contain a multiple of 23 chromosomes is called:
A) an aneuploid cell.
B) a euploid cell.
C) a polyploidy cell.
D) a haploid cell. Ans: a
© 2026 All rights reserved
, 2 | Page
A 20-year-old pregnant female gives birth to a stillborn child. Autopsy
reveals that the fetus has 92 chromosomes. Which of the following
describes this condition?
A) Euploidy
B) Triploidy
C) Tetraploidy
D) Aneuploidy Ans: c
If a person is a chromosomal mosaic, the person may:
A) be a carrier of the genetic disease.
B) have a mild form of the genetic disease.
C) have two genetic diseases.
D) be sterile as a result of the genetic disease. Ans: b
The most common cause of Down syndrome is:
A) paternal nondisjunction.
B) maternal translocations.
C) maternal nondisjunction.
D) paternal translocations. Ans: c
Risk factors for Down syndrome include:
A) fetal exposure to mutagens in the uterus.
B) increased paternal age.
C) family history of Down syndrome.
D) pregnancy in women over age 35. Ans: d
A 13-year-old girl has a karyotype that reveals an absent homologous X
chromosome with only a single X chromosome present. Her condition is
called:
© 2026 All rights reserved
, 3 | Page
A) Down syndrome.
B) Cri du chat syndrome.
C) Turner syndrome.
D) Edward syndrome Ans: c
A child is diagnosed with cystic fibrosis. History reveals that the child's
parents are first cousins. Cystic fibrosis was most likely the result of:
A) X inactivation.
B) genomic imprinting.
C) consanguinity.
D) obligate carriers. Ans: c
Joey, age 9, is admitted to a pediatric unit with Duchenne muscular
dystrophy. He inherited this condition through a:
A) sex-linked dominant trait.
B) sex-influenced trait.
C) sex-limited trait.
D) sex-linked recessive trait. Ans: d
A 50-year-old male was recently diagnosed with Huntington disease.
Transmission of this disease is associated with:
A) penetrance.
B) recurrence risk.
C) expressivity.
D) delayed age of onset. Ans: d
People who have neurofibromatosis will show varying degrees of the
disease; this is because of the genetic principle of:
A) penetrance.
© 2026 All rights reserved
