APEA Pharm Cardiovascular EXAM
QUESTIONS WITH CORRECT
SOLUTIONS||100% GUARANTEED
PASS||ALREADY GRADED
A+||UPDATED 2026/2027
SYLLABUS||<<NEWEST VERSION>>
To reduce the flushing effects caused by nifedipine (Adalat CC), it should be taken
with:
grapefruit.
milk.
an aspirin.
low-fat meals. - ANSWER ✓ low-fat meals.
The peak effect of enalapril (Vasotec), an angiotensin-converting enzyme (ACE)
inhibitor, occurs in:
1 hour.
3 hours.
5 hours.
8 hours. - ANSWER ✓ 5 hours.
Ranolazine (Ranexa) is indicated in the treatment of:
acute angina.
acute coronary syndrome.
intermittent claudication.
chronic angina. - ANSWER ✓ chronic angina.
Ranolazine (Ranexa) is indicated in the treatment of chronic angina. It exerts
antianginal and anti-ischemic effects without changing heart rate or blood pressure.
Enoxaparin (Lovenox) is classified as a(n):
ADP receptor antagonist.
factor Xa inhibitor.
,low molecular weight heparin.
direct thrombin inhibitor. - ANSWER ✓ low molecular weight heparin.
Gemfibrozil (Lopid), for the treatment of hypertriglyceridemia, is classified as a:
bile acid sequestrant.
nicotinic acid.
fibric acid.
statin. - ANSWER ✓ fibric acid.
For the patient receiving dabigatran (Pradaxa) who needs anticoagulation reversal,
the nurse practitioner knows that:
no reversal agent is available.
vitamin K should be administered.
idarucizumab (Praxbind) is the emergency reversal agent.
administration of fresh frozen plasma is the only available option. - ANSWER ✓
idarucizumab (Praxbind) is the emergency reversal agent.
Of the angiotensin receptor blockers (ARBs) used in the treatment of
hypertension, the one with the longest biological half-life at 24 hours is:
irbesartan (Avapro).
losartan (Cozaar).
olmesartan (Benicar).
telmisartan (Micardis). - ANSWER ✓ telmisartan (Micardis).
Avoid concomitant use of oral digoxin (Lanoxin) and:
amoxicillin (Amoxil).
famotidine (Pepcid).
acetaminophen (Tylenol).
levothyroxine (Synthroid). - ANSWER ✓ famotidine (Pepcid)
PPIs & H2 receptor blockers should NOT be used concomitantly with digoxin
(Lanoxin). These medications work by decreasing the production of acid. Some
medications, like digoxin need the acid production in order to be absorbed
A common side effect of cardioselective beta-blockers such as labetalol (Trandate)
is:
weight loss.
shortness of breath.
, tachycardia.
facial swelling. - ANSWER ✓ shortness of breath.
The most common side effects of cardioselective beta-blockers (i.e., labetalol
[Trandate]) are exercise intolerance, shortness of breath, weight gain, fatigue,
bradycardia, low blood pressure, shortness of breath, and in men, erectile
dysfunction
The mechanism of action of angiotensin-converting enzyme (ACE) inhibitors in
lowering blood pressure is to:
block the formation of angiotensinogen in the liver.
convert angiotensin I to angiotensin II in the myocardium.
inhibit the enzyme that converts angiotensin I to angiotensin II in the serum.
inhibit the conversion of angiotensin enzyme production by the kidneys. -
ANSWER ✓ inhibit the enzyme that converts angiotensin I to angiotensin II in the
serum.
Spironolactone (Aldactone) is highly protein bound and has a duration of:
6 hours.
12 hours.
24 hours.
48 hours. - ANSWER ✓ 48 hours.
Cardioselective beta-blockers:
specifically block beta-1 receptors.
should never be administered to patients who have asthma.
are recommended as first-line treatment for hypertension.
should be discontinued 5 days prior to surgery. - ANSWER ✓ specifically block
beta-1 receptors.
Selective beta-blockers specifically block beta-1 receptors, although they can be
nonselective at higher doses. Beta-blockers are generally not recommended as
first-line agents for the treatment of hypertension.
A 52-year-old man is receiving metoprolol tartrate (Lopressor) after a myocardial
infarction. This patient should be educated to:
stop the medication abruptly if any side effects occur.
QUESTIONS WITH CORRECT
SOLUTIONS||100% GUARANTEED
PASS||ALREADY GRADED
A+||UPDATED 2026/2027
SYLLABUS||<<NEWEST VERSION>>
To reduce the flushing effects caused by nifedipine (Adalat CC), it should be taken
with:
grapefruit.
milk.
an aspirin.
low-fat meals. - ANSWER ✓ low-fat meals.
The peak effect of enalapril (Vasotec), an angiotensin-converting enzyme (ACE)
inhibitor, occurs in:
1 hour.
3 hours.
5 hours.
8 hours. - ANSWER ✓ 5 hours.
Ranolazine (Ranexa) is indicated in the treatment of:
acute angina.
acute coronary syndrome.
intermittent claudication.
chronic angina. - ANSWER ✓ chronic angina.
Ranolazine (Ranexa) is indicated in the treatment of chronic angina. It exerts
antianginal and anti-ischemic effects without changing heart rate or blood pressure.
Enoxaparin (Lovenox) is classified as a(n):
ADP receptor antagonist.
factor Xa inhibitor.
,low molecular weight heparin.
direct thrombin inhibitor. - ANSWER ✓ low molecular weight heparin.
Gemfibrozil (Lopid), for the treatment of hypertriglyceridemia, is classified as a:
bile acid sequestrant.
nicotinic acid.
fibric acid.
statin. - ANSWER ✓ fibric acid.
For the patient receiving dabigatran (Pradaxa) who needs anticoagulation reversal,
the nurse practitioner knows that:
no reversal agent is available.
vitamin K should be administered.
idarucizumab (Praxbind) is the emergency reversal agent.
administration of fresh frozen plasma is the only available option. - ANSWER ✓
idarucizumab (Praxbind) is the emergency reversal agent.
Of the angiotensin receptor blockers (ARBs) used in the treatment of
hypertension, the one with the longest biological half-life at 24 hours is:
irbesartan (Avapro).
losartan (Cozaar).
olmesartan (Benicar).
telmisartan (Micardis). - ANSWER ✓ telmisartan (Micardis).
Avoid concomitant use of oral digoxin (Lanoxin) and:
amoxicillin (Amoxil).
famotidine (Pepcid).
acetaminophen (Tylenol).
levothyroxine (Synthroid). - ANSWER ✓ famotidine (Pepcid)
PPIs & H2 receptor blockers should NOT be used concomitantly with digoxin
(Lanoxin). These medications work by decreasing the production of acid. Some
medications, like digoxin need the acid production in order to be absorbed
A common side effect of cardioselective beta-blockers such as labetalol (Trandate)
is:
weight loss.
shortness of breath.
, tachycardia.
facial swelling. - ANSWER ✓ shortness of breath.
The most common side effects of cardioselective beta-blockers (i.e., labetalol
[Trandate]) are exercise intolerance, shortness of breath, weight gain, fatigue,
bradycardia, low blood pressure, shortness of breath, and in men, erectile
dysfunction
The mechanism of action of angiotensin-converting enzyme (ACE) inhibitors in
lowering blood pressure is to:
block the formation of angiotensinogen in the liver.
convert angiotensin I to angiotensin II in the myocardium.
inhibit the enzyme that converts angiotensin I to angiotensin II in the serum.
inhibit the conversion of angiotensin enzyme production by the kidneys. -
ANSWER ✓ inhibit the enzyme that converts angiotensin I to angiotensin II in the
serum.
Spironolactone (Aldactone) is highly protein bound and has a duration of:
6 hours.
12 hours.
24 hours.
48 hours. - ANSWER ✓ 48 hours.
Cardioselective beta-blockers:
specifically block beta-1 receptors.
should never be administered to patients who have asthma.
are recommended as first-line treatment for hypertension.
should be discontinued 5 days prior to surgery. - ANSWER ✓ specifically block
beta-1 receptors.
Selective beta-blockers specifically block beta-1 receptors, although they can be
nonselective at higher doses. Beta-blockers are generally not recommended as
first-line agents for the treatment of hypertension.
A 52-year-old man is receiving metoprolol tartrate (Lopressor) after a myocardial
infarction. This patient should be educated to:
stop the medication abruptly if any side effects occur.
