VERIFIED ANSWERS 2025/2026
inattention, hyperactivity, and impulsivity - CORRECT ANSWER ADHD is noted for a
trio of symptoms what are they?
executive dysfunction - CORRECT ANSWER The prominent symptom of ADHD can
also be described as what?
dorsolateral prefrontal cortex - CORRECT ANSWER Executive dysfunction is
hypothetically linked to ineffective information processing where?
prefrontal cortical areas - CORRECT ANSWER The symptoms of ADHD may occur
because patients do not activate what is in response to cognitive tasks and
problem-solving?
ADHD - CORRECT ANSWER The firing of NE neurons innervating the prefrontal
cortex low in what?
Low NE tone - CORRECT ANSWER What hypothetically contributes to the cognitive
dysfunction in ADHD?
the most sensitive noradrenergic receptors on postsynaptic neurons - CORRECT
ANSWER Low NE tone hypothetically contributes to the cognitive dysfunction in
ADHD and preferentially stimulates what?
, tonic DA stimulation - CORRECT ANSWER If the firing of DA neurons innervating
the prefrontal cortex is also too low in ADHD there would hypothetically be
inadequately what?
post synaptic neurons but inadequately stimulates D1 - CORRECT ANSWER Low
release of DA preferentially stimulates the most sensitive DA receptors on what?
naturally rewarding experiences - CORRECT ANSWER Phasic DA release is thought
to reinforce learning and reward conditioning, providing the motivation to pursue
what?
neither under-stimulated nor overstimulated - CORRECT ANSWER Postsynaptic D1
receptors predominate in the prefrontal cortex and the best functional outcome is
when they are tunes and what?
gate incoming signals - CORRECT ANSWER Alpha 2A and D1 receptors in the
prefrontal cortex are often located on the spines of cortical neurons and can thus
do what?
hyperpolarization-activated cyclic nucleotide-gated cation channels - CORRECT
ANSWER The cAMP molecule links the receptors to what?
HCN channel - CORRECT ANSWER When NE or a noradrenergic agonist, binds to
an alpha 2a receptor, the activated Gi-linked inhibits cAMP thereby closing what?
an incoming signal - CORRECT ANSWER The prefrontal cortex stimulation of alpha
2a receptors strengthens what?