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HESI Pharmacology V1 2026 – 95 Verified Questions and Correct Answers – Antibiotics, CNS Drugs, Cardiovascular, Insulin, and Antidotes

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This verified study guide includes 95 high-yield questions and correct answers from Version 1 of the HESI Pharmacology Exam (2026 edition). Crafted to align with the HESI testing format, this guide provides clinical reasoning and pharmacological detail across the most frequently tested drug classes. Each question is paired with its correct answer and reflects real exam difficulty, making it ideal for focused, time-efficient prep. Covered topics include: Cardiovascular medications (ACE inhibitors, beta blockers, antiarrhythmics, antihypertensives) CNS agents: antidepressants (SSRIs, TCAs, MAOIs), benzodiazepines, antipsychotics, and anticonvulsants Insulin types and administration protocols (e.g., regular, rapid-acting, mixing instructions) Antibiotics and antimicrobial stewardship, including drug interactions and patient education Antidotes and toxicity management for common meds: Digoxin, Heparin, Tylenol, Warfarin, Benzos Side effects, contraindications, and nursing responsibilities for drugs like vancomycin, lithium, prednisone, morphine, and phenytoin Understanding lab values, monitoring parameters, and client education for each pharmacologic class Realistic exam questions involving route, dosage, timing, adverse effects, and lifespan considerations This document is perfect for: Students preparing for the HESI Pharmacology Version 1 exam RN, LPN, or vocational nursing students needing clinical-level pharmacology review Pharmacy technician trainees, pre-med students, or allied health learners Educators creating test banks or looking for pre-verified practice material Whether reviewing insulin types, psych meds, or antidotes, this practice set mirrors HESI logic and clinical thinking expectations. Keywords: HESI V1 pharmacology, 2026 pharmacology exam, medication safety, insulin protocols, antidotes, cardiovascular drugs, nursing pharmacology, antibiotics, CNS agents, drug side effects, nursing interventions, phenytoin, NCLEX prep, drug administration, verified answers

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HESI Pharmacology V1 2026
Exam Questions and Correct
Answers | New Update



A nurse is caring for a client with hyperparathyroidism and notes that the

client's serum calcium level is 13 mg/dL. Which medication should the

nurse prepare to administer as prescribed to the client?1. Calcium chloride

2. Calcium gluconate

3. Calcitonin (Miacalcin)


4. Large doses of vitamin D - 🧠 ANSWER ✔✔3. Calcitonin (Miacalcin)

,Rationale:

The normal serum calcium level is 8.6 to 10.0 mg/dL. This client is

experiencing hypercalcemia. Calcium gluconate and calcium chloride are

medications used for the treatment of tetany, which occurs as a result of

acute hypocalcemia. In hypercalcemia, large doses of vitamin D need to be

avoided. Calcitonin, a thyroid hormone, decreases the plasma calcium level

by inhibiting bone resorption and lowering the serum calcium concentration.

Oral iron supplements are prescribed for a 6-year-old child with iron

deficiency anemia. The nurse instructs the mother to administer the iron

with which best food item?

1. Milk

2. Water

3. Apple juice


4. Orange juice - 🧠 ANSWER ✔✔4. Orange juice




Rationale:

,Vitamin C increases the absorption of iron by the body. The mother should

be instructed to administer the medication with a citrus fruit or a juice that is

high in vitamin C. Milk may affect absorption of the iron. Water will not

assist in absorption. Orange juice contains a greater amount of vitamin C

than apple juice.

Salicylic acid is prescribed for a client with a diagnosis of psoriasis. The

nurse monitors the client, knowing that which of the following would

indicate the presence of systemic toxicity from this medication?

1. Tinnitus

2. Diarrhea

3. Constipation


4. Decreased Respirations - 🧠 ANSWER ✔✔1. Tinnitus




Rationale:

Salicylic acid is absorbed readily through the skin, and systemic toxicity

(salicylism) can result. Symptoms include tinnitus, dizziness, hyperpnea,

and psychological disturbances. Constipation and diarrhea are not

associated with salicylism.


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, The camp nurse asks the children preparing to swim in the lake if they have

applied sunscreen. The nurse reminds the children that chemical

sunscreens are most effective when applied:

1. Immediately before swimming

2. 15 minutes before exposure to the sun

3. Immediately before exposure to the sun


4. At least 30 minutes before exposure to the sun - 🧠 ANSWER ✔✔4. At

least 30 minutes before exposure to the sun




Rationale:

Sunscreens are most effective when applied at least 30 minutes before

exposure to the sun so that they can penetrate the skin. All sunscreens

should be reapplied after swimming or sweating

Mafenide acetate (Sulfamylon) is prescribed for the client with a burn injury.

When applying the medication, the client complains of local discomfort and

burning. Which of the following is the most appropriate nursing action?

1. Notifying the registered nurse

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