CHEM 121
LAB REPORT
Experiment #: 8 Organic Synthesis
Foundations of General Chemistry w/ Lab
Portage Learning, Geneva College
, Chemistry Lab Report
Experiment #: 8
Title: Organic Synthesis
Purpose: In this lab, three carbon based organic compounds were synthesized to determine
their true purity. The experiments were done to learn about how to use these compounds’ melting
points and infrared spectroscopy to determine their percent yield.
Procedure:
Experiment 1: Making Acetylsalicylic Acid (aspirin)
1. Obtain a flask.
2. Weigh 2 grams of salicylic acid.
3. Put the 2 grams of salicylic acid into the flask.
4. Put 5 mL of acetic anhydride into a graduated cylinder.
5. Add the acetic anhydride into the flask with salicylic acid.
6. It will require a catalyst therefore place 5 drops of sulfuric acid H2SO4 into the flask.
7. The substance should turn faint yellow.
8. Place into a hot water bath for 15 minutes.
9. While its heating, one of the acetyl groups from acetic anhydride will replace hydrogen on
the oxygen of salicylic acid and make the acetylsalicylic acid.
10. Heat for 15 minutes and most of the solid has dissolved (suspension).
11. Add a little bit of water into the flask while it’s still hot to use up any unreacted acetic
anhydride because the acetic anhydride actually is present in excess. (Destroys leftover
acetic anhydride).
12. Let the flask cool for a few minutes.
13. Add 40mL of ice water into the flask.
14. It will become non-see through, and a white solid will be forming. The aspirin is
crystalizing out just by adding some water. Aspirin is insoluble in water.
15. Cool the flask in an ice water bath.
16. While it is cooling, scratch the bottom of the flask to help induce crystallization of the
solid. Scratches give a place to crystallize, and it helps the solid crystallize better.
17. Keep returning it in the ice water bath to cool.
18. Synthesize the white solid by suction filtration.
19. Attach the flask to tubing that’s attached to a water aspirator.
20. Have a cup of ice water ready during this process.
21. Turn on the water aspirator.
22. Pour the content in the original flask into the filtration.
23. Once its empty, pour a little bit of ice water into the original flask, swirl it around and then
pour the rest of the content into the filtration.
24. Repeat one more time.
25. Wait for the filtration process to finish.
26. Turn off the water aspirator.
This study source was downloaded by 100000902171055 from CourseHero.com on 12-01-2025 20:38:36 GMT -06:00
https://www.coursehero.com/file/210281573/Chemistry-Lab-Report-8docx/
LAB REPORT
Experiment #: 8 Organic Synthesis
Foundations of General Chemistry w/ Lab
Portage Learning, Geneva College
, Chemistry Lab Report
Experiment #: 8
Title: Organic Synthesis
Purpose: In this lab, three carbon based organic compounds were synthesized to determine
their true purity. The experiments were done to learn about how to use these compounds’ melting
points and infrared spectroscopy to determine their percent yield.
Procedure:
Experiment 1: Making Acetylsalicylic Acid (aspirin)
1. Obtain a flask.
2. Weigh 2 grams of salicylic acid.
3. Put the 2 grams of salicylic acid into the flask.
4. Put 5 mL of acetic anhydride into a graduated cylinder.
5. Add the acetic anhydride into the flask with salicylic acid.
6. It will require a catalyst therefore place 5 drops of sulfuric acid H2SO4 into the flask.
7. The substance should turn faint yellow.
8. Place into a hot water bath for 15 minutes.
9. While its heating, one of the acetyl groups from acetic anhydride will replace hydrogen on
the oxygen of salicylic acid and make the acetylsalicylic acid.
10. Heat for 15 minutes and most of the solid has dissolved (suspension).
11. Add a little bit of water into the flask while it’s still hot to use up any unreacted acetic
anhydride because the acetic anhydride actually is present in excess. (Destroys leftover
acetic anhydride).
12. Let the flask cool for a few minutes.
13. Add 40mL of ice water into the flask.
14. It will become non-see through, and a white solid will be forming. The aspirin is
crystalizing out just by adding some water. Aspirin is insoluble in water.
15. Cool the flask in an ice water bath.
16. While it is cooling, scratch the bottom of the flask to help induce crystallization of the
solid. Scratches give a place to crystallize, and it helps the solid crystallize better.
17. Keep returning it in the ice water bath to cool.
18. Synthesize the white solid by suction filtration.
19. Attach the flask to tubing that’s attached to a water aspirator.
20. Have a cup of ice water ready during this process.
21. Turn on the water aspirator.
22. Pour the content in the original flask into the filtration.
23. Once its empty, pour a little bit of ice water into the original flask, swirl it around and then
pour the rest of the content into the filtration.
24. Repeat one more time.
25. Wait for the filtration process to finish.
26. Turn off the water aspirator.
This study source was downloaded by 100000902171055 from CourseHero.com on 12-01-2025 20:38:36 GMT -06:00
https://www.coursehero.com/file/210281573/Chemistry-Lab-Report-8docx/
