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HESI Exit Exam Test Bank 2025/2026: Comprehensive Nursing Study Guide – 600+ Verified Q&A with In-Depth Rationales for RN & LPN Success

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Prepare to pass your HESI Exit Exam on the first attempt with this definitive 2025/2026 test bank. This resource provides verified questions and answers paired with detailed rationales designed to build the clinical judgment necessary for nursing success. Key Nursing Categories & Clinical Topics Covered: • Medical-Surgical Nursing: Mastery of high-yield topics including hypertension management, COPD protocols, tracheostomy care, myocardial infarction (MONA), and GI disorders like duodenal ulcers. • Maternity & OB Nursing: Critical care scenarios for preeclampsia, umbilical cord prolapse, gestational diabetes, and the stages of labor. • Pediatric Nursing: Essential knowledge on Sickle Cell crisis, nephrotic syndrome, cleft lip feeding techniques, and tetanus precautions. • Pharmacology: Comprehensive review of Warfarin (Coumadin) dietary restrictions, Digoxin toxicity, insulin types and durations, and antihypertensives. • Mental Health & Psych: Management of major depressive disorder, bipolar disorder (Lithium/Valproic Acid), and antisocial personality disorder. • Fundamentals & Skills: Detailed guides on NG tube insertion and placement, sterile technique, and Glasgow Coma Scale (GCS) assessments. • Patient Safety & Legalities: Application of RACE/PASS fire safety, HIPAA privacy, informed consent, and delegation to UAPs. This study guide also includes dosage calculations and Arterial Blood Gas (ABG) interpretation to ensure total exam readiness.

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Comprehensive HESI Exit Exam Test Bank |
Verified Q&A with In-Depth Rationales for
Nursing Success.


Following discharge teaching, a male client with duodenal ulcer tells the
nurse the he will drink plenty of dairy products, such as milk, to help
coat and protect his ulcer. What is the best follow-up action by the
nurse?
a. Remind the client that it is also important to switch to decaffeinated
coffee and tea.
b. Suggest that the client also plan to eat frequent small meals to reduce
discomfort
c. Review with the client the need to avoid foods that are rich in milk
and cream.
d. Reinforce this teaching by asking the client to list a dairy food that he
might select. - ANSWER-c. Review with the client the need to avoid
foods that are rich in milk and cream.

The nurse observes an unlicensed assistive personnel (UAP) positioning
a newly admitted client who has a seizure disorder. The client is supine
and the UAP is placing soft pillows along the side rails. What action
should the nurse implement?
a. Ensure that the UAP has placed the pillows effectively to protect the
client.
b. Instruct the UAP to obtain soft blankets to secure to the side rails
instead of pillows.
c. Assume responsibility for placing the pillows while the UAP
completes another task.
d. Ask the UAP to use some of the pillows to prop the client in a side
lying position. - ANSWER-b. Instruct the UAP to obtain soft blankets to
secure to the side rails instead of pillows.

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A male client with hypertension, who received new antihypertensive
prescriptions at his last visit returns to the clinic two weeks later to
evaluate his blood pressure (BP). His BP is 158/106 and he admits that
he has not been taking the prescribed medication because the drugs
make him "feel bad". In explaining the need for hypertension control,
the nurse should stress that an elevated BP places the client at risk for
which pathophysiological condition?
a. Blindness secondary to cataracts
b. Acute kidney injury due to glomerular damage
c. Stroke secondary to hemorrhage
d. Heart block due to myocardial damage - ANSWER-c. Stroke
secondary to hemorrhage

An adolescent with major depressive disorder has been taking duloxetine
(Cymbalta) for the past 12 days. Which assessment finding requires
immediate follow-up
a. Describes life without purpose
b. Complains of nausea and loss of appetite
c. States is often fatigued and drowsy
d. Exhibits an increase in sweating. - ANSWER-a. Describes life
without purpose

A 60-year-old female client with a positive family history of ovarian
cancer has developed an abdominal mass and is being evaluated for
possible ovarian cancer. Her Papanicolau (Pap) smear results are
negative. What information should the nurse include in the client's
teaching plan
a. Further evaluation involving surgery may be needed
b. A pelvic exam is also needed before cancer is ruled out
c. Pap smear evaluation should be continued every six month
d. One additional negative pap smear in six months is needed. -
ANSWER-a. Further evaluation involving surgery may be needed

,3|Page


A client who recently underwent a tracheostomy is being prepared for
discharge to home. Which instructions is most important for the nurse to
include in the discharge plan?
a. Explain how to use communication tools.
b. Teach tracheal suctioning techniques
c. Encourage self-care and independence.
d. Demonstrate how to clean tracheostomy site. - ANSWER-b. Teach
tracheal suctioning techniques

In assessing an adult client with a partial rebreather mask, the nurse
notes that the oxygen reservoir bag does not deflate completely during
inspiration and the client's respiratory rate is 14 breaths / minute. What
action should the nurse implement
a. Encourage the client to take deep breaths
b. Remove the mask to deflate the bag
c. Increase the liter flow of oxygen
d. Document the assessment data - ANSWER-d. Document the
assessment data

During shift report, the central electrocardiogram (EKG) monitoring
system alarms. Which client alarm should the nurse investigate first?
a. Respiratory apnea of 30 seconds
b. Oxygen saturation rate of 88%
c. Eight premature ventricular beats every minute
d. Disconnected monitor signal for the last 6 minutes. - ANSWER-a.
Respiratory apnea of 30 seconds

During a home visit, the nurse observed an elderly client with diabetes
slip and fall. What action should the nurse take first?

a. Give the client 4 ounces of orange juice
b. Call 911 to summon emergency assistance
c. Check the client for lacerations or fractures
d. Asses clients blood sugar level - ANSWER-c. Check the client for
lacerations or fractures

, 4|Page




At 0600 while admitting a woman for a schedule repeat cesarean section
(C-Section), the client tells the nurse that she drank a cup a coffee at
0400 because she wanted to avoid getting a headache. Which action
should the nurse take first?
a. Ensure preoperative lab results are available
b. Start prescribed IV with lactated Ringer's
c. Inform the anesthesia care provider
d. Contact the client's obstetrician. - ANSWER-c. Inform the anesthesia
care provider

After placing a stethoscope as seen in the picture, the nurse auscultates
S1 and S2 heart sounds. To determine if an S3 heart sound is present,
what action should the nurse take first
a. Side the stethoscope across the sternum.
b. Move the stethoscope to the mitral site
c. Listen with the bell at the same location
d. Observe the cardiac telemetry monitor - ANSWER-c. Listen with the
bell at the same location

A 66-year-old woman is retiring and will no longer have a health
insurance through her place of employment. Which agency should the
client be referred to by the employee health nurse for health insurance
needs?
a. Woman, Infant, and Children program
b. Medicaid
c. Medicare
d. Consolidated Omnibus Budget Reconciliation Act provision. -
ANSWER-c. Medicare

A client who is taking an oral dose of a tetracycline complains of
gastrointestinal upset. What snack should the nurse instruct the client to
take with the tetracycline?
a. Fruit-flavored yogurt.
b. Cheese and crackers.

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