Chapter 13: DNA
13.1 Identifying the substances of genes
● A. Griffith 1928
1. Goal
● Find out how certain types of bacteria cause pneumonia
2. Looked at 2 strains of bacteria
● A. S strain-smooth colonies, causes pneumonia
● B. R strain-rough colonies do not cause pneumonia
● 3. Experiment
● A. inject mouse w/ S strain, dies
● B. inject mouse w/ R strain, lives
● C. Inject mouse w/ heat killed S, lives
● D. injects mouse w/ mixture of heat-killed S and R, dies
4. Transformation
● A. process used to explain how heat killed S strain transfers info to the R strain
● B. transforming factor must be a gene
A bacteriophage is a virus that attacks bacteria
They are either protein or DNA
Inject DNA into bacteria, protein attaches to the cell
Then it bursts and releases more viruses; that's how viruses work
2. Goal
● A. Determine which part of the virus enters the bacteria
– Protein or DNA?
3. Experiment
● A. grow bacteriophage w/ phosphorus-32 in DNA (makes bacteria radioactive)
● B. grow bacteriophage w/ sulfur-35 in protein coat (bacteria is not then radioactive)
4. Conclusion
● A. DNA is the genetic material found in genes
● B. confirmed Avery’s results
ll. Function of DNA
● A. Storing info
● B. Copy info
● C. Transmit info
–1. Pass info to next generation
lll. 13.2 Structure of DNA
13.1 Identifying the substances of genes
● A. Griffith 1928
1. Goal
● Find out how certain types of bacteria cause pneumonia
2. Looked at 2 strains of bacteria
● A. S strain-smooth colonies, causes pneumonia
● B. R strain-rough colonies do not cause pneumonia
● 3. Experiment
● A. inject mouse w/ S strain, dies
● B. inject mouse w/ R strain, lives
● C. Inject mouse w/ heat killed S, lives
● D. injects mouse w/ mixture of heat-killed S and R, dies
4. Transformation
● A. process used to explain how heat killed S strain transfers info to the R strain
● B. transforming factor must be a gene
A bacteriophage is a virus that attacks bacteria
They are either protein or DNA
Inject DNA into bacteria, protein attaches to the cell
Then it bursts and releases more viruses; that's how viruses work
2. Goal
● A. Determine which part of the virus enters the bacteria
– Protein or DNA?
3. Experiment
● A. grow bacteriophage w/ phosphorus-32 in DNA (makes bacteria radioactive)
● B. grow bacteriophage w/ sulfur-35 in protein coat (bacteria is not then radioactive)
4. Conclusion
● A. DNA is the genetic material found in genes
● B. confirmed Avery’s results
ll. Function of DNA
● A. Storing info
● B. Copy info
● C. Transmit info
–1. Pass info to next generation
lll. 13.2 Structure of DNA
