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Med Surg Exam Review 2026 – 180+ NCLEX-Style Q&As – Immunity, Renal, Respiratory, Dialysis, Transplants

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This expertly verified 180+ question-and-answer review is designed to help nursing students and NCLEX candidates master core concepts in Medical-Surgical Nursing for the 2026 exam cycle. The content is structured in a rapid-recall format and directly aligns with major test frameworks like NCLEX-RN, ATI, and HESI. It comprehensively covers immunologic, renal, respiratory, and transplant systems, along with detailed nursing interventions, pathophysiology, and lab interpretation. Key topics include: Immunity types and disorders: cell-mediated, humoral, passive, active, artificial, hypersensitivity (Type I–IV) Allergic reactions and immunotherapy management: assessment, injection techniques, documentation, anaphylaxis precautions Respiratory care: pneumothorax types, chest tube management, BiPAP/CPAP, tracheostomy post-op care, ventilator modes, suctioning protocols Renal and urinary disorders: pyelonephritis, nephrotic syndrome, glomerulonephritis, AKI phases, dialysis (hemodialysis & peritoneal), electrolyte imbalances, CKD progression Kidney transplant & rejection management: acute vs. chronic rejection, immunosuppressant therapy, graft monitoring Fluid & electrolyte monitoring, acid-base balance via ABGs, risk factor recognition, and nutrition for renal patients This resource is ideal for: RN, BSN, and LPN students preparing for Med-Surg units NCLEX-RN candidates seeking Q&A practice in immunity, renal, and respiratory systems Nursing educators building clinical quizzes or exam prep content Anyone needing a comprehensive refresher on high-yield Med-Surg topics It draws upon nursing texts such as Brunner & Suddarth’s Medical-Surgical Nursing and Lewis's Medical-Surgical Nursing, while incorporating updated exam frameworks. Keywords: Med Surg exam, NCLEX RN prep, immunity types, hypersensitivity reactions, hemodialysis, peritoneal dialysis, respiratory nursing, transplant rejection, AKI stages, CKD nursing care, BiPAP vs CPAP, tracheostomy care, chest tube, electrolyte imbalance, fluid management, ATI Med-Surg, nursing Q&A review

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Med Surg Exam Review 2026
Expert Verified | Ace the Test



Cell-mediated immunity (CMI) - 🧠 ANSWER ✔✔Immunity involving a T-cell

response


humoral immunity - 🧠 ANSWER ✔✔- IGG, IGA


specific immunity produced by B cells that produce antibodies that circulate

in body fluids


Acquired immunity: - 🧠 ANSWER ✔✔Immunity that is present only after

exposure

,Active immunity: - 🧠 ANSWER ✔✔immunity produced by exposure to an

antigen, as a result of the immune response after coming in contact with

the actual infection (ex: chicken pox, measles, mumps)


artificial immunity: - 🧠 ANSWER ✔✔immunization; immunity acquired from

a vaccination


Passive immunity: - 🧠 ANSWER ✔✔An individual does not produce his or

her own antibodies, but rather receives them directly from another source,

such as mother to infant through breast milk


Passive artificial immunity: - 🧠 ANSWER ✔✔receive antiserum with

antibodies from another host (ex: infection of hepatitis B Immune globulin to

another person who doesn't have antibodies)


Effects of aging on the immune system: - 🧠 ANSWER ✔✔- thymic atrophy

(shrinkage)

- decreased hypersensitivity response

- decreased T cell and B cells mediated response

- decreased T cell activity

-increase autoantibodies

, -decrease cell-mediated


colony stimulating factors (CSFs) - 🧠 ANSWER ✔✔-stimulate growth and

differentiation of immature leukocytes in bone marrow

-stimulates erythriod progenitor cells in bone marrow to make red blood

cells


Granulocyte colony-stimulating factor (G-CSF) - 🧠 ANSWER ✔✔-increases

number and maturity of neutrophils

- stimulates


Macrophage colony stimulating factors (M-CSF) - 🧠 ANSWER ✔✔Promotes

proliferation differentiation, and alteration of monocytes and macrophages


Cytokines: - 🧠 ANSWER ✔✔- MESSENGER INTERACT W/ WBC'S


-Chemicals released by the immune system communicate with the brain.

-complex interactions of T cells, B cells, monocytes, and neutrophils


Hypersensitivity reactions: - 🧠 ANSWER ✔✔Type I- Anaphylactic

(immediate) (ex: rash)

Type II- Cytotoxic (ex: blood transfusion reaction)



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