Immunohematology Final - Exam Questions With Complete
Solutions
1+ agglutination appears as: Correct Answers very fine
agglutinates with a red background
2+ agglutination appears as: Correct Answers Several small-
medium sized agglutinates with a clear background.
3+ agglutination appears as: Correct Answers Several large
clumps with a clear background
A benign cold autoagglutinin may cause interference in antibody
screening procedures when: Correct Answers polyspecific AHG
reagents are used in the test procedure.
A child is Kell positive. The mother is Kell negative, the alleged
father is Kell negative. What is this called? Correct Answers
Direct exclusion
A febrile transfusion reaction is usually caused by: Correct
Answers Patient Anti-HLA reacting with donor WBCs.
A newborn has the following test results:
type A pos (mother: O pos)
DAT: 1+
Bilirubin: delayed elevation
Symptoms: very mild
Anemia: mild, with microspherocytes seen on blood smear
Which type of HDFN is most likely? Correct Answers ABO
hemolytic disease of the newborn
,A patent inherited the following alleles: Lele, sese, H. What
Lewis antigen must be on the surface of their RBCs? Correct
Answers Le (a+b-)
A patient has the phenotype O, DCEe. If the patient requires
multiple packed red blood cell transfusions from different group
O positive donors, the patient could theoretically produce which
of the following antibodies? Correct Answers Anti-c
A patient inherited the following alleles: lele, Sese, H. What
Lewis antigen must be on the surface of their RBCs? Correct
Answers Le (a-b-)
*the patient lacks the Lewis allele (lele), so the secretor status
doesn't;t matter, and their RBCs will have no Lewis alleles.
A patient inherited the following alleles: Lele, Sese, H. What
Lewis antigen must be on the surface of their RBCs? Correct
Answers Le (a-b+)
*the patient has the Le allele and is a secretor (Se), so his RBCs
will only be pos for Leb.
A patient with a positive DAT needs to be phenotyped for the
Jka antigen. What reagent can be used on RBCs to ensure
accurate typing? Correct Answers Chloroquine diphosphate
A, B, and H antigens on the red blood cell surface are: Correct
Answers Glycolipids
According to AABB Standards, Weak D testing is required to be
performed in all of the following situations (a-d) except: Correct
, Answers Pre-transfusion testing for both males and females of
reproductive age.
According to the International Society of Blood Transfusion
(ISBT), the Rh system is assigned which of the following three
digit codes? Correct Answers 004
All of the following are characteristics of benign cold auto
agglutinins except: Correct Answers Antibodies usually have a
titer greater than 1000 at 4C
All of the following are classifications of immune hemolytic
anemia except: Correct Answers hyperimmune
All of the following are true of ABO antibodies except: Correct
Answers Type AB adults produce naturally occurring, broad
thermal range IgM Anti-A and Anti-B.
All of the following characteristics are true of the Bombay
Phenotype except: Correct Answers Should be given O negative
donor units if a transfusion is needed. Bombay type individuals
can only accept other Bombay type.
All of the following would be appropriate treatment for Warm
Autoimmune Hemolytic Anemia (WAIHA) except: Correct
Answers Massive transfusion of donor units of packed RBCS
All of the following would be classified as natural occurring
antibodies (produced from "look like antigens" in the
environment and not from foreign red blood cell exposure)
except: Correct Answers Anti-D
Solutions
1+ agglutination appears as: Correct Answers very fine
agglutinates with a red background
2+ agglutination appears as: Correct Answers Several small-
medium sized agglutinates with a clear background.
3+ agglutination appears as: Correct Answers Several large
clumps with a clear background
A benign cold autoagglutinin may cause interference in antibody
screening procedures when: Correct Answers polyspecific AHG
reagents are used in the test procedure.
A child is Kell positive. The mother is Kell negative, the alleged
father is Kell negative. What is this called? Correct Answers
Direct exclusion
A febrile transfusion reaction is usually caused by: Correct
Answers Patient Anti-HLA reacting with donor WBCs.
A newborn has the following test results:
type A pos (mother: O pos)
DAT: 1+
Bilirubin: delayed elevation
Symptoms: very mild
Anemia: mild, with microspherocytes seen on blood smear
Which type of HDFN is most likely? Correct Answers ABO
hemolytic disease of the newborn
,A patent inherited the following alleles: Lele, sese, H. What
Lewis antigen must be on the surface of their RBCs? Correct
Answers Le (a+b-)
A patient has the phenotype O, DCEe. If the patient requires
multiple packed red blood cell transfusions from different group
O positive donors, the patient could theoretically produce which
of the following antibodies? Correct Answers Anti-c
A patient inherited the following alleles: lele, Sese, H. What
Lewis antigen must be on the surface of their RBCs? Correct
Answers Le (a-b-)
*the patient lacks the Lewis allele (lele), so the secretor status
doesn't;t matter, and their RBCs will have no Lewis alleles.
A patient inherited the following alleles: Lele, Sese, H. What
Lewis antigen must be on the surface of their RBCs? Correct
Answers Le (a-b+)
*the patient has the Le allele and is a secretor (Se), so his RBCs
will only be pos for Leb.
A patient with a positive DAT needs to be phenotyped for the
Jka antigen. What reagent can be used on RBCs to ensure
accurate typing? Correct Answers Chloroquine diphosphate
A, B, and H antigens on the red blood cell surface are: Correct
Answers Glycolipids
According to AABB Standards, Weak D testing is required to be
performed in all of the following situations (a-d) except: Correct
, Answers Pre-transfusion testing for both males and females of
reproductive age.
According to the International Society of Blood Transfusion
(ISBT), the Rh system is assigned which of the following three
digit codes? Correct Answers 004
All of the following are characteristics of benign cold auto
agglutinins except: Correct Answers Antibodies usually have a
titer greater than 1000 at 4C
All of the following are classifications of immune hemolytic
anemia except: Correct Answers hyperimmune
All of the following are true of ABO antibodies except: Correct
Answers Type AB adults produce naturally occurring, broad
thermal range IgM Anti-A and Anti-B.
All of the following characteristics are true of the Bombay
Phenotype except: Correct Answers Should be given O negative
donor units if a transfusion is needed. Bombay type individuals
can only accept other Bombay type.
All of the following would be appropriate treatment for Warm
Autoimmune Hemolytic Anemia (WAIHA) except: Correct
Answers Massive transfusion of donor units of packed RBCS
All of the following would be classified as natural occurring
antibodies (produced from "look like antigens" in the
environment and not from foreign red blood cell exposure)
except: Correct Answers Anti-D
