BLOOD BANK FINAL EXAM QUESTIONS AND ANSWERS
Which of the following is NOT a part of a QA program? - CORRECT ANSWER✅✅viral marker testing
What criteria apply to the correction of manual records? - CORRECT ANSWER✅✅the original entry is
not deleted, the person making the correction dates and initials the change, the item is crossed out with
a single line
What is the purpose of competency assessment? - CORRECT ANSWER✅✅*identify employees in need
of retraining
*comply with regulatory standards
What does not apply to the performance of internal audits? - CORRECT ANSWER✅✅they are solely
used to identify troublemakers
Where are cGMPs applicable to the blood bank industry found? - CORRECT ANSWER✅✅FDA code of
federal regulations
WHat term describes the process to identify the factors contributing to the occurence of
nonconformance? - CORRECT ANSWER✅✅root cause analysis
government agency that regulates blood banks - CORRECT ANSWER✅✅FDA
agency responsible for safety - CORRECT ANSWER✅✅OSHA
voluntary peer review organization - CORRECT ANSWER✅✅AABB
Who is ULTIMATELY responsible for a safety program in the lab? - CORRECT ANSWER✅✅the employer
or lab director
What organization publishes the "Technical Manual" - CORRECT ANSWER✅✅AABB
,The organization that provides certified good manufacturing practices (cGMPs) for BB - CORRECT
ANSWER✅✅FDA
Term for goggles, face masks, and shields - CORRECT ANSWER✅✅PPE
Policy of treating all substances as potentially infectious - CORRECT ANSWER✅✅standard precautions
The most effective defense for infection control and safety - CORRECT ANSWER✅✅hand washing
The disinfectant used for decontamination - CORRECT ANSWER✅✅1:10 bleach dilution
When should an accident or injury be reported - CORRECT ANSWER✅✅at the time the accident or
injury occurs
The best way to keep employees and the lab safe - CORRECT ANSWER✅✅safety training
determine the degree of risk to exposure of infectious disease - CORRECT ANSWER✅✅biosafety levels
classes of medical waste per the EPA - CORRECT ANSWER✅✅micro and patho waste, blood specimens
and products, lab coats and gowns, sharps
Flash point - CORRECT ANSWER✅✅the minimum temperature at which a liquid fuel produces enough
vapor to burn
Proficiency testing should be performed by - CORRECT ANSWER✅✅all personnel who routinely
perform the procedure
Which cells produce antibodies - CORRECT ANSWER✅✅B lymphocytes that get activated and turn into
plasma cells
,term that describes the number of antigen binding sites per molecule of antibody? - CORRECT
ANSWER✅✅valency
Describes the unique part of the antigen that is recognized by a corresponding antibody - CORRECT
ANSWER✅✅epitope
Which molecule does not make a good immunogenic substance? - CORRECT ANSWER✅✅lipids
What is the chemical composition of an antibody? - CORRECT ANSWER✅✅glycoprotein
Where is the antigen located in the hemagglutination test? - CORRECT ANSWER✅✅on the RBC
membrane
What can enhance hemagglutination reactions? - CORRECT ANSWER✅✅increasing the incubation time
describes molecules that bind to an antigen to increase phagocytosis - CORRECT ANSWER✅✅opsonins
after performing a tube test, the supernatant of the test was pinkish, and the red cell button was small,
how do you interpret these results? - CORRECT ANSWER✅✅positive
many small agglutinates in a background of free cells - CORRECT ANSWER✅✅1+
to determine the presence of a red cell antibody, what is the source of antigen - CORRECT
ANSWER✅✅commercial reagent red cells
How does compliment activation demonstrate within the body? - CORRECT ANSWER✅✅cell lysis,
enhanced cell clearance, neutrophil activation, generation of vasoactive amines
, After the addition of anti-A reagent to a patient's red cell suspension, agglutination was observed. The
result with anti-B reagent was negative. What is the interpretation of this patient's ABO typing? -
CORRECT ANSWER✅✅patient is group A
contains 10 antigen binding sites - CORRECT ANSWER✅✅IgM
Produced early in an immune response - CORRECT ANSWER✅✅IgM
able to cross the placenta - CORRECT ANSWER✅✅IgG
highest plasma concentration of immunoglobulin - CORRECT ANSWER✅✅IgG
detected with antiglobulin test - CORRECT ANSWER✅✅IgG
activates the complement cascade most efficiently - CORRECT ANSWER✅✅IgM
cell involved in acquired/adaptive immunity - CORRECT ANSWER✅✅lymphocytes turn into B cells that
turn into plasma cells that make antibodies
responsible for the activation of the complement cascade - CORRECT ANSWER✅✅antibody bound to
antigen
antibodies that are considered the most dangerous clinically - CORRECT ANSWER✅✅the ones that
react at 37 degrees Celsius (IgG)
antibodies associated with ABO - CORRECT ANSWER✅✅IgM
example of innate/nonspecific immunity - CORRECT ANSWER✅✅phagocytosis
the primary immune response takes _____ days to occur - CORRECT ANSWER✅✅7-14
Which of the following is NOT a part of a QA program? - CORRECT ANSWER✅✅viral marker testing
What criteria apply to the correction of manual records? - CORRECT ANSWER✅✅the original entry is
not deleted, the person making the correction dates and initials the change, the item is crossed out with
a single line
What is the purpose of competency assessment? - CORRECT ANSWER✅✅*identify employees in need
of retraining
*comply with regulatory standards
What does not apply to the performance of internal audits? - CORRECT ANSWER✅✅they are solely
used to identify troublemakers
Where are cGMPs applicable to the blood bank industry found? - CORRECT ANSWER✅✅FDA code of
federal regulations
WHat term describes the process to identify the factors contributing to the occurence of
nonconformance? - CORRECT ANSWER✅✅root cause analysis
government agency that regulates blood banks - CORRECT ANSWER✅✅FDA
agency responsible for safety - CORRECT ANSWER✅✅OSHA
voluntary peer review organization - CORRECT ANSWER✅✅AABB
Who is ULTIMATELY responsible for a safety program in the lab? - CORRECT ANSWER✅✅the employer
or lab director
What organization publishes the "Technical Manual" - CORRECT ANSWER✅✅AABB
,The organization that provides certified good manufacturing practices (cGMPs) for BB - CORRECT
ANSWER✅✅FDA
Term for goggles, face masks, and shields - CORRECT ANSWER✅✅PPE
Policy of treating all substances as potentially infectious - CORRECT ANSWER✅✅standard precautions
The most effective defense for infection control and safety - CORRECT ANSWER✅✅hand washing
The disinfectant used for decontamination - CORRECT ANSWER✅✅1:10 bleach dilution
When should an accident or injury be reported - CORRECT ANSWER✅✅at the time the accident or
injury occurs
The best way to keep employees and the lab safe - CORRECT ANSWER✅✅safety training
determine the degree of risk to exposure of infectious disease - CORRECT ANSWER✅✅biosafety levels
classes of medical waste per the EPA - CORRECT ANSWER✅✅micro and patho waste, blood specimens
and products, lab coats and gowns, sharps
Flash point - CORRECT ANSWER✅✅the minimum temperature at which a liquid fuel produces enough
vapor to burn
Proficiency testing should be performed by - CORRECT ANSWER✅✅all personnel who routinely
perform the procedure
Which cells produce antibodies - CORRECT ANSWER✅✅B lymphocytes that get activated and turn into
plasma cells
,term that describes the number of antigen binding sites per molecule of antibody? - CORRECT
ANSWER✅✅valency
Describes the unique part of the antigen that is recognized by a corresponding antibody - CORRECT
ANSWER✅✅epitope
Which molecule does not make a good immunogenic substance? - CORRECT ANSWER✅✅lipids
What is the chemical composition of an antibody? - CORRECT ANSWER✅✅glycoprotein
Where is the antigen located in the hemagglutination test? - CORRECT ANSWER✅✅on the RBC
membrane
What can enhance hemagglutination reactions? - CORRECT ANSWER✅✅increasing the incubation time
describes molecules that bind to an antigen to increase phagocytosis - CORRECT ANSWER✅✅opsonins
after performing a tube test, the supernatant of the test was pinkish, and the red cell button was small,
how do you interpret these results? - CORRECT ANSWER✅✅positive
many small agglutinates in a background of free cells - CORRECT ANSWER✅✅1+
to determine the presence of a red cell antibody, what is the source of antigen - CORRECT
ANSWER✅✅commercial reagent red cells
How does compliment activation demonstrate within the body? - CORRECT ANSWER✅✅cell lysis,
enhanced cell clearance, neutrophil activation, generation of vasoactive amines
, After the addition of anti-A reagent to a patient's red cell suspension, agglutination was observed. The
result with anti-B reagent was negative. What is the interpretation of this patient's ABO typing? -
CORRECT ANSWER✅✅patient is group A
contains 10 antigen binding sites - CORRECT ANSWER✅✅IgM
Produced early in an immune response - CORRECT ANSWER✅✅IgM
able to cross the placenta - CORRECT ANSWER✅✅IgG
highest plasma concentration of immunoglobulin - CORRECT ANSWER✅✅IgG
detected with antiglobulin test - CORRECT ANSWER✅✅IgG
activates the complement cascade most efficiently - CORRECT ANSWER✅✅IgM
cell involved in acquired/adaptive immunity - CORRECT ANSWER✅✅lymphocytes turn into B cells that
turn into plasma cells that make antibodies
responsible for the activation of the complement cascade - CORRECT ANSWER✅✅antibody bound to
antigen
antibodies that are considered the most dangerous clinically - CORRECT ANSWER✅✅the ones that
react at 37 degrees Celsius (IgG)
antibodies associated with ABO - CORRECT ANSWER✅✅IgM
example of innate/nonspecific immunity - CORRECT ANSWER✅✅phagocytosis
the primary immune response takes _____ days to occur - CORRECT ANSWER✅✅7-14
