BLOOD BANK II FINAL EXAM QUESTIONS AND ANSWERS
where are antigens located? - CORRECT ANSWER✅✅surface of RBCs
Where are antibodies located? - CORRECT ANSWER✅✅They are found in Plasma/serum
Type of antibody greatest amount during a primary immune response? - CORRECT ANSWER✅✅IgM -
Attacks
The antibody that retains "memory" - CORRECT ANSWER✅✅IgG- Remembers
Define CLIA'88 - CORRECT ANSWER✅✅clinical laboratory improvement amendment of 1988 set federal
regulations in the lab
Define complement - CORRECT ANSWER✅✅A process of plasma proteins that enhance the immune
response
Define Autologous - CORRECT ANSWER✅✅To a transfusion where a patient receives their own
previously donated blood
Define Landsteiner's rule - CORRECT ANSWER✅✅States that ppl naturally have antibodies in their
serum against the ABO antigen.
Define Massive transfusion - CORRECT ANSWER✅✅Giving 10 or more units of RBCs
Define Absorption - CORRECT ANSWER✅✅Process used to remove specific antibodies by incubating the
serum with RBCs that possess the corresponding antigen.
Define Elution - CORRECT ANSWER✅✅Process used to recover antibodies that are bound to RBCs
What does HLA stand for? - CORRECT ANSWER✅✅Human Leukocyte Antigen
, On which chromosome are HLA genes located? - CORRECT ANSWER✅✅Chromosome 6
What do HLA genes code for? - CORRECT ANSWER✅✅Proteins on the surface of cells
Why are HLA proteins important? - CORRECT ANSWER✅✅They are crucial for immune system
recognition.
what happens during an antigen/antibody reaction - CORRECT ANSWER✅✅Antigens and antibodies
bind together which leads to agglutination
List the 5 classes of immunoglobulins - CORRECT ANSWER✅✅IgM, IgG, IgA, IgD, IgE
What is the optimum reaction temp for IgM, IgG? - CORRECT ANSWER✅✅IgG = 37
IgM= Room Temp.
Which Ig can cross the placenta? - CORRECT ANSWER✅✅IgG
How can a pretransfusion sample be saved in the refrigerator? - CORRECT ANSWER✅✅72 hours (3
days)
DAT detects what?? - CORRECT ANSWER✅✅In VIVO sensitization
Can DAT detect AIHA when it occurs? - CORRECT ANSWER✅✅True
IAT detects what? - CORRECT ANSWER✅✅In VITRO sensitization
What are the 4 major blood groups? - CORRECT ANSWER✅✅A, B, AB, O
where are antigens located? - CORRECT ANSWER✅✅surface of RBCs
Where are antibodies located? - CORRECT ANSWER✅✅They are found in Plasma/serum
Type of antibody greatest amount during a primary immune response? - CORRECT ANSWER✅✅IgM -
Attacks
The antibody that retains "memory" - CORRECT ANSWER✅✅IgG- Remembers
Define CLIA'88 - CORRECT ANSWER✅✅clinical laboratory improvement amendment of 1988 set federal
regulations in the lab
Define complement - CORRECT ANSWER✅✅A process of plasma proteins that enhance the immune
response
Define Autologous - CORRECT ANSWER✅✅To a transfusion where a patient receives their own
previously donated blood
Define Landsteiner's rule - CORRECT ANSWER✅✅States that ppl naturally have antibodies in their
serum against the ABO antigen.
Define Massive transfusion - CORRECT ANSWER✅✅Giving 10 or more units of RBCs
Define Absorption - CORRECT ANSWER✅✅Process used to remove specific antibodies by incubating the
serum with RBCs that possess the corresponding antigen.
Define Elution - CORRECT ANSWER✅✅Process used to recover antibodies that are bound to RBCs
What does HLA stand for? - CORRECT ANSWER✅✅Human Leukocyte Antigen
, On which chromosome are HLA genes located? - CORRECT ANSWER✅✅Chromosome 6
What do HLA genes code for? - CORRECT ANSWER✅✅Proteins on the surface of cells
Why are HLA proteins important? - CORRECT ANSWER✅✅They are crucial for immune system
recognition.
what happens during an antigen/antibody reaction - CORRECT ANSWER✅✅Antigens and antibodies
bind together which leads to agglutination
List the 5 classes of immunoglobulins - CORRECT ANSWER✅✅IgM, IgG, IgA, IgD, IgE
What is the optimum reaction temp for IgM, IgG? - CORRECT ANSWER✅✅IgG = 37
IgM= Room Temp.
Which Ig can cross the placenta? - CORRECT ANSWER✅✅IgG
How can a pretransfusion sample be saved in the refrigerator? - CORRECT ANSWER✅✅72 hours (3
days)
DAT detects what?? - CORRECT ANSWER✅✅In VIVO sensitization
Can DAT detect AIHA when it occurs? - CORRECT ANSWER✅✅True
IAT detects what? - CORRECT ANSWER✅✅In VITRO sensitization
What are the 4 major blood groups? - CORRECT ANSWER✅✅A, B, AB, O
