, Malignant early cells (blasts, promyelocytes) from an acute myeloid leukemia
(promyelocytic leukemia) M3
Courtesy of Jean-Philippe Defour & Violaine Havelange, Hôpital St Luc
The block in differentiation can be partially overcome by all-trans retinoic acid which is a drug
,
, Step-by-step onconesis in colorectal cancer and its genetic basis
Molecular Cell Biology 7th Edition,
Lodish et al., 2012