Page 1 PHMY 771_ DRUG QUIZ 2
Accupril quinapril
Accuretic quinapril/HCTZ
additional common indication of bisoprolol heart failure
additional common indication of carvedilol (Coreg) heart failure
additional common indication of metoprolol succinate (Toprol heart failure
XL)
Altace ramipril
PHMY 771_ DRUG QUIZ 2 1
,Page 2 PHMY 771_ DRUG QUIZ 2
amiodarone (Cordarone) counseling points avoid grapefruit
amiodarone (Cordarone) drug interactions as an inhibitor of CYP450, 2C9, 3A4 andn P-gp (so has many drug interactions!) Ex:
increases concentrations of digoxin, warfarin, simvastatin and lovastatin) do not use with
sofosbuvir (increase bradycardia)
Amiodarone (Cordarone) notes contains iodine, avoid in pregnancy when possible (teratogenic and excreted in breast milk)
Antara fenofibrate (micronized capsule)
ARBs drug interactions do not use with ACEi or ARNI. increased risk of lithium toxicity
Atacand candesartan
PHMY 771_ DRUG QUIZ 2 2
,Page 3 PHMY 771_ DRUG QUIZ 2
Atacand HCT candesartan/HCTZ
Avalide irbesartan/HCTZ
Avapro irbesartan
BBW of ACEi fetal harm and death (avoid in pregancy)
BBW of amiodarone (Cordarone) pulmonary toxicity, hepatotoxicity
BBW of ARBs fetal harm and death. Avoid in pregnancy
PHMY 771_ DRUG QUIZ 2 3
, Page 4 PHMY 771_ DRUG QUIZ 2
BBW of beta blockers do not discontinue abruptly-gradually taper over 1-2 weeks
BBW of flecainide acetate (Tambocor) proarrhythmic effects (especially in AFib)
BBW of sacubitril/valsartan (Entresto) fetal harm and death (avoid in pregnancy)
BBW of sotalol adjust dosing based on CrCl to decrease risk of proarrhythmia. QT prolongation. Initiate in
the hopsital
Benicar olmesartan
Benicar HCT olmesartan/HCTZ
PHMY 771_ DRUG QUIZ 2 4
Accupril quinapril
Accuretic quinapril/HCTZ
additional common indication of bisoprolol heart failure
additional common indication of carvedilol (Coreg) heart failure
additional common indication of metoprolol succinate (Toprol heart failure
XL)
Altace ramipril
PHMY 771_ DRUG QUIZ 2 1
,Page 2 PHMY 771_ DRUG QUIZ 2
amiodarone (Cordarone) counseling points avoid grapefruit
amiodarone (Cordarone) drug interactions as an inhibitor of CYP450, 2C9, 3A4 andn P-gp (so has many drug interactions!) Ex:
increases concentrations of digoxin, warfarin, simvastatin and lovastatin) do not use with
sofosbuvir (increase bradycardia)
Amiodarone (Cordarone) notes contains iodine, avoid in pregnancy when possible (teratogenic and excreted in breast milk)
Antara fenofibrate (micronized capsule)
ARBs drug interactions do not use with ACEi or ARNI. increased risk of lithium toxicity
Atacand candesartan
PHMY 771_ DRUG QUIZ 2 2
,Page 3 PHMY 771_ DRUG QUIZ 2
Atacand HCT candesartan/HCTZ
Avalide irbesartan/HCTZ
Avapro irbesartan
BBW of ACEi fetal harm and death (avoid in pregancy)
BBW of amiodarone (Cordarone) pulmonary toxicity, hepatotoxicity
BBW of ARBs fetal harm and death. Avoid in pregnancy
PHMY 771_ DRUG QUIZ 2 3
, Page 4 PHMY 771_ DRUG QUIZ 2
BBW of beta blockers do not discontinue abruptly-gradually taper over 1-2 weeks
BBW of flecainide acetate (Tambocor) proarrhythmic effects (especially in AFib)
BBW of sacubitril/valsartan (Entresto) fetal harm and death (avoid in pregnancy)
BBW of sotalol adjust dosing based on CrCl to decrease risk of proarrhythmia. QT prolongation. Initiate in
the hopsital
Benicar olmesartan
Benicar HCT olmesartan/HCTZ
PHMY 771_ DRUG QUIZ 2 4
