Psychopharmacology Drugs Brain Behavior 3rd Edition Meyer | Nursing Textbook

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ChapterJ1:JPrinciplesJofJPharmacology

MultipleJChoice

1. refer(s)JtoJspecificJmolecularJchangesJthatJoccurJwhenJaJdrugJbindsJtoJaJpart
icularJtargetJsiteJorJreceptor,Jwhile
areJtheJresultingJwidespreadJalterationsJinJfunction.
a. DrugJaction;JtherapeuticJeffects
b. SideJeffects;JdrugJeffects
c. TherapeuticJeffects;JsideJeffects
d. DrugJaction;JdrugJeffects
Answer:Jd
TextbookJReference:JPharmacology:JTheJScienceJofJDrugJAction

2. AfterJdrugJadministrationJhasJoccurred,JtheJamountJofJdrugJinJtheJbloodJthatJisJfreeJtoJ
bindJatJspecificJtargetJsitesJisJreferredJtoJas
a. theJtherapeuticJdose.
b. first-passJeffects.
c. bioavailability.
d. ED50.
Answer:Jc
TextbookJReference:JPharmacokineticJFactorsJDeterminingJDrugJAction

3. TheJspecificJmolecularJchangesJthatJoccurJwhenJaJdrugJbindsJtoJaJparticularJtargetJsiteJ
orJreceptorJareJreferredJtoJas
a. drugJeffects.
b. drugJaction.
c. sideJeffects.
d. placeboJeffects.
Answer:Jb
TextbookJReference:JPharmacology:JTheJScienceJofJDrugJAction

4. WhichJofJtheJfollowingJisJnotJaJpossibleJexplanationJforJplaceboJeffects?
a. PavlovianJconditioning
b. GeneticJvariation
c. DrugJcompetition
d. ExpectationJofJoutcome
Answer:Jc
TextbookJReference:JPharmacology:JTheJScienceJofJDrugJAction




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5. The administrationJofJoxytocinJhasJbeenJproposedJasJaJtreatmentJforJautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer:Jc
TextbookJReference:JPharmacokineticJFactorsJDeterminingJDrugJAction

6. WhichJfactorJdoesJnotJaffectJtheJpharmacokineticsJofJaJdrug?
a. RouteJofJadministration
b. LipidJsolubility
c. DepotJbinding
d. DrugJaction
Answer:Jd
TextbookJReference:JPharmacokineticJFactorsJDeterminingJDrugJAction

7. First-passJmetabolismJoccursJwhenJdrugsJareJtaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer:Ja
TextbookJReference:JPharmacokineticJFactorsJDeterminingJDrugJAction

8. TheJareaJpostremaJisJoneJareaJinJtheJbrainJwhereJthe isJnotJcomplete.
a. cerebrospinalJfluid
b. blood–brainJbarrier
c. choroidJplexus
d. phospholipidJmembrane
Answer:Jb
TextbookJReference:JPharmacokineticJFactorsJDeterminingJDrugJAction

9. First-passJmetabolismJoccursJwithJorallyJadministeredJdrugsJbecause
a. theirJabsorptionJisJslowedJbyJfood.
b. drugsJabsorbedJintoJtheJbloodstreamJfromJtheJstomachJgoJtoJtheJliverJonJtheJwayJtoJ
generalJcirculation.
c. drugsJmustJfirstJsurviveJtheJacidicJenvironmentJofJtheJstomach.
d. salivaryJenzymesJinJtheJmouthJbeginJtheJprocessJofJmetabolism.
Answer:Jb
TextbookJReference:JPharmacokineticJFactorsJDeterminingJDrugJAction

10. ToxicJsubstancesJinJtheJbloodJtriggerJaJvomitingJresponseJbyJactivatingJthe
a. blood–brainJbarrier.
b. choroidJplexus.
c. areaJpostrema.
d. medianJeminence.



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Answer:Jc
TextbookJReference:JPharmacokineticJFactorsJDeterminingJDrugJAction

11. DrugsJadministeredJ_ haveJtheJmostJrapidJonsetJofJaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer:Jd
TextbookJReference:JPharmacokineticJFactorsJDeterminingJDrugJAction

12. IonizationJofJaJdrugJdependsJonJthe ofJtheJsolutionJandJthe
ofJtheJdrug.
a. pH;JpKa
b. pKa;JpH
c. concentration;JlipidJsolubility
d. pH;Jconcentration
Answer:Ja
TextbookJReference:JPharmacokineticJFactorsJDeterminingJDrugJAction

13. TheJabsorptionJofJaJdrugJdependsJonJallJofJtheJfollowingJexcept
a. lipidJsolubility.
b. ionization.
c. bodyJtemperature.
d. theJconcentrationJofJtheJdrug.
Answer:Jc
TextbookJReference:JPharmacokineticJFactorsJDeterminingJDrugJAction

14. DrugsJthatJare shouldJbeJavoidedJbyJwomenJofJchildbearingJage.
a. teratogenic
b. ableJtoJcrossJtheJplacentalJbarrier
c. psychoactive
d. highlyJlipid-soluble
Answer:Ja
TextbookJReference:JPharmacokineticJFactorsJDeterminingJDrugJAction

15. AgentsJthatJinduceJdevelopmentalJabnormalitiesJinJaJfetusJareJknownJas
a. psychoactiveJdrugs.
b. illicitJdrugs.
c. teratogens.
d. placentalJdrugs.
Answer:Jc
TextbookJReference:JPharmacokineticJFactorsJDeterminingJDrugJAction

16. DepotJbindingJisJsaidJtoJoccurJwhenJdrugs
a. bindJtoJtheirJtargetJsites.



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