PHM 350 Exam 2 Drugs Questions With
Correct Answers
Hydrochlorothiazide |- |CORRECT |ANSWER✔✔-K-Wasting |Loop |Diuretics |in |Distal |Tubule
Inhibit |passive |Na |and |Cl |reabsorption |by |symporter |in |distal |tubule
Increase |Na, |K, |Cl |and |Mg |excretion
Decrease |Ca |excretion
Treat |Hypertension
Edema |in |CHF |and |Hepatic |Cirrhosis
Trichlormethiazide |- |CORRECT |ANSWER✔✔-K-Wasting |Loop |Diuretics |in |Distal |Tubule
K-Wasting |Loop |Diuretics |in |Distal |Tubule
Inhibit |passive |Na |and |Cl |reabsorption |by |symporter |in |distal |tubule
Increase |Na, |K, |Cl |and |Mg |excretion
Decrease |Ca |excretion
Treat |Hypertension
Edema |in |CHF |and |Hepatic |Cirrhosis
Furosemide |(LASIX) |- |CORRECT |ANSWER✔✔-High |Ceiling |Loop |Diuretics
Inhibit |passive |K, |Na |and |Cl |in |ascending |Loop |of |Henle
Increase |Na, |K, |Cl |and |Mg |excretion
Increase |urine |output |to |10ml/min
,Can |cause |hypokalemia
Ototoxicity |(deafness |and |balance |problems)
Dehydration |and |electrolyte |imbalance
Block |uric |acid |secretion |-> |Hyperuricemia, |Gout
Reduced |insulin |secretion
Hypocalcemia
Used |in |Edema
Congestive |Heart |Failure
Hypovolemic |based |hypertension
Any |pathological |accumulation |of |non-inflammatory |fluid |(hepatic |cirrhosis)
Ethacrynic |Acid |(Edecrin) |- |CORRECT |ANSWER✔✔-High |Ceiling |Loop |Diuretics
Inhibit |passive |K, |Na |and |Cl |in |ascending |Loop |of |Henle
Increase |Na, |K, |Cl |and |Mg |excretion
Increase |urine |output |to |10ml/min
Can |cause |hypokalemia
Ototoxicity |(deafness |and |balance |problems)
Dehydration |and |electrolyte |imbalance
Block |uric |acid |secretion |-> |Hyperuricemia, |Gout
Reduced |insulin |secretion
Hypocalcemia
Used |in |Edema
,Congestive |Heart |Failure
Hypovolemic |based |hypertension
Any |pathological |accumulation |of |non-inflammatory |fluid |(hepatic |cirrhosis)
Spironolactone |(Aldactone) |- |CORRECT |ANSWER✔✔-Collecting |Duct |Potassium |Sparing |
Diuretics |-
Mineralocorticoid |Receptor |Antagonist |in |Collecting |Duct
Competitive |antagonist |with |aldosterone |in |collecting |duct
Increased |Na+ |and |water |excretion
Decreased |K, |Ca |and |Mg |excretion
Normally |pores |allow |for |Na+ |reabsorption |and |then |subsequent |K+ |excretion
Slow |acting |since |has |to |work |against |existing |aldosterone |pores
Can |cause |hyperkalemia
Treat |primary |aldosteronism |(excessive |aldosterone)
Hypokalemia
Hepatic |Cirrhosis
Congestive |Heart |Failure
Renin |Dependent |Hypertension
Eplerenone |(Inspra) |- |CORRECT |ANSWER✔✔-Collecting |Duct |Potassium |Sparing |Diuretics |-
Mineralocorticoid |Receptor |Antagonist |in |Collecting |Duct
, Competitive |antagonist |with |aldosterone |in |collecting |duct
Increased |Na+ |and |water |excretion
Decreased |K, |Ca |and |Mg |excretion
Normally |pores |allow |for |Na+ |reabsorption |and |then |subsequent |K+ |excretion
Slow |acting |since |has |to |work |against |existing |aldosterone |pores
Can |cause |hyperkalemia
Treat |primary |aldosteronism |(excessive |aldosterone)
Hypokalemia
Hepatic |Cirrhosis
Congestive |Heart |Failure
Renin |Dependent |Hypertension
Triamterene |(Dyrenium) |- |CORRECT |ANSWER✔✔-Potassium |Sparing |Diuretics |- |Collecting |Duct
Na-K |Pore |Blocker
Block |Na |and |K |MR |dependent |pores
Doesn't |depend |on |aldosterone |concentration |since |it |blocks |pore
Rapid |since |no |change |in |protein |production |needed
Increase |Na |excretion
Decreased |K |and |Ca |excretion
Can |get |Hyperkalemia
Correct Answers
Hydrochlorothiazide |- |CORRECT |ANSWER✔✔-K-Wasting |Loop |Diuretics |in |Distal |Tubule
Inhibit |passive |Na |and |Cl |reabsorption |by |symporter |in |distal |tubule
Increase |Na, |K, |Cl |and |Mg |excretion
Decrease |Ca |excretion
Treat |Hypertension
Edema |in |CHF |and |Hepatic |Cirrhosis
Trichlormethiazide |- |CORRECT |ANSWER✔✔-K-Wasting |Loop |Diuretics |in |Distal |Tubule
K-Wasting |Loop |Diuretics |in |Distal |Tubule
Inhibit |passive |Na |and |Cl |reabsorption |by |symporter |in |distal |tubule
Increase |Na, |K, |Cl |and |Mg |excretion
Decrease |Ca |excretion
Treat |Hypertension
Edema |in |CHF |and |Hepatic |Cirrhosis
Furosemide |(LASIX) |- |CORRECT |ANSWER✔✔-High |Ceiling |Loop |Diuretics
Inhibit |passive |K, |Na |and |Cl |in |ascending |Loop |of |Henle
Increase |Na, |K, |Cl |and |Mg |excretion
Increase |urine |output |to |10ml/min
,Can |cause |hypokalemia
Ototoxicity |(deafness |and |balance |problems)
Dehydration |and |electrolyte |imbalance
Block |uric |acid |secretion |-> |Hyperuricemia, |Gout
Reduced |insulin |secretion
Hypocalcemia
Used |in |Edema
Congestive |Heart |Failure
Hypovolemic |based |hypertension
Any |pathological |accumulation |of |non-inflammatory |fluid |(hepatic |cirrhosis)
Ethacrynic |Acid |(Edecrin) |- |CORRECT |ANSWER✔✔-High |Ceiling |Loop |Diuretics
Inhibit |passive |K, |Na |and |Cl |in |ascending |Loop |of |Henle
Increase |Na, |K, |Cl |and |Mg |excretion
Increase |urine |output |to |10ml/min
Can |cause |hypokalemia
Ototoxicity |(deafness |and |balance |problems)
Dehydration |and |electrolyte |imbalance
Block |uric |acid |secretion |-> |Hyperuricemia, |Gout
Reduced |insulin |secretion
Hypocalcemia
Used |in |Edema
,Congestive |Heart |Failure
Hypovolemic |based |hypertension
Any |pathological |accumulation |of |non-inflammatory |fluid |(hepatic |cirrhosis)
Spironolactone |(Aldactone) |- |CORRECT |ANSWER✔✔-Collecting |Duct |Potassium |Sparing |
Diuretics |-
Mineralocorticoid |Receptor |Antagonist |in |Collecting |Duct
Competitive |antagonist |with |aldosterone |in |collecting |duct
Increased |Na+ |and |water |excretion
Decreased |K, |Ca |and |Mg |excretion
Normally |pores |allow |for |Na+ |reabsorption |and |then |subsequent |K+ |excretion
Slow |acting |since |has |to |work |against |existing |aldosterone |pores
Can |cause |hyperkalemia
Treat |primary |aldosteronism |(excessive |aldosterone)
Hypokalemia
Hepatic |Cirrhosis
Congestive |Heart |Failure
Renin |Dependent |Hypertension
Eplerenone |(Inspra) |- |CORRECT |ANSWER✔✔-Collecting |Duct |Potassium |Sparing |Diuretics |-
Mineralocorticoid |Receptor |Antagonist |in |Collecting |Duct
, Competitive |antagonist |with |aldosterone |in |collecting |duct
Increased |Na+ |and |water |excretion
Decreased |K, |Ca |and |Mg |excretion
Normally |pores |allow |for |Na+ |reabsorption |and |then |subsequent |K+ |excretion
Slow |acting |since |has |to |work |against |existing |aldosterone |pores
Can |cause |hyperkalemia
Treat |primary |aldosteronism |(excessive |aldosterone)
Hypokalemia
Hepatic |Cirrhosis
Congestive |Heart |Failure
Renin |Dependent |Hypertension
Triamterene |(Dyrenium) |- |CORRECT |ANSWER✔✔-Potassium |Sparing |Diuretics |- |Collecting |Duct
Na-K |Pore |Blocker
Block |Na |and |K |MR |dependent |pores
Doesn't |depend |on |aldosterone |concentration |since |it |blocks |pore
Rapid |since |no |change |in |protein |production |needed
Increase |Na |excretion
Decreased |K |and |Ca |excretion
Can |get |Hyperkalemia
