CELL SIGNALLING
M. Sudhakara Reddy
Professor
Department of Biotechnology
Thapar Institute of Engineering & Technology
Patiala, Punjab, India
, CELL SIGNALLING- (Brief History)
• In 1970, Martin Rodbell examined effects of glucagon on rat's liver cell membran
receptor
• He revealed about guanosine triphosphate and stimulated G-protein role in ce
metabolism
, AUTOCRINE
cells respond to substances which they themselves release an
thus changes takes place in the cell itself
Example
• Tumour cells
release growth factors for their own survival and proliferation
,
M. Sudhakara Reddy
Professor
Department of Biotechnology
Thapar Institute of Engineering & Technology
Patiala, Punjab, India
, CELL SIGNALLING- (Brief History)
• In 1970, Martin Rodbell examined effects of glucagon on rat's liver cell membran
receptor
• He revealed about guanosine triphosphate and stimulated G-protein role in ce
metabolism
, AUTOCRINE
cells respond to substances which they themselves release an
thus changes takes place in the cell itself
Example
• Tumour cells
release growth factors for their own survival and proliferation
,