FITZGERALD NP CERTIFICATION EXAM SCRIPT
2026 FULL QUESTIONS WITH CORRECT
ANSWERS
◉ a. cephalexin. Answer: in a person with a well-documented hx of
systemic cutaneous reaction without airway impingement following
penicillin use, the use of which of the following cephalosporins is
most likely to result in an allergic response?
a. cephalexin
b. cefprozil
c. ceftriaxone
d. cefpodoxime
◉ b. beta-lactams. Answer: which of the following antimicrobial
classes is associated with the highest rate of allergic reaction?
a. macrolides
b. beta-lactams
c. aminoglycosides
d. sulfonamides
◉ b. refer to allergy and immunology for evaluation. Answer: a 36
y/o man presents for his initial visit to become a pt in a primary care
practice. he is generally in good health with a hx of hyperlipidemia
,and is currently taking an HMG-CoA reductase inhibitor. he reports
that he is allergic to just about every antibiotic, and reports a variety
of reactions including diffuse urticaria, GI upset, and fatigue but
without respiratory involvement. he is unclear as to which
antibiotics have caused these reactions and states that much of what
he knows is from his mother who told me that i always got sicker
instead of better when i took an antibiotic. his last use of an
antimicrobial was more than 10 yrs ago and was without reaction.
he does not recall the name of this med, but remembers that he was
being txed for a sinus infection. the next most appropriate step in his
care is to:
a. advise the pt to obtain a more detailed hx of what antibiotics he
was given during his childhood
b. refer to allergy and immunology for evaluation
c. inform the pt to start an antihistamine whenever he is given an
antibiotic
d. provide a prescription for a systemic corticosteroid to take if he
develops a reaction to his next antimicrobial course
◉ d. fixed drug eruptions. Answer: serious allergic reactions caused
by the use of trimethoprim-sulfamethoxazole include all of the
following EXCEPT:
a. anaphylaxis
b. Stevens-Johnson syndrome
c. toxic epidermal necrolysis
d. fixed drug eruptions
, ◉ c. moxifloxacin. Answer: a 27 y/o woman presents with acute
bacterial rhinosinusitis that has failed to respond to 5 days of txment
with amoxicillin. she reports that she experienced an allergic
reaction to levofloxacin a few yrs ago that caused a rash as well as
swelling of the lips and tongue. in deciding on a new antimicrobial,
you consider avoiding the use of:
a. amoxicillin-clavulanate
b. azithromycin
c. moxifloxacin
d. cefpodoxime
◉ b. if he experiences any allergic reaction, he should stop taking the
antibiotic and contact a healthcare provider immediately. Answer:
you prescribe a regimen of doxycyline to tx an acute exacerbation of
chronic bronchitis for a 56 y/o man. this is his first exposure to this
antimicrobial. you advise that:
a. he should not experience an allergic reaction since he has no
reported penicillin allergy
b. if he experiences any allergic reaction, he should stop taking the
antibiotic and contact a healthcare provider immediately
c. if he experiences an allergic reaction, he should continue taking
the medication until he meets with a healthcare provider to avoid
resistance development
2026 FULL QUESTIONS WITH CORRECT
ANSWERS
◉ a. cephalexin. Answer: in a person with a well-documented hx of
systemic cutaneous reaction without airway impingement following
penicillin use, the use of which of the following cephalosporins is
most likely to result in an allergic response?
a. cephalexin
b. cefprozil
c. ceftriaxone
d. cefpodoxime
◉ b. beta-lactams. Answer: which of the following antimicrobial
classes is associated with the highest rate of allergic reaction?
a. macrolides
b. beta-lactams
c. aminoglycosides
d. sulfonamides
◉ b. refer to allergy and immunology for evaluation. Answer: a 36
y/o man presents for his initial visit to become a pt in a primary care
practice. he is generally in good health with a hx of hyperlipidemia
,and is currently taking an HMG-CoA reductase inhibitor. he reports
that he is allergic to just about every antibiotic, and reports a variety
of reactions including diffuse urticaria, GI upset, and fatigue but
without respiratory involvement. he is unclear as to which
antibiotics have caused these reactions and states that much of what
he knows is from his mother who told me that i always got sicker
instead of better when i took an antibiotic. his last use of an
antimicrobial was more than 10 yrs ago and was without reaction.
he does not recall the name of this med, but remembers that he was
being txed for a sinus infection. the next most appropriate step in his
care is to:
a. advise the pt to obtain a more detailed hx of what antibiotics he
was given during his childhood
b. refer to allergy and immunology for evaluation
c. inform the pt to start an antihistamine whenever he is given an
antibiotic
d. provide a prescription for a systemic corticosteroid to take if he
develops a reaction to his next antimicrobial course
◉ d. fixed drug eruptions. Answer: serious allergic reactions caused
by the use of trimethoprim-sulfamethoxazole include all of the
following EXCEPT:
a. anaphylaxis
b. Stevens-Johnson syndrome
c. toxic epidermal necrolysis
d. fixed drug eruptions
, ◉ c. moxifloxacin. Answer: a 27 y/o woman presents with acute
bacterial rhinosinusitis that has failed to respond to 5 days of txment
with amoxicillin. she reports that she experienced an allergic
reaction to levofloxacin a few yrs ago that caused a rash as well as
swelling of the lips and tongue. in deciding on a new antimicrobial,
you consider avoiding the use of:
a. amoxicillin-clavulanate
b. azithromycin
c. moxifloxacin
d. cefpodoxime
◉ b. if he experiences any allergic reaction, he should stop taking the
antibiotic and contact a healthcare provider immediately. Answer:
you prescribe a regimen of doxycyline to tx an acute exacerbation of
chronic bronchitis for a 56 y/o man. this is his first exposure to this
antimicrobial. you advise that:
a. he should not experience an allergic reaction since he has no
reported penicillin allergy
b. if he experiences any allergic reaction, he should stop taking the
antibiotic and contact a healthcare provider immediately
c. if he experiences an allergic reaction, he should continue taking
the medication until he meets with a healthcare provider to avoid
resistance development
