with Elaborate Answers | Latest
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1. What is the risk of suicide for patients with MDD? - ANSWER About 10 to
15 percent of all depressed patients commit suicide, and about two-thirds
have suicidal ideation.
2. What are the difficulties in recognizing depression in the elderly population?
- ANSWER Elderly people often have various co-morbid medical disorders
that may have similar symptoms to depression.
3. How does the clinician differentiate MDD from Bipolar Disorder? -
ANSWER Episodes of mania-like symptoms, indicating bipolar I disorder
(complete manic and depressive syndromes), bipolar II disorder (recurrent
major depressive episodes with hypomania),
4. What are some psychosocial therapies for the treatment of MDD? -
ANSWER cognitive therapy, interpersonal therapy, and behavior therapy
5. What are the indications for Phototherapy? - ANSWER Seasonal disorders,
sleep disorders.
6. What are the pharmacotherapeutic options in treating MDD? How long
should pharmacotherapy last? How does the clinician select the best
medication for treating MDD? What are the reasons some patients
experience treatment failure? - ANSWER SSRIs, SNRIs, MAOIs,
Tricyclics, atypical antidepressants.
, Should last at least six months, or the duration of the depressed episode.
7. Selection of the initial treatment depends on the chronicity of the condition,
course of illness (a recurrent or chronic course is associated with increased
likelihood of subsequent depressive symptoms without treatment), family
history of illness and treatment response, symptom severity, concurrent
general medical or other psychiatric conditions, prior treatment responses to
other acute phase treatments, potential drug-drug interactions, and patient
preference.
(1) they cannot tolerate the side effects, even in the face of a good clinical
response; (2) an idiosyncratic adverse event may occur; (3) the
clinical response is not adequate; or (4) the wrong diagnosis has been
made.
Review discussion and study guide for Antidepressants: MAOIs, TCAs,
SSRI, SNRIs, Atypical Antipsychotics, Mirtazapine, Buproprion from CMN
548. - ANSWER see text
8. What is SIGECAPS? Why is this mnemonic helpful to the clinician? -
ANSWER Sleep disorder (either increased or decreased sleep)*
Interest deficit (anhedonia)
Guilt (worthlessness,* hopelessness,* regret)
Energy deficit*
Concentration deficit*
Appetite disorder (either decreased or increased)*
Psychomotor retardation or agitation
Suicidality
,9. Patient must have FOUR of these plus depressed mood or anhedonia for at
least two weeks to be diagnosed with MDD.
Review interviewing a patient to assess for mood disorders... - ANSWER see
text
10.What are the diagnostic criteria and clinical features for dysthymia? -
ANSWER This disorder represents a consolidation of DSM-lV-defined
chronic major depressive disorder and dysthymic disorder.
A. Depressed mood for most of the day, for more days than not,
as indicated by either subjective account or observation by
others, for at least 2 years. Note: In children and adolescents,
mood can be irritable and duration must be at least 1 year.
B. Presence, while depressed, of two (or more) of the following:
1. Poor appetite or overeating. 2. Insomnia or hypersomnia. 3.
Low energy or fatigue. 4. Low self-esteem. 5. Poor
concentration or difficulty making decisions. 6. Feelings of
hopelessness.
C. During the 2-year period (1 year for children or adolescents)
of the disturbance, the individual has never been without the
symptoms in Criteria A and B for more than 2 months at a
time.
D. Criteria for a major depressive disorder may be continuously
present for 2 years.
, E. There has never been a manic episode or a hypomanie
episode, and criteria have never been met for cyclothymic
disorder.
F. The disturbance is not better explained by a persistent
schizoaffective disorder, schizophrenia, delusional disorder,
or other specified or unspecified schizophrenia spectrum and
other psychotic disorder.
G. The symptoms are not attributable to the physiological effects
of a substance (e.g., a drug of abuse, a medication) or another
medical condition (e.g. hypothyroidism). H. The symptoms
cause clinically significant distress or impairment in social,
occupational, or other important areas of functioning.
11.What is the epidemiology of dysthymia? - ANSWER Biological:
SLEEP STUDIES: Decreased REM latency and increased REM density are
markers of depression in major depressive disorder that also occur in a
significant proportion of patients with dysthymia.
NEUROENDOCRINE STUDIES: Patients with dysthymia are less likely to have
abnormal results on a DST than are patients with major depressive disorder.
Psychosocial Factors:
Psychodynamic theories about the development of dysthymia posit that the
disorder results from personality and ego development and culminates in difficulty
adapting to adolescence and young adulthood.
What is double depression? - ANSWER An estimated 40 percent of patients with
major depressive disorder also meet the criteria for dysthymia.