TCPS 2: CORE 2022 Questions and Answers
Under which of the following circumstances may a researcher depart from the general principles
of consent (select all that apply)? < ANSWER >When a prospective participant lacks decision-
making capacity.
In medical emergencies
For certain types of public health research.
Which of the following statements is/are true (select all that apply)? < ANSWER >Secondary
use research involves using data that was originally collected for another purpose.
REBs may waive the consent requirement for research involving secondary use of identifiable
information if the researcher satisfies six conditions.
Complete the following sentence in accordance with the guidance in TCPS 2: "Excluding women
from research is ___________." < ANSWER >Ethically unacceptable, unless the exclusion is
related to the nature and scope of the research question.
Which of the following statements reflect TCPS 2 guidance (select all that apply)? < ANSWER
>It is important to communicate research results to participants, in a format suitable to them.
Researchers have a responsibility to disseminate the results of their research, even if those results
do not confirm (or run counter to) their original hypothesis.
Under TCPS 2, can individuals who are in vulnerable circumstances participate in research? <
ANSWER >Yes, so long as their participation is necessary to the research and additional
protective measures are in place.
The principle of Justice requires an equitable distribution of the benefits and burdens of research
because (select all that apply): < ANSWER >This helps to maintain public trust in research.
This contributes to the legitimacy of research results by ensuring that research findings are drawn
from the full range of those to whom the research applies.
This avoids disadvantaged or marginalized groups from bearing a disproportionate share of
research risks.
Which of the following statements is correct (select all that apply)? < ANSWER >Researchers
have an ethical duty to maintain the confidentiality of information they collect during the course
of research.
A researcher's duty of confidentiality extends to human biological materials collected during the
course of research.
Researchers may have legal obligations to maintain the privacy of research participants.
Secondary use research is: < ANSWER >Research that relies on information originally collected
for a purpose other than the current research purpose.
Who has responsibility for safeguarding the privacy of research participants (select the most
appropriate answer): < ANSWER >Researchers, REBs, and institutions.
, The level of privacy protection required is based on the identifiability of the information. Which
of the following is not a category of identifiability set out in the TCPS 2? < ANSWER >Secret
information.
In research, conflict of interest is an issue that can affect (select the most appropriate answer): <
ANSWER >Researchers, REB members, and institutions.
Which of the following statements is/are true (select all that apply)? < ANSWER >Conflicts of
interest may be real, potential, or perceived.
A conflict of interest in research is an incompatibility between all of one's duties,
responsibilities, or interests, as they relate to the ethical conduct of research.
Which of the following would be a conflict of interest for REB members (select all that apply)?
< ANSWER >REB members supervise the researcher submitting the protocol for REB review.
REB members sit on the board of the company that is sponsoring the research.
REB members are collaborating with the research applicant on another research project.
The research applicant is their sister-in-law.
The research applicant is their supervisor.
REB members own shares in the company that is sponsoring the research.
Which of the following is/are an acceptable way for a researcher to manage a conflict of interest
(select all that apply)? < ANSWER >Develop a plan to minimize the effect of the conflict.
Disclose to the REB and to participants.
Addressing conflicts of interest in research involving humans is important because (select all that
apply): < ANSWER >It helps to protect the integrity of research.
It is part of the process of ensuring that prospective research participants make informed
decisions regarding their consent to participate.
Which of the following activities is not a primary responsibility of an REB?
To review the ethical acceptability of the methods of a research proposal.
To review the ethical acceptability of the design of a research proposal.
To review substantive changes made to the research during the course of a study.
To provide advice about alternative methods to answer the research question.
To communicate their decisions in a timely and efficient manner. < ANSWER >To provide
advice about alternative methods to answer the research question.
Which one of the following statements best describes the status of an REB?
A committee accountable in all respects to the institution that created it.
A committee accountable to the institution that created it with respect to its operations, but
independent with respect to its decisions on research proposals.
A committee independent in all respects from the institution that created it. < ANSWER >A
committee accountable to the institution that created it with respect to its operations, but
independent with respect to its decisions on research proposals.
Under which of the following circumstances may a researcher depart from the general principles
of consent (select all that apply)? < ANSWER >When a prospective participant lacks decision-
making capacity.
In medical emergencies
For certain types of public health research.
Which of the following statements is/are true (select all that apply)? < ANSWER >Secondary
use research involves using data that was originally collected for another purpose.
REBs may waive the consent requirement for research involving secondary use of identifiable
information if the researcher satisfies six conditions.
Complete the following sentence in accordance with the guidance in TCPS 2: "Excluding women
from research is ___________." < ANSWER >Ethically unacceptable, unless the exclusion is
related to the nature and scope of the research question.
Which of the following statements reflect TCPS 2 guidance (select all that apply)? < ANSWER
>It is important to communicate research results to participants, in a format suitable to them.
Researchers have a responsibility to disseminate the results of their research, even if those results
do not confirm (or run counter to) their original hypothesis.
Under TCPS 2, can individuals who are in vulnerable circumstances participate in research? <
ANSWER >Yes, so long as their participation is necessary to the research and additional
protective measures are in place.
The principle of Justice requires an equitable distribution of the benefits and burdens of research
because (select all that apply): < ANSWER >This helps to maintain public trust in research.
This contributes to the legitimacy of research results by ensuring that research findings are drawn
from the full range of those to whom the research applies.
This avoids disadvantaged or marginalized groups from bearing a disproportionate share of
research risks.
Which of the following statements is correct (select all that apply)? < ANSWER >Researchers
have an ethical duty to maintain the confidentiality of information they collect during the course
of research.
A researcher's duty of confidentiality extends to human biological materials collected during the
course of research.
Researchers may have legal obligations to maintain the privacy of research participants.
Secondary use research is: < ANSWER >Research that relies on information originally collected
for a purpose other than the current research purpose.
Who has responsibility for safeguarding the privacy of research participants (select the most
appropriate answer): < ANSWER >Researchers, REBs, and institutions.
, The level of privacy protection required is based on the identifiability of the information. Which
of the following is not a category of identifiability set out in the TCPS 2? < ANSWER >Secret
information.
In research, conflict of interest is an issue that can affect (select the most appropriate answer): <
ANSWER >Researchers, REB members, and institutions.
Which of the following statements is/are true (select all that apply)? < ANSWER >Conflicts of
interest may be real, potential, or perceived.
A conflict of interest in research is an incompatibility between all of one's duties,
responsibilities, or interests, as they relate to the ethical conduct of research.
Which of the following would be a conflict of interest for REB members (select all that apply)?
< ANSWER >REB members supervise the researcher submitting the protocol for REB review.
REB members sit on the board of the company that is sponsoring the research.
REB members are collaborating with the research applicant on another research project.
The research applicant is their sister-in-law.
The research applicant is their supervisor.
REB members own shares in the company that is sponsoring the research.
Which of the following is/are an acceptable way for a researcher to manage a conflict of interest
(select all that apply)? < ANSWER >Develop a plan to minimize the effect of the conflict.
Disclose to the REB and to participants.
Addressing conflicts of interest in research involving humans is important because (select all that
apply): < ANSWER >It helps to protect the integrity of research.
It is part of the process of ensuring that prospective research participants make informed
decisions regarding their consent to participate.
Which of the following activities is not a primary responsibility of an REB?
To review the ethical acceptability of the methods of a research proposal.
To review the ethical acceptability of the design of a research proposal.
To review substantive changes made to the research during the course of a study.
To provide advice about alternative methods to answer the research question.
To communicate their decisions in a timely and efficient manner. < ANSWER >To provide
advice about alternative methods to answer the research question.
Which one of the following statements best describes the status of an REB?
A committee accountable in all respects to the institution that created it.
A committee accountable to the institution that created it with respect to its operations, but
independent with respect to its decisions on research proposals.
A committee independent in all respects from the institution that created it. < ANSWER >A
committee accountable to the institution that created it with respect to its operations, but
independent with respect to its decisions on research proposals.
